Page last updated: 2024-10-22

amitriptyline and Bruxism, Nocturnal

amitriptyline has been researched along with Bruxism, Nocturnal in 3 studies

Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.

Research Excerpts

ExcerptRelevanceReference
"Sleep bruxism is an oral activity characterized by involuntary teeth grinding or clenching during sleep."2.50Pharmacotherapy for sleep bruxism. ( Macedo, CR; Macedo, EC; Prado, GF; Silva, AB; Torloni, MR, 2014)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Macedo, CR1
Macedo, EC1
Torloni, MR1
Silva, AB1
Prado, GF1
Raigrodski, AJ2
Mohamed, SE2
Gardiner, DM2
Christensen, LV1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
OstiSense Biosensor in Bruxism Reduction - A Clinical Study[NCT03749928]0 participants (Actual)Interventional2021-12-31Withdrawn (stopped due to Study was not funded)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for amitriptyline and Bruxism, Nocturnal

ArticleYear
Pharmacotherapy for sleep bruxism.
    The Cochrane database of systematic reviews, 2014, Oct-23, Issue:10

    Topics: Amitriptyline; Bromocriptine; Clonidine; Humans; Levodopa; Propranolol; Randomized Controlled Trials

2014

Trials

2 trials available for amitriptyline and Bruxism, Nocturnal

ArticleYear
The effect of amitriptyline on pain intensity and perception of stress in bruxers.
    Journal of prosthodontics : official journal of the American College of Prosthodontists, 2001, Volume: 10, Issue:2

    Topics: Amitriptyline; Analysis of Variance; Antidepressive Agents, Tricyclic; Cross-Over Studies; Double-Bl

2001
The effect of four-week administration of amitriptyline on sleep bruxism. A double-blind crossover clinical study.
    Cranio : the journal of craniomandibular practice, 2001, Volume: 19, Issue:1

    Topics: Adult; Amitriptyline; Analysis of Variance; Antidepressive Agents, Tricyclic; Cross-Over Studies; Do

2001