amitriptyline has been researched along with Burns in 3 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Burns: Injuries to tissues caused by contact with heat, steam, chemicals (BURNS, CHEMICAL), electricity (BURNS, ELECTRIC), or the like.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Both amitriptylinetreatment and burn injury resulted in a 40% decrease of leukocyte Asm activity." | 1.43 | Amitriptyline Usage Exacerbates the Immune Suppression Following Burn Injury. ( Boone, KI; Caldwell, CC; Green, EA; Gulbins, E; Johnson, BL; Rice, TC; Xia, BT, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Johnson, BL | 1 |
| Rice, TC | 1 |
| Xia, BT | 1 |
| Boone, KI | 1 |
| Green, EA | 1 |
| Gulbins, E | 1 |
| Caldwell, CC | 1 |
| Oatway, M | 1 |
| Reid, A | 1 |
| Sawynok, J | 1 |
| Crompton, DR | 1 |
| Pegg, SP | 1 |
| Jellett, LB | 1 |
| Middleton, W | 1 |
3 other studies available for amitriptyline and Burns
| Article | Year |
|---|---|
Amitriptyline Usage Exacerbates the Immune Suppression Following Burn Injury.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Blotting, Western; Burns; Chemokines; Cyto | 2016 |
Peripheral antihyperalgesic and analgesic actions of ketamine and amitriptyline in a model of mild thermal injury in the rat.
Topics: Administration, Topical; Amitriptyline; Anesthetics, Dissociative; Animals; Antidepressive Agents, T | 2003 |
Altered pharmacokinetics of tricyclic antidepressants in burns.
Topics: Adult; Amitriptyline; Burns; Depressive Disorder; Dose-Response Relationship, Drug; Female; Humans; | 1991 |