Page last updated: 2024-10-22

amitriptyline and Bladder Pain Syndrome

amitriptyline has been researched along with Bladder Pain Syndrome in 31 studies

Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.

Research Excerpts

ExcerptRelevanceReference
"Amitriptyline is frequently used to treat patients with interstitial cystitis/painful bladder syndrome."9.14Effect of amitriptyline on symptoms in treatment naïve patients with interstitial cystitis/painful bladder syndrome. ( Burks, DA; Cen, L; Chai, TC; FitzGerald, MP; Foster, HE; Hanno, PM; Kreder, KJ; Kusek, JW; Landis, JR; Lukacz, ES; Mayer, RD; Nickel, JC; Nyberg, LM; Payne, CK; Peters, KM; Propert, KJ; Yang, CC; Yang, W, 2010)
"We compared the effectiveness of intravesical combination treatment and intravesical treatment plus low-dose amitriptyline in patients with primary bladder pain syndrome (PBPS)."8.12The effect of intravesical cocktail therapy combined with low-dose amitriptyline on primary bladder pain syndrome. ( Abat, D; Altunkol, A; Gökalp, F, 2022)
"The European Society for the Study of Interstitial Cystitis (ESSIC) recommended that interstitial cystitis (IC) should be replaced by bladder pain syndrome (BPS), which focused more attention on the painful or discomfort feeling related to bladder and weakened the importance of cystoscopy in diagnosis process."5.40Effect of amitriptyline in treatment interstitial cystitis or bladder pain syndrome according to two criteria: does ESSIC criteria change the response rate? ( Ding, Q; Fang, Z; Sun, Y; Zheng, J, 2014)
"We are motivated by a randomized clinical trial evaluating the efficacy of amitriptyline for the treatment of interstitial cystitis and painful bladder syndrome in treatment-naïve patients."5.19Estimating the efficacy of an interstitial cystitis/painful bladder syndrome medication in a randomized trial with both non-adherence and loss to follow-up. ( Landis, JR; Propert, KJ; Yang, W, 2014)
"Amitriptyline is frequently used to treat patients with interstitial cystitis/painful bladder syndrome."5.14Effect of amitriptyline on symptoms in treatment naïve patients with interstitial cystitis/painful bladder syndrome. ( Burks, DA; Cen, L; Chai, TC; FitzGerald, MP; Foster, HE; Hanno, PM; Kreder, KJ; Kusek, JW; Landis, JR; Lukacz, ES; Mayer, RD; Nickel, JC; Nyberg, LM; Payne, CK; Peters, KM; Propert, KJ; Yang, CC; Yang, W, 2010)
"We compared the effectiveness of intravesical combination treatment and intravesical treatment plus low-dose amitriptyline in patients with primary bladder pain syndrome (PBPS)."4.12The effect of intravesical cocktail therapy combined with low-dose amitriptyline on primary bladder pain syndrome. ( Abat, D; Altunkol, A; Gökalp, F, 2022)
"The addition of ALA/n-3 PUFAs to amitriptyline treatment in patients with VBD/PBS appears to improve outcomes and may allow for a lower dosage of amitriptyline, which may lead to fewer adverse effects."2.84Alpha Lipoic Acid Plus Omega-3 Fatty Acids for Vestibulodynia Associated With Painful Bladder Syndrome. ( Felice, R; Gambini, D; Graziottin, A; Murina, F, 2017)
"Amitriptyline was taken strictly at bedtime following an established self-titration protocol without a limitation of the maximum daily dosage."2.75Long-term results of amitriptyline treatment for interstitial cystitis. ( Hertle, L; van Ophoven, A, 2010)
" Patients were prospectively treated for 4 months with a self-titration protocol that allowed them to escalate drug dosage in 25 mg increments in 1 week-intervals (maximum dosage 100 mg)."2.71A prospective, randomized, placebo controlled, double-blind study of amitriptyline for the treatment of interstitial cystitis. ( Heinecke, A; Hertle, L; Pokupic, S; van Ophoven, A, 2004)
"Amitriptyline was received strictly at bedtime following an established self-titration protocol without a limitation of the maximum daily dose."2.71Long-term results of amitriptyline treatment for interstitial cystitis. ( Hertle, L; van Ophoven, A, 2005)
"Interstitial cystitis (IC) and bladder pain syndrome (BPS) are chronic conditions that can be debilitating for patients."2.58An evaluation of the pharmacotherapy for interstitial cystitis. ( Giusto, LL; Shoskes, DA; Zahner, PM, 2018)
