amitriptyline has been researched along with Blood Pressure, High in 38 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Current pharmacotherapies for PTSD manage only a subset of these symptoms and typically have adverse side effects which limit their overall effectiveness." | 5.39 | Differential effectiveness of tianeptine, clonidine and amitriptyline in blocking traumatic memory expression, anxiety and hypertension in an animal model of PTSD. ( Diamond, DM; Fleshner, M; Zoladz, PR, 2013) |
| " The workup included an endocrinological examination, which revealed a moderately elevated urine normetanephrine level, suggesting the possibility of a pheochromocytoma." | 3.80 | Obstructive sleep apnea and tricyclic antidepressant use presenting as a pseudopheochromocytoma in an active duty sailor: a case report. ( Brainard, T, 2014) |
| " Patients with an amitriptyline overdose were more likely to have seizure, coma, tachycardia, a wide QRS or ventricular dysrhythmia, and have received sodium bicarbonate or be intubated." | 3.77 | Incidence of tricyclic antidepressant-like complications after cyclobenzaprine overdose. ( Bebarta, VS; Borys, DJ; Maddry, J; Morgan, DL, 2011) |
| " The case presentation illustrates the role of pregabalin in successful medical management of this chronic pain disorder, as well as the management of common psychiatric morbidities associated with this condition." | 3.74 | Pregabalin-induced remission in a 62-year-old woman with a 20-year history of vulvodynia. ( Jerome, L, 2007) |
| "The analysis of variance and Student's "t" test were applied in an assessment of the hypotensive effectiveness of three hypotensive protocols: a) diazepam + amitryptiline; b) reserpine + chlorthalidone; c) all drugs in 57 and 32 patients with stabilised essential hypertension." | 3.66 | [Clinical and statistical evaluation of the hypotensive effectiveness of 3 therapeutic plans in essential hypertension]. ( D'Amelio, G; Menozzi, L; Piccoli, A, 1978) |
| "The tricyclic antidepressant drugs: imipramine, opipramol, amitryptiline and nortryptiline inhibit development of experimental arterial hypertension in rats." | 3.65 | Influence of tricyclic antidepressant drugs on experimental arterial hypertension. ( Bobkiewicz, T; Chodera, A; Nowakowska, E; Okulicz-Kozaryn, I, 1975) |
| "Sixty patients meeting DSM-III criteria for major depression were assigned randomly to double-blind treatment for four weeks according to fixed-dosage steps with (1) amitriptyline hydrochloride alone, up to a maximum dosage of 300 mg/day; (2) tranylcypromine alone, up to 40 mg/day; or (3) the combination of amitriptyline hydrochloride, up to 150 mg/day, and tranylcypromine, up to 20 mg/day." | 2.65 | The safety and efficacy of combined amitriptyline and tranylcypromine antidepressant treatment. A controlled trial. ( Palmer, R; Razani, J; Rebal, R; Simpson, G; Sloane, RB; White, J; White, KL, 1983) |
| "Current pharmacotherapies for PTSD manage only a subset of these symptoms and typically have adverse side effects which limit their overall effectiveness." | 1.39 | Differential effectiveness of tianeptine, clonidine and amitriptyline in blocking traumatic memory expression, anxiety and hypertension in an animal model of PTSD. ( Diamond, DM; Fleshner, M; Zoladz, PR, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 30 (78.95) | 18.7374 |
| 1990's | 3 (7.89) | 18.2507 |
| 2000's | 2 (5.26) | 29.6817 |
| 2010's | 3 (7.89) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brainard, T | 1 |
| Bebarta, VS | 1 |
| Maddry, J | 1 |
| Borys, DJ | 1 |
| Morgan, DL | 1 |
| Zoladz, PR | 1 |
| Fleshner, M | 1 |
| Diamond, DM | 1 |
| BATTERMAN, RC | 1 |
| KAUFMAN, JE | 1 |
| MOURATOFF, GJ | 1 |
| WHITE, AG | 1 |
| Jerome, L | 1 |
| Arnold, G | 1 |
| Schuh-Hofer, S | 1 |
| Schmitt, H | 2 |
| Pare, CM | 2 |
| Kline, N | 1 |
| Hallstrom, C | 1 |
| Cooper, TB | 1 |
| Razani, J | 1 |
| White, KL | 1 |
| White, J | 1 |
| Simpson, G | 1 |
| Sloane, RB | 1 |
| Rebal, R | 1 |
| Palmer, R | 1 |
| Stiff, JL | 1 |
| Harris, DB | 1 |
| Sim, MK | 1 |
| Ratnam, KV | 1 |
| Silas, JH | 1 |
| Tucker, GT | 1 |
| Smith, AJ | 2 |
| Fieller, NR | 1 |
