Page last updated: 2024-10-22

amitriptyline and Canine Diseases

amitriptyline has been researched along with Canine Diseases in 8 studies

Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.

Research Excerpts

ExcerptRelevanceReference
"Thirty-one dogs with nonlesional pruritus were treated with amitriptyline (1 mg/kg orally q12h) to determine its efficacy in the management of canine allergic pruritus."7.68Nonsteroidal management of canine pruritus with amitriptyline. ( Miller, WH; Scott, DW; Wellington, JR, 1992)
"Thirty-one dogs with nonlesional pruritus were treated with amitriptyline (1 mg/kg orally q12h) to determine its efficacy in the management of canine allergic pruritus."3.68Nonsteroidal management of canine pruritus with amitriptyline. ( Miller, WH; Scott, DW; Wellington, JR, 1992)
"This severe pain is mostly refractory to palliative analgesic treatment, and the latter was only detected by specific and sensitive outcomes."2.87Pain characterization and response to palliative care in dogs with naturally-occurring appendicular osteosarcoma: An open label clinical trial. ( Beauchamp, G; Blair, J; de Lorimier, LP; Lussier, B; Monteiro, BP; Moreau, M; Pelletier, JP; Troncy, E, 2018)
"Clomipramine was significantly more efficacious for treatment in dogs than was amitriptyline."1.31Clinical features and outcome in dogs and cats with obsessive-compulsive disorder: 126 cases (1989-2000). ( Dunham, AE; Overall, KL, 2002)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's2 (25.00)18.2507
2000's4 (50.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Monteiro, BP1
de Lorimier, LP1
Moreau, M1
Beauchamp, G1
Blair, J1
Lussier, B1
Pelletier, JP1
Troncy, E1
Bryant, SM1
Mycyk, MB1
Overall, KL3
Dunham, AE2
Reich, MR1
Ohad, DG1
Takeuchi, Y1
Houpt, KA1
Scarlett, JM1
Miller, WH1
Scott, DW1
Wellington, JR1
Frost, RC1

Trials

1 trial available for amitriptyline and Canine Diseases

ArticleYear
Pain characterization and response to palliative care in dogs with naturally-occurring appendicular osteosarcoma: An open label clinical trial.
    PloS one, 2018, Volume: 13, Issue:12

    Topics: Amitriptyline; Analgesics; Animals; Bone Neoplasms; Central Nervous System Sensitization; Dog Diseas

2018

Other Studies

7 other studies available for amitriptyline and Canine Diseases

ArticleYear
Human exposure to pet prescription medications.
    Veterinary and human toxicology, 2002, Volume: 44, Issue:4

    Topics: Acepromazine; Adult; Amitriptyline; Analgesics, Non-Narcotic; Animals; Dog Diseases; Dogs; Dopamine

2002
Clinical features and outcome in dogs and cats with obsessive-compulsive disorder: 126 cases (1989-2000).
    Journal of the American Veterinary Medical Association, 2002, Nov-15, Volume: 221, Issue:10

    Topics: Age of Onset; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Behavior Therapy; Behavior,

2002
Animal behavior case of the month. A dog was examined because of profound separation anxiety.
    Journal of the American Veterinary Medical Association, 1998, Jun-01, Volume: 212, Issue:11

    Topics: Acepromazine; Amitriptyline; Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Antipsy

1998
Electrocardiographic assessment of antianxiety medication in dogs and correlation with serum drug concentration.
    Journal of the American Veterinary Medical Association, 2000, May-15, Volume: 216, Issue:10

    Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Clomipramine; Dog Diseas

2000
Evaluation of treatments for separation anxiety in dogs.
    Journal of the American Veterinary Medical Association, 2000, Aug-01, Volume: 217, Issue:3

    Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Anxiety; Behavior Therapy; Behavior, Anima

2000
Nonsteroidal management of canine pruritus with amitriptyline.
    The Cornell veterinarian, 1992, Volume: 82, Issue:1

    Topics: Amitriptyline; Animals; Dermatitis, Atopic; Dog Diseases; Dogs; Female; Follow-Up Studies; Male; Pru

1992
Accidental poisoning of a dog with amitriptylline hydrochloride B. P.
    The Veterinary record, 1967, Dec-23, Volume: 81, Issue:26

    Topics: Amitriptyline; Animals; Dog Diseases; Dogs; Male

1967