amitriptyline has been researched along with Cystitis in 6 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Cystitis: Inflammation of the URINARY BLADDER, either from bacterial or non-bacterial causes. Cystitis is usually associated with painful urination (dysuria), increased frequency, urgency, and suprapubic pain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Limited data and an accumulated body of anecdotal experience with the tricyclic class of antidepressants suggest that this group of drugs (especially amitriptyline) may be an effective treatment modality in nonulcerative interstitial cystitis." | 8.79 | Amitriptyline in the treatment of interstitial cystitis. ( Hanno, PM, 1994) |
| "To evaluate the safety and efficacy of amitriptyline hydrochloride in the treatment of severe recurrent idiopathic cystitis (IC) in cats." | 7.70 | Amitriptyline treatment for severe recurrent idiopathic cystitis in cats. ( Buffington, CA; Chew, DJ; DiBartola, SP; Kendall, MS; Woodworth, BE, 1998) |
| "A total of 25 patients with interstitial cystitis who had failed standard therapy with hydrodistension of the bladder during anesthesia and intravesical dimethyl sulfoxide instillation underwent treatment with the tricyclic antidepressant amitriptyline." | 7.67 | Use of amitriptyline in the treatment of interstitial cystitis. ( Buehler, J; Hanno, PM; Wein, AJ, 1989) |
| "To evaluate the safety and efficacy of amitriptyline hydrochloride in the treatment of severe recurrent idiopathic cystitis (IC) in cats." | 3.70 | Amitriptyline treatment for severe recurrent idiopathic cystitis in cats. ( Buffington, CA; Chew, DJ; DiBartola, SP; Kendall, MS; Woodworth, BE, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dogishi, K | 1 |
| Kodera, M | 1 |
| Oyama, S | 1 |
| Shirakawa, H | 1 |
| Nakagawa, T | 1 |
| Kaneko, S | 1 |
| Hanno, PM | 4 |
| Chew, DJ | 1 |
| Buffington, CA | 1 |
| Kendall, MS | 1 |
| DiBartola, SP | 1 |
| Woodworth, BE | 1 |
| Wein, AJ | 3 |
| Buehler, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Trial of Bladder Instillations Versus Onabotulinumtoxin A for Treatment of Interstitial Cystitis/Bladder Pain Syndrome[NCT04401176] | Phase 2 | 58 participants (Actual) | Interventional | 2020-09-15 | Completed | ||
| Intravesical Botulinum Toxin A Injection in Treatment of Interstitial Cystitis Refractory to Conventional Treatment - A Prospective, Multicenter, Randomized, Double-blind, Placebo-controlled Clinical Trial[NCT01969773] | Phase 2 | 60 participants (Actual) | Interventional | 2012-12-31 | Completed | ||
| Low Energy Shock Wave for the Treatment of Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) - a Randomized, Double-blind, Placebo-controlled, Prospective Study[NCT03619486] | 49 participants (Actual) | Interventional | 2018-07-04 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for amitriptyline and Cystitis
| Article | Year |
|---|---|
Amitriptyline in the treatment of interstitial cystitis.
Topics: Amitriptyline; Animals; Clinical Trials as Topic; Cystitis; Humans | 1994 |
Medical treatment of interstitial cystitis (other than Rimso-50/Elmiron).
Topics: Administration, Intravesical; Administration, Oral; Amitriptyline; Azathioprine; Benzenesulfonates; | 1987 |
4 other studies available for amitriptyline and Cystitis
| Article | Year |
|---|---|
Long-lasting pain-related behaviors in mouse chronic cystitis model induced by a single intravesical injection of hydrogen peroxide.
Topics: Administration, Intravesical; Amitriptyline; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; | 2015 |
Amitriptyline treatment for severe recurrent idiopathic cystitis in cats.
Topics: Adrenergic Uptake Inhibitors; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Cat Diseases | 1998 |
Conservative therapy of interstitial cystitis.
Topics: Adult; Amitriptyline; Cystitis; Dilatation; Dimethyl Sulfoxide; Female; Humans; Male; Middle Aged; P | 1991 |
Use of amitriptyline in the treatment of interstitial cystitis.
Topics: Adult; Aged; Aged, 80 and over; Amitriptyline; Analgesics; Cystitis; Female; Humans; Middle Aged; Ti | 1989 |
Use of amitriptyline in the treatment of interstitial cystitis.
Topics: Adult; Aged; Aged, 80 and over; Amitriptyline; Analgesics; Cystitis; Female; Humans; Middle Aged; Ti | 1989 |
Use of amitriptyline in the treatment of interstitial cystitis.
Topics: Adult; Aged; Aged, 80 and over; Amitriptyline; Analgesics; Cystitis; Female; Humans; Middle Aged; Ti | 1989 |
Use of amitriptyline in the treatment of interstitial cystitis.
Topics: Adult; Aged; Aged, 80 and over; Amitriptyline; Analgesics; Cystitis; Female; Humans; Middle Aged; Ti | 1989 |