Page last updated: 2024-10-22

amitriptyline and Blood Poisoning

amitriptyline has been researched along with Blood Poisoning in 4 studies

Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.

Research Excerpts

ExcerptRelevanceReference
"The primary analysis quantified opioid overdose risk across 7 prescription opioid-skeletal muscle relaxant therapies and a negative control outcome (sepsis) to assess potential confounding by unmeasured illicit opioid use."1.72Comparative Risk of Opioid Overdose With Concomitant Use of Prescription Opioids and Skeletal Muscle Relaxants. ( Barnett, ML; Bykov, K; Gagne, JJ; Glynn, RJ; Khan, NF; Vine, SM, 2022)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Khan, NF1
Bykov, K1
Barnett, ML1
Glynn, RJ1
Vine, SM1
Gagne, JJ1
Xia, BT2
Beckmann, N3
Winer, LK2
Kim, Y1
Goetzman, HS1
Veile, RE1
Gulbins, E3
Goodman, MD1
Nomellini, V2
Caldwell, CC2
Pugh, AM1
Pritts, TA1
Peng, H1
Li, C1
Kadow, S1
Henry, BD1
Steinmann, J1
Becker, KA1
Riehle, A1
Wilker, B1
Li, PL1
Pritts, T1
Edwards, MJ1
Zhang, Y1
Grassmé, H1

Other Studies

4 other studies available for amitriptyline and Blood Poisoning

ArticleYear
Comparative Risk of Opioid Overdose With Concomitant Use of Prescription Opioids and Skeletal Muscle Relaxants.
    Neurology, 2022, 09-27, Volume: 99, Issue:13

    Topics: Amitriptyline; Analgesics, Opioid; Baclofen; Benzodiazepines; Carisoprodol; Chlorzoxazone; Cohort St

2022
Amitriptyline Treatment Mitigates Sepsis-Induced Tumor Necrosis Factor Expression and Coagulopathy.
    Shock (Augusta, Ga.), 2019, Volume: 51, Issue:3

    Topics: Amitriptyline; Animals; Blood Coagulation Disorders; Disease Models, Animal; Gene Expression Regulat

2019
Amitriptyline Reduces Inflammation and Mortality in a Murine Model of Sepsis.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2019, Volume: 52, Issue:3

    Topics: Amitriptyline; Animals; Bronchoalveolar Lavage Fluid; Ceramides; Chemokine CCL2; Cytokines; Disease

2019
Acid sphingomyelinase inhibition protects mice from lung edema and lethal Staphylococcus aureus sepsis.
    Journal of molecular medicine (Berlin, Germany), 2015, Volume: 93, Issue:6

    Topics: Amitriptyline; Animals; Anti-Bacterial Agents; Ceramides; Enzyme Inhibitors; Gene Knockout Technique

2015