amitriptyline has been researched along with Cirrhosis in 3 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| " treated ureterally obstructed mice with the tricyclic antidepressant amitriptyline and found that this inhibited inflammation, myofibroblast formation, and several other indices of renal fibrosis." | 7.75 | Pleiotropic effects of amitriptyline ameliorate renal fibrosis. ( Morrissey, JJ, 2009) |
| "Amitriptyline has recently been described as an analgesic, anti-inflammatory and myorelaxant in some experimental models." | 5.38 | Amitriptyline aggravates the fibrosis process in a rat model of infravesical obstruction. ( de Almeida Prado, PS; Lima, FO; Schor, N; Soares, MF; Teixeira, VP, 2012) |
| "Amitriptyline is a pleiotropic tricyclic antidepressant, which has anti-oxidant and anti-inflammatory properties." | 5.35 | Amitriptyline attenuates interstitial inflammation and ameliorates the progression of renal fibrosis. ( Achar, E; Collares, CF; Maciel, TT; Schor, N; Teixeira, VP, 2009) |
| " treated ureterally obstructed mice with the tricyclic antidepressant amitriptyline and found that this inhibited inflammation, myofibroblast formation, and several other indices of renal fibrosis." | 3.75 | Pleiotropic effects of amitriptyline ameliorate renal fibrosis. ( Morrissey, JJ, 2009) |
| "Amitriptyline has recently been described as an analgesic, anti-inflammatory and myorelaxant in some experimental models." | 1.38 | Amitriptyline aggravates the fibrosis process in a rat model of infravesical obstruction. ( de Almeida Prado, PS; Lima, FO; Schor, N; Soares, MF; Teixeira, VP, 2012) |
| "Amitriptyline is a pleiotropic tricyclic antidepressant, which has anti-oxidant and anti-inflammatory properties." | 1.35 | Amitriptyline attenuates interstitial inflammation and ameliorates the progression of renal fibrosis. ( Achar, E; Collares, CF; Maciel, TT; Schor, N; Teixeira, VP, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Achar, E | 1 |
| Maciel, TT | 1 |
| Collares, CF | 1 |
| Teixeira, VP | 2 |
| Schor, N | 2 |
| Morrissey, JJ | 1 |
| de Almeida Prado, PS | 1 |
| Soares, MF | 1 |
| Lima, FO | 1 |
3 other studies available for amitriptyline and Cirrhosis
| Article | Year |
|---|---|
Amitriptyline attenuates interstitial inflammation and ameliorates the progression of renal fibrosis.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Biomarkers; Cell Movement; Disease Progres | 2009 |
Pleiotropic effects of amitriptyline ameliorate renal fibrosis.
Topics: Amitriptyline; Animals; Fibroblasts; Fibrosis; Inflammation; Kidney Diseases; Mice | 2009 |
Amitriptyline aggravates the fibrosis process in a rat model of infravesical obstruction.
Topics: Amitriptyline; Animals; Disease Models, Animal; Fibrosis; Male; Rats; Rats, Wistar; Transforming Gro | 2012 |