amitriptyline has been researched along with Cerebrovascular Disorders in 10 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Cerebrovascular Disorders: A spectrum of pathological conditions of impaired blood flow in the brain. They can involve vessels (ARTERIES or VEINS) in the CEREBRUM, the CEREBELLUM, and the BRAIN STEM. Major categories include INTRACRANIAL ARTERIOVENOUS MALFORMATIONS; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; and others.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A double-blind, 3-phase, cross-over, placebo-controlled trial of the pain-relieving effect of amitriptyline and carbamazepine was carried out in 15 patients with central post-stroke pain (CPSP) but without signs of depression." | 9.06 | Central post-stroke pain--a controlled trial of amitriptyline and carbamazepine. ( Boivie, J; Leijon, G, 1989) |
| "A double-blind, 3-phase, cross-over, placebo-controlled trial of the pain-relieving effect of amitriptyline and carbamazepine was carried out in 15 patients with central post-stroke pain (CPSP) but without signs of depression." | 5.06 | Central post-stroke pain--a controlled trial of amitriptyline and carbamazepine. ( Boivie, J; Leijon, G, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (80.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| SAINSBURY, MJ | 1 |
| Bach, O | 1 |
| Kästner, I | 1 |
| Shima, S | 1 |
| Colenda, CC | 1 |
| Leijon, G | 1 |
| Boivie, J | 1 |
| Ohkawa, S | 1 |
| Mori, E | 1 |
| Yamadori, A | 1 |
| Lawson, IR | 1 |
| MacLeod, RD | 1 |
| Gol'dovskaia, IL | 1 |
| Bots, GT | 1 |
| Dallos, V | 1 |
| Heathfield, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Management of Chronic Pain in Rehabilitation Project I - Management of Chronic Pain in Persons With Spinal Cord Injury[NCT00006428] | Phase 4 | 100 participants | Interventional | 1996-08-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 trials available for amitriptyline and Cerebrovascular Disorders
| Article | Year |
|---|---|
The efficacy of antidepressants in post-stroke depression.
Topics: Adult; Aged; Aged, 80 and over; Amitriptyline; Amoxapine; Antidepressive Agents, Tricyclic; Cerebrov | 1997 |
Central post-stroke pain--a controlled trial of amitriptyline and carbamazepine.
Topics: Aged; Amitriptyline; Carbamazepine; Cerebrovascular Disorders; Dose-Response Relationship, Drug; Dou | 1989 |
[Treatment of pathological laughing with amitriptyline].
Topics: Aged; Amitriptyline; Cerebrovascular Disorders; Clinical Trials as Topic; Double-Blind Method; Femal | 1989 |
The use of imipramine ("Tofranil") and other psychotropic drugs in organic emotionalism.
Topics: Affective Symptoms; Aged; Amitriptyline; Cerebrovascular Disorders; Clinical Trials as Topic; Female | 1969 |
6 other studies available for amitriptyline and Cerebrovascular Disorders
| Article | Year |
|---|---|
ELECTROPLEXY IN FIRST ATTACKS OF DEPRESSION OVER THE AGE OF FIFTY.
Topics: Amitriptyline; Bipolar Disorder; Cerebrovascular Disorders; Depression; Depressive Disorder; Drug Th | 1964 |
[Undesired drug side effects and drug-induced damage. II. Centrally acting drugs].
Topics: Adult; Amitriptyline; Autonomic Nervous System Diseases; Basal Ganglia Diseases; Central Nervous Sys | 1984 |
Antiarrhythmic properties of amitriptyline.
Topics: Aged; Amitriptyline; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bulbar Palsy, Progressive; Cerebr | 1990 |
[Ophthalmologic study of patients receiving psychotropic drugs].
Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents; Bipolar Disorder; Cataract; Cerebrova | 1970 |
Thrombosis of the galenic system veins in the adult.
Topics: Adult; Amitriptyline; Autopsy; Cerebral Hemorrhage; Cerebrovascular Disorders; Contraceptives, Oral; | 1971 |
Iatrogenic epilepsy due to antidepressant drugs.
Topics: Adolescent; Adult; Alcoholism; Amitriptyline; Antidepressive Agents; Barbiturates; Brain Damage, Chr | 1969 |