"The so-called interstitial cystitis is a chronic pain syndrome rather than a purely end organ disease of the urinary bladder."2.44[The complexity of chronic pelvic pain exemplified by the condition currently called interstitial cystitis. Part 2: Treatment]. ( Binder, I; Rossbach, G; van Ophoven, A, 2008)
"Painful bladder syndrome/interstitial cystitis (PBS/IC) is a controversial subject."2.44What's new in the diagnosis and management of painful bladder syndrome/interstitial cystitis? ( Seth, A; Teichman, JM, 2008)
"Interstitial cystitis is an enigmatic and frustrating condition to manage as a physician and to cope with as a patient."2.44Interstitial cystitis. ( Jones, A; Kelada, E, 2007)
"Symptoms of interstitial cystitis can usually be successfully managed with heparinoid therapy to theoretically alter bladder urothelial abnormalities, and with oral medications to inhibit neural upregulation or to control mast cell dysfunction."2.44Rational approaches to the treatment of patients with interstitial cystitis. ( Evans, RJ; Moldwin, RM; Rosenberg, MT; Stanford, EJ, 2007)
"Interstitial cystitis/painful bladder syndrome is a chronic disease characterized by pain, frequency, urgency, and nocturia and diagnosed primarily in women."2.44Interstitial cystitis/painful bladder syndrome. ( Warren, JW, 2007)
"Physicians should keep the diagnosis of interstitial cystitis in mind for all patients presenting with pelvic pain or urinary symptoms."2.43Interstitial cystitis: a primary care perspective. ( Page, S; Parsons, CL; Rosenberg, M, 2005)
"The adjusted hazard ratio (HR) for maculopathy in PPS users was 2."1.72Risk of maculopathy with pentosan polysulfate sodium use. ( Bae, SS; Etminan, M; Kezouh, A; Maberley, D; Sodhi, M, 2022)
"Amitriptyline was prescribed to 223 women with IC/BPS, only 125 of which (56%) had a documented history of depression."1.72Do medication prescription patterns follow guidelines in a cohort of women with interstitial cystitis/bladder pain syndrome? ( Anger, JT; Barbour, KE; Bresee, C; De Hoedt, AM; Freedland, SJ; Kim, J; Tholemeier, LN, 2022)
"Current management of bladder pain syndrome (BPS) was evaluated through a prospective electronic questionnaire posted on three patient support groups and sent to all members on the British Society of Urogynaecology (BSUG) database."1.43An assessment of clinicians' and patients' experiences in the management of bladder pain syndrome. ( Khan, KS; Tirlapur, SA, 2016)
"The European Society for the Study of Interstitial Cystitis (ESSIC) recommended that interstitial cystitis (IC) should be replaced by bladder pain syndrome (BPS), which focused more attention on the painful or discomfort feeling related to bladder and weakened the importance of cystoscopy in diagnosis process."1.40Effect of amitriptyline in treatment interstitial cystitis or bladder pain syndrome according to two criteria: does ESSIC criteria change the response rate? ( Ding, Q; Fang, Z; Sun, Y; Zheng, J, 2014)
"Bladder pain syndrome/interstitial cystitis (BPS/IC) is a chronic disease with a significant impact on quality of life."1.39Treatment costs of bladder pain syndrome/interstitial cystitis in Austria: a pharmacoeconomic approach following current guidelines. ( Engelhardt, P; Riedl, C; Schwarz, B, 2013)
"We report a case of a patient with interstitial cystitis."1.36[Interstitial cystitis. A challenge for the clinician]. ( Bruetman, JE; Comercio, LP; Finn, BC; González, M; Quezel, M; Young, P, 2010)
"Interstitial cystitis is associated with substantial costs and health care resource utilization."1.35Treatment modalities, health care resource utilization, and costs in patients diagnosed with interstitial cystitis. ( Chen, A; Lunacsek, OE; Sand, PK; Stanford, EJ; Wan, GJ, 2008)
"Interstitial cystitis is a particular type of cystitis with clear urine, essentially observed in women."1.30[Interstitial cystitis]. ( Lépinard, V, 1998)
"Definitive diagnosis of interstitial cystitis requires cystoscopy and hydrodistention."1.30Irritative voiding symptoms: identifying the cause. ( Gormley, EA, 1999)

