amitriptyline has been researched along with Craniocerebral Trauma in 6 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Craniocerebral Trauma: Traumatic injuries involving the cranium and intracranial structures (i.e., BRAIN; CRANIAL NERVES; MENINGES; and other structures). Injuries may be classified by whether or not the skull is penetrated (i.e., penetrating vs. nonpenetrating) or whether there is an associated hemorrhage.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Amitriptyline was the most useful drug in that it provided pain relief in musculoskeletal, vascular, and some neuropathic pain conditions." | 3.69 | Diagnosis and treatment of persistent pain after trauma to the head and neck. ( Benoliel, R; Eliav, E; Elishoov, H; Sharav, Y, 1994) |
| "The response to prophylactic anti-migraine medication (propranolol or amitriptyline used alone or in combination) was gratifying, with 21 of 30 adequately treated patients (70%) reporting dramatic reduction in the frequency and severity of their headaches." | 1.28 | Post-traumatic migraine: chronic migraine precipitated by minor head or neck trauma. ( Goldberg, J; Stern, BJ; Weiss, HD, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kemp, S | 1 |
| Biswas, R | 1 |
| Neumann, V | 1 |
| Coughlan, A | 1 |
| Tyler, GS | 1 |
| McNeely, HE | 1 |
| Dick, ML | 1 |
| Benoliel, R | 1 |
| Eliav, E | 1 |
| Elishoov, H | 1 |
| Sharav, Y | 1 |
| Bauherz, G | 1 |
| Weiss, HD | 1 |
| Stern, BJ | 1 |
| Goldberg, J | 1 |
| Saran, AS | 1 |
1 review available for amitriptyline and Craniocerebral Trauma
| Article | Year |
|---|---|
[Chronic headaches].
Topics: Amitriptyline; Analgesics; Antidepressive Agents, Tricyclic; Chronic Disease; Craniocerebral Trauma; | 2000 |
1 trial available for amitriptyline and Craniocerebral Trauma
| Article | Year |
|---|---|
The value of melatonin for sleep disorders occurring post-head injury: a pilot RCT.
Topics: Adolescent; Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Antioxidants; Cognition; Cranioc | 2004 |
4 other studies available for amitriptyline and Craniocerebral Trauma
| Article | Year |
|---|---|
Treatment of post-traumatic headache with amitriptyline.
Topics: Adult; Amitriptyline; Craniocerebral Trauma; Headache; Humans; Middle Aged | 1980 |
Diagnosis and treatment of persistent pain after trauma to the head and neck.
Topics: Adult; Amitriptyline; Carbamazepine; Chronic Disease; Craniocerebral Trauma; Facial Pain; Female; He | 1994 |
Post-traumatic migraine: chronic migraine precipitated by minor head or neck trauma.
Topics: Adolescent; Adult; Amitriptyline; Chronic Disease; Craniocerebral Trauma; Female; Humans; Male; Midd | 1991 |
Depression after minor closed head injury: role of dexamethasone suppression test and antidepressants.
Topics: Adult; Amitriptyline; Craniocerebral Trauma; Depressive Disorder; Dexamethasone; Female; Humans; Hyd | 1985 |