amitriptyline has been researched along with Delayed Effects, Prenatal Exposure in 6 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The study determined whether oral administration of amitriptyline for 6 weeks from before puberty to prenatally stressed (PS) male and female rats could prevent hyperanxiety in adulthood." | 7.72 | Gender difference in the prevention of hyperanxiety in adult prenatally stressed rats by chronic treatment with amitriptyline. ( Poltyrev, T; Weinstock, M, 2004) |
| "The study determined whether oral administration of amitriptyline for 6 weeks from before puberty to prenatally stressed (PS) male and female rats could prevent hyperanxiety in adulthood." | 3.72 | Gender difference in the prevention of hyperanxiety in adult prenatally stressed rats by chronic treatment with amitriptyline. ( Poltyrev, T; Weinstock, M, 2004) |
| " To determine the long term effects of cocaine on a developing fetus, gravid rats were dosed SC throughout pregnancy with either saline, amfonelic acid (AFA, 1." | 1.28 | Effects of prenatal exposure to cocaine or related drugs on rat developmental and neurological indices. ( Henderson, MG; McMillen, BA, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (66.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abdul Aziz, NH | 1 |
| Kendall, DA | 1 |
| Pardon, MC | 1 |
| Poltyrev, T | 1 |
| Weinstock, M | 1 |
| Henderson, MG | 3 |
| McMillen, BA | 3 |
| Alonso, SJ | 1 |
| Castellano, MA | 1 |
| Quintero, M | 1 |
| Navarro, E | 1 |
| McConnaughey, MM | 1 |
6 other studies available for amitriptyline and Delayed Effects, Prenatal Exposure
| Article | Year |
|---|---|
Prenatal exposure to chronic mild stress increases corticosterone levels in the amniotic fluid and induces cognitive deficits in female offspring, improved by treatment with the antidepressant drug amitriptyline.
Topics: Amitriptyline; Amniotic Fluid; Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Fem | 2012 |
Gender difference in the prevention of hyperanxiety in adult prenatally stressed rats by chronic treatment with amitriptyline.
Topics: Amitriptyline; Animals; Anxiety; Female; Locomotion; Male; Pregnancy; Prenatal Exposure Delayed Effe | 2004 |
Changes in dopamine, serotonin and their metabolites in discrete brain areas of rat offspring after in utero exposure to cocaine or related drugs.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Amitriptyline; Amygdala; Analysis of Variance; Animals; Brain | 1993 |
Action of antidepressant drugs on maternal stress-induced hypoactivity in female rats.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Dose-Response Relationsh | 1999 |
Long-term consequences of prenatal exposure to cocaine or related drugs: effects on rat brain monoaminergic receptors.
Topics: Aging; Amitriptyline; Animals; Brain; Cerebral Cortex; Cocaine; Corpus Striatum; Female; Male; Nalid | 1991 |
Effects of prenatal exposure to cocaine or related drugs on rat developmental and neurological indices.
Topics: Amitriptyline; Animals; Cocaine; Female; Hyperkinesis; Male; Nervous System; Pregnancy; Prenatal Exp | 1990 |