| Zedkova, L | 1 |
| Coupland, NJ | 1 |
| Burgess, CD | 1 |
| Turner, P | 1 |
| Wadsworth, J | 1 |
| Chodera, A | 2 |
| Konkiewicz, B | 1 |
| Nowakowska, E | 2 |
| Godlewski, J | 1 |
| D'Amelio, G | 1 |
| Piccoli, A | 1 |
| Menozzi, L | 1 |
| Rampton, DS | 1 |
| Spiker, DG | 1 |
| Pugh, DD | 1 |
| Bobkiewicz, T | 1 |
| Okulicz-Kozaryn, I | 1 |
| Buckley, M | 1 |
| Feely, J | 1 |
| Zajecka, J | 1 |
| Fawcett, J | 1 |
| Babb, SV | 1 |
| Dunlop, SR | 1 |
| Ogura, C | 1 |
| Kimishima, K | 1 |
| Sweet, RL | 1 |
| Sheffield, LT | 1 |
| Lajeunesse, BS | 1 |
| Lamarche, M | 1 |
| Royer, R | 1 |
| Heisel, J | 1 |
| Turkington, RW | 1 |
| Gayral, LF | 1 |
| Drotar, D | 1 |
| Kilpatrick, R | 1 |
| Lance, JW | 1 |
| Curran, DA | 1 |
| Anthony, M | 1 |
| Meyer, JF | 1 |
| McAllister, CK | 1 |
| Goldberg, LI | 1 |
| Schuckit, M | 1 |
| Robins, E | 1 |
| Feighner, J | 1 |
| Marino, A | 2 |
| Colucci D'Amato, F | 1 |
| Miracco, A | 1 |
| De Marino, V | 1 |
| Witton, K | 1 |
3 reviews available for amitriptyline and Blood Pressure, High
| Article | Year |
|---|---|
[Comorbidities in migraine patients].
Topics: Adult; Amitriptyline; Analgesics, Non-Narcotic; Anticonvulsants; Anxiety Disorders; Carotid Artery, | 2007 |
New pharmacological developments in antidepressants.
Topics: Amitriptyline; Drug Interactions; Humans; Hypertension; Monoamine Oxidase Inhibitors; Piperidines; T | 1986 |
Advances in medicine.
Topics: Amitriptyline; Cholera; Coronary Disease; Crohn Disease; Diabetes Mellitus; Diet Therapy; Diverticul | 1971 |
5 trials available for amitriptyline and Blood Pressure, High
| Article | Year |
|---|---|
The safety and efficacy of combined amitriptyline and tranylcypromine antidepressant treatment. A controlled trial.
Topics: Adult; Amitriptyline; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Drug Thera | 1983 |
Accumulation of debrisoquine by platelets in vivo: a model of events at the peripheral adrenergic neurone.
Topics: Amitriptyline; Blood Platelets; Debrisoquin; Erythrocytes; Humans; Hydroxylation; Hypertension; Isoq | 1980 |
Cardiovascular responses to mianserin hydrochloride: a comparison with tricyclic antidepressant drugs.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Bethanidine; Blood Pressure; Cardiovascular | 1978 |
Prolactin secretion in patients treated with various drugs: phenothiazines, tricyclic antidepressants, reserpine, and methyldopa.
Topics: Amitriptyline; Antidepressive Agents; Chlorpromazine; Clinical Trials as Topic; Fluphenazine; Humans | 1972 |
Investigations into the mechanism and treatment of chronic headache.
Topics: Amitriptyline; Clinical Trials as Topic; Headache; Humans; Hydroxyindoleacetic Acid; Hypertension; M | 1965 |
30 other studies available for amitriptyline and Blood Pressure, High
| Article | Year |
|---|---|
Obstructive sleep apnea and tricyclic antidepressant use presenting as a pseudopheochromocytoma in an active duty sailor: a case report.
Topics: Adrenal Gland Neoplasms; Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Diagnosis, Differen | 2014 |
Incidence of tricyclic antidepressant-like complications after cyclobenzaprine overdose.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Chi-Square Distributio | 2011 |
Differential effectiveness of tianeptine, clonidine and amitriptyline in blocking traumatic memory expression, anxiety and hypertension in an animal model of PTSD.
Topics: Adrenocorticotropic Hormone; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Antihypertens | 2013 |
CLINICAL USE OF AMITRIPTYLINE FOR THE TREATMENT OF PSYCHONEUROTIC REACTIVE ANXIETY AND DEPRESSION.
Topics: Amitriptyline; Anxiety; Arthritis, Rheumatoid; Asthma; Coronary Disease; Depression; Diabetes Mellit | 1964 |
METHYLDOPA AND AMITRIPTYLINE.
Topics: Amitriptyline; Depression; Depressive Disorder; Drug Synergism; Drug Therapy; Hypertension; Methyldo | 1965 |
Pregabalin-induced remission in a 62-year-old woman with a 20-year history of vulvodynia.
Topics: Amitriptyline; Analgesics; Anti-Ulcer Agents; Anticoagulants; Antidepressive Agents; Anxiety; Cardio | 2007 |
[Restraining action of antidepressive agents of the imipramine group on the cardiovascular centers].
