amitriptyline has been researched along with Colitis in 3 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Both had received a commonly used psychotropic drug in large dosage before the acute episode." | 1.27 | Ischaemic colitis associated with psychotropic drugs. ( Gollock, JM; Thomson, JP, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Dejban, P | 1 |
| Sahraei, M | 1 |
| Chamanara, M | 1 |
| Dehpour, A | 1 |
| Rashidian, A | 1 |
| Meiners, J | 1 |
| Palmieri, V | 1 |
| Klopfleisch, R | 1 |
| Ebel, JF | 1 |
| Japtok, L | 1 |
| Schumacher, F | 1 |
| Yusuf, AM | 1 |
| Becker, KA | 1 |
| Zöller, J | 1 |
| Hose, M | 1 |
| Kleuser, B | 1 |
| Hermann, DM | 1 |
| Kolesnick, RN | 1 |
| Buer, J | 1 |
| Hansen, W | 1 |
| Westendorf, AM | 1 |
| Gollock, JM | 1 |
| Thomson, JP | 1 |
3 other studies available for amitriptyline and Colitis
| Article | Year |
|---|---|
Anti-inflammatory effect of amitriptyline in a rat model of acetic acid-induced colitis: the involvement of the TLR4/NF-kB signaling pathway.
Topics: Acetic Acid; Administration, Oral; Amitriptyline; Animals; Anti-Inflammatory Agents; Colitis; Diseas | 2021 |
Intestinal Acid Sphingomyelinase Protects From Severe Pathogen-Driven Colitis.
Topics: Amitriptyline; Animals; Biomarkers; Citrobacter rodentium; Colitis; Disease Models, Animal; Disease | 2019 |
Ischaemic colitis associated with psychotropic drugs.
Topics: Amitriptyline; Chlorpromazine; Colitis; Colon; Female; Humans; Ischemia; Middle Aged | 1984 |