amitriptyline has been researched along with Congenital Myotonic Dystrophy in 1 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this study was to quantify the degree of muscle weakness and myotonia in 12 patients with myotonic dystrophy (MD), and to quantitatively determine the effects of a four- to six-month therapeutic trial of amitriptyline." | 7.68 | Myotonic dystrophy: quantification of muscle weakness and myotonia and the effect of amitriptyline and exercise. ( Miller, RG; Milner-Brown, HS, 1990) |
| "The purpose of this study was to quantify the degree of muscle weakness and myotonia in 12 patients with myotonic dystrophy (MD), and to quantitatively determine the effects of a four- to six-month therapeutic trial of amitriptyline." | 3.68 | Myotonic dystrophy: quantification of muscle weakness and myotonia and the effect of amitriptyline and exercise. ( Miller, RG; Milner-Brown, HS, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Milner-Brown, HS | 1 |
| Miller, RG | 1 |
1 other study available for amitriptyline and Congenital Myotonic Dystrophy
| Article | Year |
|---|---|
Myotonic dystrophy: quantification of muscle weakness and myotonia and the effect of amitriptyline and exercise.
Topics: Action Potentials; Adult; Amitriptyline; Arrhythmias, Cardiac; Exercise Therapy; Female; Humans; Mal | 1990 |