amitriptyline has been researched along with Breast Neoplasms in 12 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Breast Neoplasms: Tumors or cancer of the human BREAST.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this double-blind, non-placebo controlled study [corrected], 179 patients with treated breast cancer who fulfilled the ICD-10 criteria for an acute depressive episode underwent an 8-week course of antidepressant treatment with either the tricyclic amitriptyline (75-150 mg, n = 87) or the serotonin-reuptake inhibitor paroxetine (20-40 mg, n = 88)." | 9.09 | [A double-blind comparative study of the effectiveness and tolerance of paroxetine and amitriptyline in treatment of breast cancer patients with clinically assessed depression]. ( Contu, A; Gutschow, K; Möslinger-Gehmayr, R; Oberhoff, C; Schindler, AE; Staab, HJ; Zaninelli, R, 2000) |
| "The effectiveness of amitriptyline in relieving neuropathic pain following treatment of breast cancer was studied in 15 patients in a randomised, double-blind placebo-controlled crossover study." | 9.08 | Amitriptyline effectively relieves neuropathic pain following treatment of breast cancer. ( Eija, K; J, NP; Tiina, T, 1996) |
| "In this double-blind, non-placebo controlled study [corrected], 179 patients with treated breast cancer who fulfilled the ICD-10 criteria for an acute depressive episode underwent an 8-week course of antidepressant treatment with either the tricyclic amitriptyline (75-150 mg, n = 87) or the serotonin-reuptake inhibitor paroxetine (20-40 mg, n = 88)." | 5.09 | [A double-blind comparative study of the effectiveness and tolerance of paroxetine and amitriptyline in treatment of breast cancer patients with clinically assessed depression]. ( Contu, A; Gutschow, K; Möslinger-Gehmayr, R; Oberhoff, C; Schindler, AE; Staab, HJ; Zaninelli, R, 2000) |
| "The effectiveness of amitriptyline in relieving neuropathic pain following treatment of breast cancer was studied in 15 patients in a randomised, double-blind placebo-controlled crossover study." | 5.08 | Amitriptyline effectively relieves neuropathic pain following treatment of breast cancer. ( Eija, K; J, NP; Tiina, T, 1996) |
| " Treatment with oral contraceptive (OC) for endometriosis and later with cyclophosphamide, methotrexate, fluorouracil (CMF) for breast cancer produced a higher number of attacks." | 3.74 | Influence of physiologic hormonal modification and of hormonal treatment in a patient with a history of migraine with aura. ( Maggioni, F; Palmieri, A; Tropea, M; Zanchin, G, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (25.00) | 18.7374 |
| 1990's | 4 (33.33) | 18.2507 |
| 2000's | 4 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Lei, B | 1 |
| Xu, L | 1 |
| Zhang, X | 1 |
| Peng, W | 1 |
| Tang, Q | 1 |
| Feng, C | 1 |
| Makino, H | 1 |
| Maggioni, F | 1 |
| Palmieri, A | 1 |
| Tropea, M | 1 |
| Zanchin, G | 1 |
| de Levin, RW | 1 |
| Puig, OR | 1 |
| Levin, E | 1 |
| Freilich, RJ | 1 |
| Seidman, AD | 1 |
| Eija, K | 1 |
| Tiina, T | 1 |
| J, NP | 1 |
| Möslinger-Gehmayr, R | 2 |
| Zaninelli, R | 1 |
| Contu, A | 2 |
| Oberhoff, C | 1 |
| Gutschow, K | 1 |
| Schindler, AE | 1 |
| Staab, HJ | 1 |
| Tasmuth, T | 1 |
| von Smitten, K | 1 |
| Blomqvist, C | 1 |
| Kalso, E | 1 |
| Pezzella, G | 1 |
| Marx, J | 1 |
| Reinhardt, U | 1 |
| Maguire, P | 1 |
| Hopwood, P | 1 |
| Tarrier, N | 1 |
| Howell, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| "A Prospective, Randomized Study of the Possible Pain Relieving and Scar Tissue Modifying Properties of Lipotransplantation in a Post Breast Therapy Pain Syndrome Setting"[NCT01888419] | 18 participants (Actual) | Interventional | 2014-10-31 | Completed | |||
| Comparative Evaluation of Osteopathy Treatment Efficacy in Pain Support After Breast Surgery in Oncology[NCT01403168] | 28 participants (Actual) | Interventional | 2011-04-30 | Terminated (stopped due to Recruitment difficulties) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for amitriptyline and Breast Neoplasms
| Article | Year |
|---|---|
Treatment and care of neurotoxicity from taxane anticancer agents.
