amitriptyline has been researched along with Cough in 10 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Cough: A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The objective of this prospective, randomized, controlled study (N = 28) was to evaluate the effectiveness of amitriptyline versus cough suppressants in the treatment of chronic cough resulting from postviral vagal neuropathy." | 9.12 | Effectiveness of amitriptyline versus cough suppressants in the treatment of chronic cough resulting from postviral vagal neuropathy. ( Brickman, TM; Haben, M; Jeyakumar, A, 2006) |
| "To evaluate short- and long-term treatment outcomes of amitriptyline for idiopathic cough." | 7.83 | Long-term follow-up of amitriptyline treatment for idiopathic cough. ( Cohen, SM; Ryan, MA, 2016) |
| "The objective of this prospective, randomized, controlled study (N = 28) was to evaluate the effectiveness of amitriptyline versus cough suppressants in the treatment of chronic cough resulting from postviral vagal neuropathy." | 5.12 | Effectiveness of amitriptyline versus cough suppressants in the treatment of chronic cough resulting from postviral vagal neuropathy. ( Brickman, TM; Haben, M; Jeyakumar, A, 2006) |
| "The goal of this systematic review was to examine the evidence for the use of the neuromodulating agents, amitriptyline, gabapentin, pregabalin, and baclofen, in the management of chronic, idiopathic cough patients." | 4.89 | Use of specific neuromodulators in the treatment of chronic, idiopathic cough: a systematic review. ( Cohen, SM; Misono, S, 2013) |
| "Objective To evaluate the short- and long-term effects of tricyclic antidepressants (TCAs) and gabapentin in the treatment of unexplained chronic cough (UCC)." | 3.88 | Short- and Long-term Effects of Neuromodulators for Unexplained Chronic Cough. ( Adessa, M; Benninger, MS; Bowen, AJ; Bryson, PC; Contrera, K; Kaltenbach, J; Milstein, CF; Nowacki, AS; Taliercio, R; Trask, D, 2018) |
| "To describe our experience with chronic sensory neuropathic cough and its response to amitriptyline in a first group of patients." | 3.73 | Sensory neuropathic cough: a common and treatable cause of chronic cough. ( Bastian, RW; Delsupehe, KG; Vaidya, AM, 2006) |
| "Unexplained cough is a diagnosis of exclusion that should not be made until a thorough validated diagnostic evaluation is performed, specific and appropriate validated treatments have been tried and failed, and uncommon causes have been ruled out." | 1.36 | Unexplained cough in the adult. ( Irwin, RS, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 7 (70.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Guilleminault, L | 1 |
| Demoulin-Alexikova, S | 1 |
| de Gabory, L | 1 |
| Bruley des Varannes, S | 1 |
| Brouquières, D | 1 |
| Balaguer, M | 1 |
| Chapron, A | 1 |
| Grassin Delyle, S | 1 |
| Poussel, M | 1 |
| Guibert, N | 1 |
| Reychler, G | 1 |
| Trzepizur, W | 1 |
| Woisard, V | 1 |
| Crestani, S | 1 |
| Bowen, AJ | 1 |
| Nowacki, AS | 1 |
| Contrera, K | 1 |
| Trask, D | 1 |
| Kaltenbach, J | 1 |
| Milstein, CF | 1 |
| Adessa, M | 1 |
| Benninger, MS | 1 |
| Taliercio, R | 1 |
| Bryson, PC | 1 |
| Ryan, MA | 1 |
| Cohen, SM | 3 |
| Giliberto, JP | 1 |
| Misono, S | 2 |
| Greene, SM | 1 |
| Simpson, CB | 1 |
| Irwin, RS | 1 |
| Norris, BK | 1 |
| Schweinfurth, JM | 1 |
| Bastian, RW | 1 |
| Vaidya, AM | 1 |
| Delsupehe, KG | 1 |
| Jeyakumar, A | 1 |
| Brickman, TM | 1 |
| Haben, M | 1 |
3 reviews available for amitriptyline and Cough
| Article | Year |
|---|---|
Are neuromodulating medications effective for the treatment of chronic neurogenic cough?
Topics: Amines; Amitriptyline; Chronic Disease; Cough; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminob | 2017 |
Evidence for sensory neuropathy and pharmacologic management.
Topics: Adrenergic Uptake Inhibitors; Amines; Amitriptyline; Anticonvulsants; Chronic Disease; Cough; Cycloh | 2010 |
Use of specific neuromodulators in the treatment of chronic, idiopathic cough: a systematic review.
Topics: Amines; Amitriptyline; Baclofen; Chronic Disease; Cough; Cyclohexanecarboxylic Acids; Gabapentin; ga | 2013 |
1 trial available for amitriptyline and Cough
| Article | Year |
|---|---|
Effectiveness of amitriptyline versus cough suppressants in the treatment of chronic cough resulting from postviral vagal neuropathy.
Topics: Amitriptyline; Antitussive Agents; Chronic Disease; Codeine; Cough; Drug Combinations; Expectorants; | 2006 |
6 other studies available for amitriptyline and Cough
| Article | Year |
|---|---|
[Guidelines for the management of chronic cough in adults].
Topics: Adult; Amitriptyline; Chronic Disease; Cough; Gabapentin; Humans; Quality of Life | 2023 |
Short- and Long-term Effects of Neuromodulators for Unexplained Chronic Cough.
Topics: Adult; Aged; Amitriptyline; Chronic Disease; Cohort Studies; Cough; Dose-Response Relationship, Drug | 2018 |
Long-term follow-up of amitriptyline treatment for idiopathic cough.
Topics: Adult; Aged; Aged, 80 and over; Amitriptyline; Analgesics, Non-Narcotic; Cough; Female; Follow-Up St | 2016 |
Unexplained cough in the adult.
Topics: Adrenergic Uptake Inhibitors; Adult; Amitriptyline; Analgesics, Opioid; Angiotensin-Converting Enzym | 2010 |
Management of recurrent laryngeal sensory neuropathic symptoms.
Topics: Adrenergic Uptake Inhibitors; Aged; Amines; Amitriptyline; Cough; Cranial Nerve Diseases; Cyclohexan | 2010 |
Sensory neuropathic cough: a common and treatable cause of chronic cough.
Topics: Adrenergic Uptake Inhibitors; Adult; Aged; Amitriptyline; Bronchial Provocation Tests; Bronchoscopy; | 2006 |