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amitriptyline and Brain Disorders

amitriptyline has been researched along with Brain Disorders in 14 studies

Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.

Research Excerpts

ExcerptRelevanceReference
"This report describes a case of encephalopathy developed in the course of amitriptyline therapy, during a remission of unipolar depression."5.29Encephalopathy during amitriptyline therapy: are neuroleptic malignant syndrome and serotonin syndrome spectrum disorders? ( Kamijima, K; Miyaoka, H, 1995)
" We investigated the efficacy of low-dose amitriptyline in 12 patients in whom this syndrome was a consequence of multiple sclerosis."5.05Treatment of pathologic laughing and weeping with amitriptyline. ( Herndon, RM; Rudick, RA; Schiffer, RB, 1985)
"This report describes a case of encephalopathy developed in the course of amitriptyline therapy, during a remission of unipolar depression."1.29Encephalopathy during amitriptyline therapy: are neuroleptic malignant syndrome and serotonin syndrome spectrum disorders? ( Kamijima, K; Miyaoka, H, 1995)
" Moreover, the endocrine and behavioral deficits of bulbectomized rats are reversed by the chronic administration of drugs that reverse the symptoms of depression in people when given chronically."1.27Effects of antidepressant drugs on the behavior of olfactory bulbectomized and sham-operated rats. ( Jesberger, JA; Richardson, JS, 1986)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-199010 (71.43)18.7374
1990's2 (14.29)18.2507
2000's1 (7.14)29.6817
2010's1 (7.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mohammed, A1
Sheikh, TL1
Gidado, S1
Abdus-Salam, IA1
Adeyemi, J1
Olayinka, A1
Ohuabunwo, C1
Victor, OO1
Nguku, P1
Rasheed, EA1
Doherty, F1
Waziri, N1
Shuaib, F1
Joseph, BO1
Bomai, IM1
Oyemakinde, A1
KANE, FJ1
TAYLOR, TW1
MARIANI, E1
VELLA, G1
WITTON, K1
KRUEGER, H1
ZUMPE, V1
Small, JG1
Small, IF1
Sabet, LM1
Brañas Fernández, F1
Cortés Laiño, JA1
Martínez Vázquez, F1
Rabuñal Rey, R1
Miyaoka, H1
Kamijima, K1
Yaryura-Tobias, JA1
Pinto, A1
Neziroglu, F1
Niss, AI1
Trubkovich, MIa1
Schiffer, RB1
Herndon, RM1
Rudick, RA1
Jesberger, JA1
Richardson, JS1
Nievoll, A1

Trials

1 trial available for amitriptyline and Brain Disorders

ArticleYear
Treatment of pathologic laughing and weeping with amitriptyline.
    The New England journal of medicine, 1985, Jun-06, Volume: 312, Issue:23

    Topics: Adult; Aged; Amitriptyline; Brain Diseases; Clinical Trials as Topic; Crying; Double-Blind Method; F

1985

Other Studies

13 other studies available for amitriptyline and Brain Disorders

ArticleYear
Psychiatric treatment of a health care worker after infection with Ebola virus in Lagos, Nigeria.
    The American journal of psychiatry, 2015, Mar-01, Volume: 172, Issue:3

    Topics: Adjustment Disorders; Amitriptyline; Antidepressive Agents, Tricyclic; Behavioral Symptoms; Brain Di

2015
A toxic reaction to combined Elavil-Librium therapy.
    The American journal of psychiatry, 1963, Volume: 119

    Topics: Amitriptyline; Antidepressive Agents; Brain Diseases; Cerebellar Diseases; Chlordiazepoxide; Postope

1963
[CLINICAL CONSIDERATIONS ON A CASE OF MANIC-DEPRESSIVE PSYCHOSIS IN MIDDLE AGE, WITH CORTICAL ATROPHY AND INTELLECTUAL DETERIORATION].
    Rivista sperimentale di freniatria e medicina legale delle alienazioni mentali, 1963, Dec-31, Volume: 87

    Topics: Amitriptyline; Atrophy; Bipolar Disorder; Brain Diseases; Cerebral Cortex; Humans; Imipramine; Memor

1963
SEVERE TOXIC REACTION TO COMBINED AMITRIPTYLINE AND THIORIDAZINE.
    The American journal of psychiatry, 1965, Volume: 121

    Topics: Amitriptyline; Bipolar Disorder; Brain Diseases; Catatonia; Coma; Diagnosis, Differential; Drug Syne

1965
[AMITRYPTILINE POISONING. A CONTRIBUTION TO THE CLINICAL PICTURE. PSYCHIATRIC AND PSYCHOLOGICAL TEST STUDIES ON THE PROBLEM OF THE TOXIC BRAIN DEGERERATION SYNDROME].
    Der Nervenarzt, 1965, Volume: 36

    Topics: Amitriptyline; Antidepressive Agents; Brain; Brain Damage, Chronic; Brain Diseases; Brain Injuries;

1965
EEG spikes in non-epileptic psychiatric patients.
    Diseases of the nervous system, 1967, Volume: 28, Issue:8

    Topics: Adolescent; Adult; Aged; Amitriptyline; Antisocial Personality Disorder; Barbiturates; Brain; Brain

1967
Bilateral symmetrical brain lesions in tricyclic antidepressant overdosage.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1980, Volume: 7, Issue:4

    Topics: Adult; Amitriptyline; Brain; Brain Diseases; Cerebral Hemorrhage; Corpus Striatum; Female; Globus Pa

1980
[Transitory algic hemilateral syndrome in relation to spontaneous lobar hematoma].
    Neurologia (Barcelona, Spain), 1993, Volume: 8, Issue:9

    Topics: Aged; Amitriptyline; Brain; Brain Diseases; Functional Laterality; Headache; Hematoma; Humans; Male;

1993
Encephalopathy during amitriptyline therapy: are neuroleptic malignant syndrome and serotonin syndrome spectrum disorders?
    International clinical psychopharmacology, 1995, Volume: 10, Issue:4

    Topics: Amitriptyline; Brain Diseases; Depressive Disorder; Follow-Up Studies; Humans; Male; Middle Aged; Ne

1995
Anorexia nervosa, diabetes mellitus, brain atrophy, and fatty liver.
    The International journal of eating disorders, 2001, Volume: 30, Issue:3

    Topics: Adult; Amitriptyline; Anorexia Nervosa; Antidepressive Agents, Tricyclic; Behavior Therapy; Brain Di

2001
[Various rarely encountered adverse effects and complications of psychopharmacotherapy].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1985, Volume: 85, Issue:5

    Topics: Adult; Agnosia; Amitriptyline; Apraxias; Brain Diseases; Cerebral Cortex; Haloperidol; Humans; Male;

1985
Effects of antidepressant drugs on the behavior of olfactory bulbectomized and sham-operated rats.
    Behavioral neuroscience, 1986, Volume: 100, Issue:2

    Topics: 11-Hydroxycorticosteroids; Amitriptyline; Animals; Antidepressive Agents; Brain Diseases; Depressive

1986
[Therapeutic experiences with oxazepam--a derivative of the benzodiazepine series--in child and adolescent psychiatry].
    Wiener klinische Wochenschrift, 1971, Apr-09, Volume: 83, Issue:14

    Topics: Adolescent; Adolescent Psychiatry; Adult; Aggression; Amitriptyline; Anticonvulsants; Brain Damage,

1971