Page last updated: 2024-10-22

amitriptyline and Brain Vascular Disorders

amitriptyline has been researched along with Brain Vascular Disorders in 10 studies

Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.

Research Excerpts

ExcerptRelevanceReference
"A double-blind, 3-phase, cross-over, placebo-controlled trial of the pain-relieving effect of amitriptyline and carbamazepine was carried out in 15 patients with central post-stroke pain (CPSP) but without signs of depression."9.06Central post-stroke pain--a controlled trial of amitriptyline and carbamazepine. ( Boivie, J; Leijon, G, 1989)
"A double-blind, 3-phase, cross-over, placebo-controlled trial of the pain-relieving effect of amitriptyline and carbamazepine was carried out in 15 patients with central post-stroke pain (CPSP) but without signs of depression."5.06Central post-stroke pain--a controlled trial of amitriptyline and carbamazepine. ( Boivie, J; Leijon, G, 1989)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19908 (80.00)18.7374
1990's2 (20.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
SAINSBURY, MJ1
Bach, O1
Kästner, I1
Shima, S1
Colenda, CC1
Leijon, G1
Boivie, J1
Ohkawa, S1
Mori, E1
Yamadori, A1
Lawson, IR1
MacLeod, RD1
Gol'dovskaia, IL1
Bots, GT1
Dallos, V1
Heathfield, K1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Management of Chronic Pain in Rehabilitation Project I - Management of Chronic Pain in Persons With Spinal Cord Injury[NCT00006428]Phase 4100 participants Interventional1996-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

4 trials available for amitriptyline and Brain Vascular Disorders

ArticleYear
The efficacy of antidepressants in post-stroke depression.
    The Keio journal of medicine, 1997, Volume: 46, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Amitriptyline; Amoxapine; Antidepressive Agents, Tricyclic; Cerebrov

1997
Central post-stroke pain--a controlled trial of amitriptyline and carbamazepine.
    Pain, 1989, Volume: 36, Issue:1

    Topics: Aged; Amitriptyline; Carbamazepine; Cerebrovascular Disorders; Dose-Response Relationship, Drug; Dou

1989
[Treatment of pathological laughing with amitriptyline].
    Rinsho shinkeigaku = Clinical neurology, 1989, Volume: 29, Issue:9

    Topics: Aged; Amitriptyline; Cerebrovascular Disorders; Clinical Trials as Topic; Double-Blind Method; Femal

1989
The use of imipramine ("Tofranil") and other psychotropic drugs in organic emotionalism.
    The British journal of psychiatry : the journal of mental science, 1969, Volume: 115, Issue:520

    Topics: Affective Symptoms; Aged; Amitriptyline; Cerebrovascular Disorders; Clinical Trials as Topic; Female

1969

Other Studies

6 other studies available for amitriptyline and Brain Vascular Disorders

ArticleYear
ELECTROPLEXY IN FIRST ATTACKS OF DEPRESSION OVER THE AGE OF FIFTY.
    The Medical journal of Australia, 1964, Jun-20, Volume: 1

    Topics: Amitriptyline; Bipolar Disorder; Cerebrovascular Disorders; Depression; Depressive Disorder; Drug Th

1964
[Undesired drug side effects and drug-induced damage. II. Centrally acting drugs].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1984, Jan-01, Volume: 39, Issue:1

    Topics: Adult; Amitriptyline; Autonomic Nervous System Diseases; Basal Ganglia Diseases; Central Nervous Sys

1984
Antiarrhythmic properties of amitriptyline.
    Southern medical journal, 1990, Volume: 83, Issue:4

    Topics: Aged; Amitriptyline; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bulbar Palsy, Progressive; Cerebr

1990
[Ophthalmologic study of patients receiving psychotropic drugs].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1970, Volume: 70, Issue:5

    Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents; Bipolar Disorder; Cataract; Cerebrova

1970
Thrombosis of the galenic system veins in the adult.
    Acta neuropathologica, 1971, Volume: 17, Issue:3

    Topics: Adult; Amitriptyline; Autopsy; Cerebral Hemorrhage; Cerebrovascular Disorders; Contraceptives, Oral;

1971
Iatrogenic epilepsy due to antidepressant drugs.
    British medical journal, 1969, Oct-11, Volume: 4, Issue:5675

    Topics: Adolescent; Adult; Alcoholism; Amitriptyline; Antidepressive Agents; Barbiturates; Brain Damage, Chr

1969