amitriptyline has been researched along with Degenerative Diseases, Central Nervous System in 2 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kwon, Y | 1 |
| Bang, Y | 1 |
| Moon, SH | 1 |
| Kim, A | 1 |
| Choi, HJ | 1 |
| Paumier, KL | 1 |
| Sortwell, CE | 1 |
| Madhavan, L | 1 |
| Terpstra, B | 1 |
| Celano, SL | 1 |
| Green, JJ | 1 |
| Imus, NM | 1 |
| Marckini, N | 1 |
| Daley, B | 1 |
| Steece-Collier, K | 1 |
| Collier, TJ | 1 |
2 other studies available for amitriptyline and Degenerative Diseases, Central Nervous System
| Article | Year |
|---|---|
Amitriptyline interferes with autophagy-mediated clearance of protein aggregates via inhibiting autophagosome maturation in neuronal cells.
Topics: Amitriptyline; Animals; Autophagosomes; Autophagy; Depressive Disorder, Major; Lysosomes; Neurodegen | 2020 |
Chronic amitriptyline treatment attenuates nigrostriatal degeneration and significantly alters trophic support in a rat model of parkinsonism.
Topics: Adrenergic Agents; Amitriptyline; Analgesics, Non-Narcotic; Animals; Brain-Derived Neurotrophic Fact | 2015 |