Page last updated: 2024-10-22

amitriptyline and Dementia, Vascular

amitriptyline has been researched along with Dementia, Vascular in 2 studies

Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.

Dementia, Vascular: An imprecise term referring to dementia associated with CEREBROVASCULAR DISORDERS, including CEREBRAL INFARCTION (single or multiple), and conditions associated with chronic BRAIN ISCHEMIA. Diffuse, cortical, and subcortical subtypes have been described. (From Gerontol Geriatr 1998 Feb;31(1):36-44)

Research Excerpts

ExcerptRelevanceReference
"Binswanger's disease is a cerebrovascular disorder affecting deep white matter and is associated with dementia and affective disturbance."1.28Treatment of mood disorder associated with Binswanger's disease. ( Joyce, EM; Levy, R, 1989)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
González Moneo, MJ1
Garrido Barral, A1
Joyce, EM1
Levy, R1

Reviews

1 review available for amitriptyline and Dementia, Vascular

ArticleYear
[Latest therapies for treating dementia].
    Atencion primaria, 2002, May-15, Volume: 29, Issue:8

    Topics: Adult; Aged; Alzheimer Disease; Amitriptyline; Antidepressive Agents, Second-Generation; Antidepress

2002

Other Studies

1 other study available for amitriptyline and Dementia, Vascular

ArticleYear
Treatment of mood disorder associated with Binswanger's disease.
    The British journal of psychiatry : the journal of mental science, 1989, Volume: 154

    Topics: Aged; Amitriptyline; Dementia, Vascular; Humans; Lithium; Male; Mood Disorders

1989