amitriptyline has been researched along with Chronic Kidney Failure in 5 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "For trimipramine the AUC was significantly higher in patients." | 2.67 | [Comparative study of the pharmacokinetics of amitriptyline oxide and trimipramine after single administration in healthy male probands and patients with renal failure]. ( Degen, J; Fischer, W; Höxter, G; Pintar, P; Seiberling, M; Steinhauer, HB; Wölke, E, 1993) |
| "Pain is a hallmark of this condition and can be extremely difficult to control." | 1.56 | Pain management in patients with end-stage renal disease and calciphylaxis- a survey of clinical practices among physicians. ( Chinnadurai, R; Lowney, AC; Miller, M; Sinha, S, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chinnadurai, R | 1 |
| Sinha, S | 1 |
| Lowney, AC | 1 |
| Miller, M | 1 |
| Sandoz, M | 1 |
| Vandel, S | 1 |
| Vandel, B | 1 |
| Bonin, B | 1 |
| Hory, B | 1 |
| St Hillier, Y | 1 |
| Volmat, R | 1 |
| Degen, J | 1 |
| Wölke, E | 1 |
| Seiberling, M | 1 |
| Pintar, P | 1 |
| Höxter, G | 1 |
| Steinhauer, HB | 1 |
| Fischer, W | 1 |
| Rosser, R | 1 |
| Lieberman, JA | 1 |
| Cooper, TB | 1 |
| Suckow, RF | 1 |
| Steinberg, H | 1 |
| Borenstein, M | 1 |
| Brenner, R | 1 |
| Kane, JM | 1 |
1 trial available for amitriptyline and Chronic Kidney Failure
| Article | Year |
|---|---|
[Comparative study of the pharmacokinetics of amitriptyline oxide and trimipramine after single administration in healthy male probands and patients with renal failure].
Topics: Adult; Aged; Amitriptyline; Humans; Kidney Failure, Chronic; Male; Metabolic Clearance Rate; Middle | 1993 |
4 other studies available for amitriptyline and Chronic Kidney Failure
| Article | Year |
|---|---|
Pain management in patients with end-stage renal disease and calciphylaxis- a survey of clinical practices among physicians.
Topics: Acetaminophen; Advance Care Planning; Amitriptyline; Analgesics; Analgesics, Non-Narcotic; Analgesic | 2020 |
Metabolism of amitriptyline in patients with chronic renal failure.
Topics: Adult; Aged; Amitriptyline; Biotransformation; Depressive Disorder; Female; Humans; Kidney Failure, | 1984 |
Depression during renal dialysis and following transplantation.
Topics: Amitriptyline; Depression; Female; Humans; Kidney Failure, Chronic; Kidney Transplantation; Male; Mi | 1976 |
Tricyclic antidepressant and metabolite levels in chronic renal failure.
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Chromatography, Liquid; Depression; Desipramine; | 1985 |