amitriptyline has been researched along with Cancer of Colon in 2 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Preclinical studies have suggested that the long-term use of antidepressants may result in the initiation and/or promotion of tumor in the gastrointestinal tract." | 1.33 | Characterization of cytotoxic actions of tricyclic antidepressants on human HT29 colon carcinoma cells. ( Arimochi, H; Morita, K, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arimochi, H | 1 |
| Morita, K | 1 |
| Adams, S | 1 |
2 other studies available for amitriptyline and Cancer of Colon
| Article | Year |
|---|---|
Characterization of cytotoxic actions of tricyclic antidepressants on human HT29 colon carcinoma cells.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Apoptosis; Cell Cycle; Cell Proliferation; Cell Sur | 2006 |
Amitriptyline suppositories.
Topics: Amitriptyline; Colonic Neoplasms; Depression; Female; Humans; Middle Aged; Suppositories; Terminal C | 1982 |