amitriptyline has been researched along with Blood Poisoning in 4 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Excerpt | Relevance | Reference |
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"The primary analysis quantified opioid overdose risk across 7 prescription opioid-skeletal muscle relaxant therapies and a negative control outcome (sepsis) to assess potential confounding by unmeasured illicit opioid use." | 1.72 | Comparative Risk of Opioid Overdose With Concomitant Use of Prescription Opioids and Skeletal Muscle Relaxants. ( Barnett, ML; Bykov, K; Gagne, JJ; Glynn, RJ; Khan, NF; Vine, SM, 2022) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 3 (75.00) | 24.3611 |
2020's | 1 (25.00) | 2.80 |
Authors | Studies |
---|---|
Khan, NF | 1 |
Bykov, K | 1 |
Barnett, ML | 1 |
Glynn, RJ | 1 |
Vine, SM | 1 |
Gagne, JJ | 1 |
Xia, BT | 2 |
Beckmann, N | 3 |
Winer, LK | 2 |
Kim, Y | 1 |
Goetzman, HS | 1 |
Veile, RE | 1 |
Gulbins, E | 3 |
Goodman, MD | 1 |
Nomellini, V | 2 |
Caldwell, CC | 2 |
Pugh, AM | 1 |
Pritts, TA | 1 |
Peng, H | 1 |
Li, C | 1 |
Kadow, S | 1 |
Henry, BD | 1 |
Steinmann, J | 1 |
Becker, KA | 1 |
Riehle, A | 1 |
Wilker, B | 1 |
Li, PL | 1 |
Pritts, T | 1 |
Edwards, MJ | 1 |
Zhang, Y | 1 |
Grassmé, H | 1 |
4 other studies available for amitriptyline and Blood Poisoning
Article | Year |
---|---|
Comparative Risk of Opioid Overdose With Concomitant Use of Prescription Opioids and Skeletal Muscle Relaxants.
Topics: Amitriptyline; Analgesics, Opioid; Baclofen; Benzodiazepines; Carisoprodol; Chlorzoxazone; Cohort St | 2022 |
Amitriptyline Treatment Mitigates Sepsis-Induced Tumor Necrosis Factor Expression and Coagulopathy.
Topics: Amitriptyline; Animals; Blood Coagulation Disorders; Disease Models, Animal; Gene Expression Regulat | 2019 |
Amitriptyline Reduces Inflammation and Mortality in a Murine Model of Sepsis.
Topics: Amitriptyline; Animals; Bronchoalveolar Lavage Fluid; Ceramides; Chemokine CCL2; Cytokines; Disease | 2019 |
Acid sphingomyelinase inhibition protects mice from lung edema and lethal Staphylococcus aureus sepsis.
Topics: Amitriptyline; Animals; Anti-Bacterial Agents; Ceramides; Enzyme Inhibitors; Gene Knockout Technique | 2015 |