amitriptyline has been researched along with Brain Neoplasms in 6 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In the present study, we investigated the effects of chronic in vitro administration of amitriptyline, a tricyclic antidepressant, on cyclic GMP formation stimulated by 5-hydroxytryptamine (5-HT) in the neuroblastoma x glioma hybrid cell line, NG 108-15, 5-HT (0." | 3.69 | Chronic amitriptyline exposure reduces 5-HT3 receptor-mediated cyclic GMP formation in NG 108-15 cells. ( Nishida, A; Shimizu, M; Yamawaki, S; Zensho, H, 1996) |
| "In this investigation the effects of tricyclic drugs on cellular respiration were studied using the anaplastic astrocytoma cell line IPSB-18 by use of a Clark-type oxygen electrode which measured changes in cellular respiration rate (oxygen consumption), in a dose-response assay." | 1.36 | The in vitro effects of tricyclic drugs and dexamethasone on cellular respiration of malignant glioma. ( Higgins, SC; Pilkington, GJ, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Higgins, SC | 1 |
| Pilkington, GJ | 1 |
| Koval'chuk, VV | 1 |
| Khouzam, HR | 1 |
| Emery, PE | 1 |
| Reaves, B | 1 |
| Shimizu, M | 1 |
| Nishida, A | 1 |
| Zensho, H | 1 |
| Yamawaki, S | 1 |
| Glötzner, FL | 1 |
| Samland, O | 1 |
| Dommasch, D | 1 |
| Blinder, MG | 1 |
1 trial available for amitriptyline and Brain Neoplasms
| Article | Year |
|---|---|
[Pharmacologic correction of psycho-emotive disorders in the rehabilitation of patients after removal of brain tumors].
Topics: Adult; Alprazolam; Amitriptyline; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Brain Neoplas | 2007 |
5 other studies available for amitriptyline and Brain Neoplasms
| Article | Year |
|---|---|
The in vitro effects of tricyclic drugs and dexamethasone on cellular respiration of malignant glioma.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Antineoplastic Agents, Hormonal; Antineoplastic Com | 2010 |
Secondary mania in late life.
Topics: Age Factors; Aged; Amitriptyline; Bipolar Disorder; Brain Neoplasms; Diagnosis, Differential; Female | 1994 |
Chronic amitriptyline exposure reduces 5-HT3 receptor-mediated cyclic GMP formation in NG 108-15 cells.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Benzamides; Bradykinin; Brain Neoplasms; Bridged Bi | 1996 |
[Brain stem seizures with circumscrbed elementary symptoms].
Topics: Adult; Amitriptyline; Ataxia; Brain Neoplasms; Brain Stem; Carbamazepine; Epilepsy; Female; Humans; | 1976 |
Classification and treatment of depression.
Topics: Adjustment Disorders; Amitriptyline; Anxiety; Bipolar Disorder; Brain Neoplasms; Depression; Histrio | 1969 |