Page last updated: 2024-10-22

amitriptyline and Bruxism

amitriptyline has been researched along with Bruxism in 2 studies

Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.

Bruxism: A disorder characterized by grinding and clenching of the teeth.

Research Excerpts

ExcerptRelevanceReference
"Using a double-blind and randomized experimental design, ten adult subjects with sleep bruxism were administered amitriptyline (25 mg/night) and placebo (25 mg/night), each compound over a period of one week."9.08A randomized double-blind clinical trial of the effect of amitriptyline on nocturnal masseteric motor activity (sleep bruxism). ( Christensen, LV; Mohamed, SE; Penchas, J, 1997)
"Using a double-blind and randomized experimental design, ten adult subjects with sleep bruxism were administered amitriptyline (25 mg/night) and placebo (25 mg/night), each compound over a period of one week."5.08A randomized double-blind clinical trial of the effect of amitriptyline on nocturnal masseteric motor activity (sleep bruxism). ( Christensen, LV; Mohamed, SE; Penchas, J, 1997)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mohamed, SE1
Christensen, LV1
Penchas, J1
Melis, M1

Trials

1 trial available for amitriptyline and Bruxism

ArticleYear
A randomized double-blind clinical trial of the effect of amitriptyline on nocturnal masseteric motor activity (sleep bruxism).
    Cranio : the journal of craniomandibular practice, 1997, Volume: 15, Issue:4

    Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Bruxism; Double-Blind Method; Electromyograp

1997

Other Studies

1 other study available for amitriptyline and Bruxism

ArticleYear
Dr. Melis comments on Raigrodski, et al.'s article in the January 2001 issue of CRANIO.
    Cranio : the journal of craniomandibular practice, 2001, Volume: 19, Issue:3

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Bruxism; Electromyography; Humans; Masseter Muscle;

2001