Page last updated: 2024-10-22

amitriptyline and Coronary Disease

amitriptyline has been researched along with Coronary Disease in 6 studies

Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.

Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.

Research Excerpts

ExcerptRelevanceReference
" We studied lipoprotein composition, insulin sensitivity (quantitative insulin sensitivity check index), and saliva cortisol in 78 depressed patients before and after 35 days of amitriptyline or paroxetin treatment."3.72Lipid metabolism and insulin resistance in depressed patients: significance of weight, hypercortisolism, and antidepressant treatment. ( Deuschle, M; Gilles, M; Henn, FA; Heuser, I; Kopf, D; Lederbogen, F; Lehnert, H; Luley, CW; Ritter, S; Weber-Hamann, B; Westphal, S, 2004)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19905 (83.33)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
BATTERMAN, RC1
KAUFMAN, JE1
MOURATOFF, GJ1
Kopf, D1
Westphal, S1
Luley, CW1
Ritter, S1
Gilles, M1
Weber-Hamann, B1
Lederbogen, F1
Lehnert, H1
Henn, FA1
Heuser, I1
Deuschle, M1
Zaĭtsev, VP2
Kol'tsova, TI2
Kilpatrick, R1
Smith, AJ1
Kelly, RE1

Reviews

1 review available for amitriptyline and Coronary Disease

ArticleYear
Advances in medicine.
    The Practitioner, 1971, Volume: 207, Issue:240

    Topics: Amitriptyline; Cholera; Coronary Disease; Crohn Disease; Diabetes Mellitus; Diet Therapy; Diverticul

1971

Trials

1 trial available for amitriptyline and Coronary Disease

ArticleYear
[Comparative effectiveness of tricyclic antidepressants in the treatment of psychic changes in ischemic heart disease].
    Terapevticheskii arkhiv, 1980, Volume: 52, Issue:5

    Topics: Adult; Affective Symptoms; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Clinical Trials as

1980

Other Studies

4 other studies available for amitriptyline and Coronary Disease

ArticleYear
CLINICAL USE OF AMITRIPTYLINE FOR THE TREATMENT OF PSYCHONEUROTIC REACTIVE ANXIETY AND DEPRESSION.
    Current therapeutic research, clinical and experimental, 1964, Volume: 6

    Topics: Amitriptyline; Anxiety; Arthritis, Rheumatoid; Asthma; Coronary Disease; Depression; Diabetes Mellit

1964
Lipid metabolism and insulin resistance in depressed patients: significance of weight, hypercortisolism, and antidepressant treatment.
    Journal of clinical psychopharmacology, 2004, Volume: 24, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Amitriptyline; Analysis of Variance; Antidepressive Agents; Blood Gl

2004
[Comparative effectiveness of various tricyclic antidepressive agents in ischemic heart disease].
    Klinicheskaia meditsina, 1977, Volume: 55, Issue:9

    Topics: Adult; Affective Symptoms; Aged; Amitriptyline; Coronary Disease; Drug Evaluation; Humans; Male; Mid

1977
Methysergide and coronary thrombosis.
    The Practitioner, 1965, Volume: 195, Issue:168

    Topics: Amitriptyline; Coronary Disease; Headache; Humans; Male; Methysergide; Middle Aged; Vascular Headach

1965