amitriptyline has been researched along with Costen's Syndrome in 6 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Depression was assessed by the Beck Depression Inventory (BDI) short form." | 6.69 | Amitriptyline treatment of chronic pain in patients with temporomandibular disorders. ( Curtis, D; Levine, J; McCall, WD; Plesh, O, 2000) |
| "Amitriptyline was the most useful drug in that it provided pain relief in musculoskeletal, vascular, and some neuropathic pain conditions." | 3.69 | Diagnosis and treatment of persistent pain after trauma to the head and neck. ( Benoliel, R; Eliav, E; Elishoov, H; Sharav, Y, 1994) |
| "Depression was assessed by the Beck Depression Inventory (BDI) short form." | 2.69 | Amitriptyline treatment of chronic pain in patients with temporomandibular disorders. ( Curtis, D; Levine, J; McCall, WD; Plesh, O, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alencar, FG | 1 |
| Viana, PG | 1 |
| Zamperini, C | 1 |
| Becker, A | 1 |
| Haviv, Y | 1 |
| Rettman, A | 1 |
| Aframian, D | 1 |
| Sharav, Y | 2 |
| Benoliel, R | 2 |
| Eliav, E | 1 |
| Elishoov, H | 1 |
| Plesh, O | 1 |
| Curtis, D | 1 |
| Levine, J | 1 |
| McCall, WD | 1 |
| Herman, CR | 1 |
| Schiffman, EL | 1 |
| Look, JO | 1 |
| Rindal, DB | 1 |
| Moore, DS | 1 |
| Nally, FF | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Side Effects of Two Different Mandibular Advancement Devices (MAD) in the Treatment of Snoring and Obstructive Sleep Apnea Syndrome (OSAS)[NCT04050514] | 65 participants (Actual) | Interventional | 2019-12-01 | Completed | |||
| Prospective, Cross Over Gabapentin vs Amitriptyline Study on Patients Suffering From Masticatory Muscle Pain[NCT02339662] | Phase 4 | 50 participants (Anticipated) | Interventional | 2015-02-28 | Recruiting | ||
| Preliminary Findings of the Efficacy of Botulinum Toxin in Temporomandibular Disorders: A Randomized Clinical Trial[NCT05651256] | Phase 2/Phase 3 | 20 participants (Actual) | Interventional | 2021-03-01 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 trials available for amitriptyline and Costen's Syndrome
| Article | Year |
|---|---|
Patient education and self-care for the management of jaw pain upon awakening: a randomized controlled clinical trial comparing the effectiveness of adding pharmacologic treatment with cyclobenzaprine or tizanidine.
Topics: Adolescent; Adult; Aged; Amitriptyline; Analgesics, Non-Narcotic; Clonidine; Double-Blind Method; Fa | 2014 |
Myofascial pain: an open study on the pharmacotherapeutic response to stepped treatment with tricyclic antidepressants and gabapentin.
Topics: Adult; Age Factors; Amines; Amitriptyline; Antidepressive Agents, Tricyclic; Comorbidity; Cyclohexan | 2015 |
Amitriptyline treatment of chronic pain in patients with temporomandibular disorders.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Chronic Disease; Depression; Facial Pain; Fe | 2000 |
The effectiveness of adding pharmacologic treatment with clonazepam or cyclobenzaprine to patient education and self-care for the treatment of jaw pain upon awakening: a randomized clinical trial.
Topics: Adult; Amitriptyline; Clonazepam; Female; GABA Modulators; Health Education, Dental; Humans; Male; M | 2002 |
2 other studies available for amitriptyline and Costen's Syndrome
| Article | Year |
|---|---|
Diagnosis and treatment of persistent pain after trauma to the head and neck.
Topics: Adult; Amitriptyline; Carbamazepine; Chronic Disease; Craniocerebral Trauma; Facial Pain; Female; He | 1994 |
Atypical facial pain: an analysis of 100 patients with discussion.
Topics: Adult; Age Factors; Amitriptyline; Anxiety Disorders; Chlordiazepoxide; Depression; Diagnosis, Diffe | 1975 |