Topics: Amino Acids; Amitriptyline; Antidepressive Agents, Tricyclic; Antineoplastic Agents, Phytogenic; Bre | 2004 |
6 trials available for amitriptyline and Breast Neoplasms
| Article | Year |
|---|---|
Pruritus caused by 3-hour infusion of high-dose paclitaxel and improvement with tricyclic antidepressants.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Breast Neoplasms; Humans; Infusions, Intravenous; N | 1995 |
Amitriptyline effectively relieves neuropathic pain following treatment of breast cancer.
Topics: Adult; Aged; Amitriptyline; Analgesics, Non-Narcotic; Anxiety; Breast Neoplasms; Cross-Over Studies; | 1996 |
Amitriptyline effectively relieves neuropathic pain following treatment of breast cancer.
Topics: Adult; Aged; Amitriptyline; Analgesics, Non-Narcotic; Anxiety; Breast Neoplasms; Cross-Over Studies; | 1996 |
Amitriptyline effectively relieves neuropathic pain following treatment of breast cancer.
Topics: Adult; Aged; Amitriptyline; Analgesics, Non-Narcotic; Anxiety; Breast Neoplasms; Cross-Over Studies; | 1996 |
Amitriptyline effectively relieves neuropathic pain following treatment of breast cancer.
Topics: Adult; Aged; Amitriptyline; Analgesics, Non-Narcotic; Anxiety; Breast Neoplasms; Cross-Over Studies; | 1996 |
[A double-blind comparative study of the effectiveness and tolerance of paroxetine and amitriptyline in treatment of breast cancer patients with clinically assessed depression].
Topics: Adaptation, Psychological; Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents, Second-Gen | 2000 |
[Chronic pain and other symptoms following treatment of breast cancer].
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Breast Neoplasms; Cross-Over Studies; Double-Blind | 1998 |
Treatment of depression in patients with breast cancer: a comparison between paroxetine and amitriptyline.
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricycl | 2001 |
Treatment of depression in cancer patients.
Topics: Amitriptyline; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Depression; Fe | 1985 |
5 other studies available for amitriptyline and Breast Neoplasms
| Article | Year |
|---|---|
The proliferation effects of fluoxetine and amitriptyline on human breast cancer cells and the underlying molecular mechanisms.
Topics: Amitriptyline; Antidepressive Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell S | 2021 |
Influence of physiologic hormonal modification and of hormonal treatment in a patient with a history of migraine with aura.
Topics: Amitriptyline; Analgesics; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Pro | 2008 |
Increased risk for cancer of the breast due to previous medication.
Topics: 20-alpha-Dihydroprogesterone; Adult; Aged; Amitriptyline; Amphetamines; Breast Neoplasms; Cimetidine | 1984 |
Do antidepressants promote tumors?
Topics: Amitriptyline; Animals; Breast Neoplasms; Carcinogens; Female; Fluoxetine; Humans; Mice; Neoplasms, | 1992 |
[Modification of tumor pain by psychotropic drugs].
Topics: Adult; Aged; Amitriptyline; Bone Neoplasms; Breast Neoplasms; Chlorprothixene; Drug Therapy, Combina | 1987 |