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amitriptyline and Chorea

amitriptyline has been researched along with Chorea in 6 studies

Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.

Chorea: Involuntary, forcible, rapid, jerky movements that may be subtle or become confluent, markedly altering normal patterns of movement. Hypotonia and pendular reflexes are often associated. Conditions which feature recurrent or persistent episodes of chorea as a primary manifestation of disease are referred to as CHOREATIC DISORDERS. Chorea is also a frequent manifestation of BASAL GANGLIA DISEASES.

Research Excerpts

ExcerptRelevanceReference
"A 74-year-old woman developed a slowly progressive hemichorea starting 3 weeks after discontinuation of low-dose amitriptyline and perphenazine."7.67A case of progressive hemichorea responsive to high-dose reserpine. ( Friedman, JH, 1986)
"A 74-year-old woman developed a slowly progressive hemichorea starting 3 weeks after discontinuation of low-dose amitriptyline and perphenazine."3.67A case of progressive hemichorea responsive to high-dose reserpine. ( Friedman, JH, 1986)
"Haloperidol was implicated in 47 patients (37%), followed by amitriptyline/perphenazine in 30%, thioridazine in 27%, and chlorpromazine in 20%."1.28Neurologic approach to drug-induced movement disorders: a study of 125 patients. ( Jankovic, J; Miller, LG, 1990)
"A case of paroxysmal kinesigenic choreoathetosis is described."1.25Paroxysmal kinesigenic choreoathetosis. Report of a case relieved by L-dopa. ( Loong, SC; Ong, YY, 1973)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19905 (83.33)18.7374
1990's1 (16.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Holinger, PC1
Klawans, HL1
Miller, LG1
Jankovic, J1
Friedman, JH1
Markham, CH1
Burks, JS1
Walker, JE1
Rumack, BH1
Ott, JE1
Loong, SC1
Ong, YY1

Other Studies

6 other studies available for amitriptyline and Chorea

ArticleYear
Reversal of tricyclic-overdosage-induced central anticholinergic syndrome by physostigmine.
    The American journal of psychiatry, 1976, Volume: 133, Issue:9

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Athetosis; Chorea; Coma; Electroencephalography; Fe

1976
Neurologic approach to drug-induced movement disorders: a study of 125 patients.
    Southern medical journal, 1990, Volume: 83, Issue:5

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Amitriptyline; Antipsychotic Agents; Chorea

1990
A case of progressive hemichorea responsive to high-dose reserpine.
    The Journal of clinical psychiatry, 1986, Volume: 47, Issue:3

    Topics: Aged; Amitriptyline; Chorea; Dyskinesia, Drug-Induced; Female; Humans; Perphenazine; Reserpine; Subs

1986
The "on-off" side effect of L-DOPA.
    Advances in neurology, 1974, Volume: 5

    Topics: Age Factors; Amitriptyline; Aromatic Amino Acid Decarboxylase Inhibitors; Athetosis; Carbidopa; Cate

1974
Tricyclic antidepressant poisoning. Reversal of coma, choreoathetosis, and myoclonus by physostigmine.
    JAMA, 1974, Dec-04, Volume: 230, Issue:10

    Topics: Adult; Amitriptyline; Antidepressive Agents; Athetosis; Child, Preschool; Chorea; Coma; Female; Huma

1974
Paroxysmal kinesigenic choreoathetosis. Report of a case relieved by L-dopa.
    Journal of neurology, neurosurgery, and psychiatry, 1973, Volume: 36, Issue:6

    Topics: Adult; Amitriptyline; Athetosis; Chlordiazepoxide; Chorea; Dihydroxyphenylalanine; Humans; Male; Phe

1973