Topics: Action Potentials; Amitriptyline; Amygdala; Animals; Antidepressive Agents; Blood Pressure; Carotid | 1967 |
Will amitriptyline prevent the "cheese" reaction of monoamine-oxidase inhibitors?
Topics: Adult; Amitriptyline; Blood Pressure; Cheese; Depression; Drug Synergism; Female; Humans; Hypertensi | 1982 |
Clonidine withdrawal complicated by amitriptyline therapy.
Topics: Aged; Amitriptyline; Anxiety; Clonidine; Female; Humans; Hypertension; Intraoperative Care; Methyldo | 1983 |
Treatment of disease without the use of drugs. V. Phasing out of benzodiazepine and amitriptyline medication with thought control.
Topics: Adult; Amitriptyline; Behavior Therapy; Benzodiazepines; Breathing Exercises; Female; Gastritis; Hum | 1980 |
Hypertension during coprescription of mirtazapine and low-dose amitriptyline.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Depressive Disorder; Drug Therapy, Combination; Hum | 1998 |
The effect of tricyclic antidepressants (TA) on the circulatory system in primary arterial hypertension.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Catecholamines; Hemodynamics; Humans; Hypertension; | 1979 |
[Clinical and statistical evaluation of the hypotensive effectiveness of 3 therapeutic plans in essential hypertension].
Topics: Adolescent; Adult; Amitriptyline; Antihypertensive Agents; Chlorthalidone; Diazepam; Drug Therapy, C | 1978 |
Hypertensive crisis in a patient given sinemet, metoclopramide, and amitriptyline.
Topics: Acute Disease; Amitriptyline; Carbidopa; Drug Combinations; Drug Therapy, Combination; Female; Human | 1977 |
Combining tricyclic and monoamine oxidase inhibitor antidepressants.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Depression; Drug Therapy, Combination; Humans; Hype | 1976 |
Influence of tricyclic antidepressant drugs on experimental arterial hypertension.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Corticosterone; Female; Hexobarbital; Hype | 1975 |
Antagonism of antihypertensive effect of guanfacine by tricyclic antidepressants.
Topics: Adult; Amitriptyline; Drug Interactions; Female; Guanfacine; Humans; Hypertension; Imipramine | 1991 |
Susceptibility to spontaneous MAOI hypertensive episodes.
Topics: Acute Disease; Adult; Amitriptyline; Depressive Disorder; Drug Interactions; Hospitalization; Humans | 1991 |
Case report of sudden and unexpected death after tricyclic overdose.
Topics: Adult; Amitriptyline; Death, Sudden; Diazepam; Female; Humans; Hypertension; Hypokalemia; Suicide, A | 1985 |
Central nervous actions and screening methods of antidepressants.
Topics: Acetylcholine; Amitriptyline; Animals; Antidepressive Agents; Behavior, Animal; Biogenic Amines; Blo | 1972 |
Myocardial infarction after exercise-induced electrocardiographic changes in a patient with variant angina pectoris.
Topics: Amitriptyline; Angina Pectoris; Arteriosclerosis; Catheterization; Diabetes Complications; Electroca | 1974 |
[True and false adverse effects of thymoanaleptic medications].
Topics: Amitriptyline; Antidepressive Agents; Chemical and Drug Induced Liver Injury; Cholestasis; Depressio | 1968 |
[Experimental study of direct vascular activity of amitriptyline].
Topics: Amitriptyline; Animals; Blood Vessels; Central Nervous System Stimulants; Ethanolamines; Heart; Hype | 1967 |
[Tranquillisers in the treatment of psychosomatic diseases].
Topics: Amitriptyline; Asthma; Benzazepines; Benzene Derivatives; Chlordiazepoxide; Colitis, Ulcerative; Dru | 1972 |
Letter: Concern over the categorization of depression in children.
Topics: Amitriptyline; Child; Depression; Female; Humans; Hypertension; Intelligence; Learning Disabilities; | 1974 |
Insidious and prolonged antagonism of guanethidine by amitriptyline.
Topics: Amitriptyline; Blood Pressure; Depression; Guanethidine; Humans; Hypertension; Male; Middle Aged | 1970 |
Tricyclic antidepressants and monoamine oxidase inhibitors.
Topics: Administration, Oral; Adolescent; Adult; Aged; Amitriptyline; Animals; Depression; Desipramine; Drug | 1971 |
[Psychodynamics and psychopahrmacological therapy of essential hypertension].
Topics: Amitriptyline; Chlordiazepoxide; Humans; Hypertension; Psychophysiologic Disorders | 1967 |
Psychopharmacological approach to psychosomatic medicine. Experimental and clinical research.
Topics: Amitriptyline; Amphetamine; Animals; Anxiety Disorders; Benactyzine; Depression; Guinea Pigs; Hostil | 1967 |
Circulatory lability and depression.
Topics: Aged; Amitriptyline; Blood Pressure Determination; Depression; Dysautonomia, Familial; Humans; Hyper | 1966 |