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (6.45)18.2507
2000's13 (41.94)29.6817
2010's12 (38.71)24.3611
2020's4 (12.90)2.80

Authors

AuthorsStudies
Abat, D1
Altunkol, A1
Gökalp, F1
Bae, SS1
Sodhi, M1
Maberley, D1
Kezouh, A1
Etminan, M1
Tholemeier, LN1
Bresee, C1
De Hoedt, AM1
Barbour, KE1
Kim, J1
Freedland, SJ1
Anger, JT2
Şahin, MF1
Özcan, R1
Malak, A1
Doğan, Ç1
Yazıcı, CM1
Özcan, M1
Akgül, M1
Murina, F1
Graziottin, A1
Felice, R1
Gambini, D1
Giusto, LL1
Zahner, PM1
Shoskes, DA1
Sun, Y1
Fang, Z1
Ding, Q1
Zheng, J1
Riedl, C1
Engelhardt, P1
Schwarz, B1
Kapelner, A1
Krieger, A1
Dancel, R1
Mounsey, A1
Handler, L1
Tirlapur, SA1
Khan, KS1
Stanford, EJ2
Chen, A1
Wan, GJ1
Lunacsek, OE1
Sand, PK1
Binder, I1
Rossbach, G1
van Ophoven, A4
Seth, A1
Teichman, JM2
Sea, J1
Hertle, L3
Foster, HE1
Hanno, PM1
Nickel, JC1
Payne, CK2
Mayer, RD1
Burks, DA1
Yang, CC1
Chai, TC1
Kreder, KJ1
Peters, KM1
Lukacz, ES1
FitzGerald, MP1
Cen, L1
Landis, JR3
Propert, KJ3
Yang, W2
Kusek, JW2
Nyberg, LM2
Young, P1
Finn, BC1
González, M1
Comercio, LP1
Quezel, M1
Bruetman, JE1
Zabihi, N1
Clemens, JQ1
Saigal, CS1
Rodriguez, LV1
Pokupic, S1
Heinecke, A1
Rosenberg, M1
Parsons, CL1
Page, S1
Kelada, E1
Jones, A1
Moldwin, RM2
Evans, RJ1
Rosenberg, MT1
Warren, JW1
Lépinard, V1
Gormley, EA1
Rovner, E1
Brensinger, C1
Wein, AJ1
Foy, M1
Kirkemo, A1
Sievert, KD1
Edenfeld, KD1
Oberpenning, F1
Piechota, HJ1
Sant, GR1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
IC PaIN Trial: Interstitial Cystitis Pain Improvement With Naltrexone, the Effect of Low Dose Naltrexone on Symptoms and Pain of Patients With Interstitial Cystitis/Painful Bladder Syndrome a Randomized Placebo-controlled Prospective Trial[NCT04313972]Phase 42 participants (Actual)Interventional2021-09-07Completed
A Randomized Multicenter Clinical Trial to Evaluate the Efficacy of Amitriptyline for the Treatment of Painful Bladder Syndrome (PBS) in Newly Diagnosed Patients[NCT00124306]Phase 3271 participants (Actual)Interventional2005-02-28Completed
A Randomized Trial of Bladder Instillations Versus Onabotulinumtoxin A for Treatment of Interstitial Cystitis/Bladder Pain Syndrome[NCT04401176]Phase 258 participants (Actual)Interventional2020-09-15Completed
Use of Preemptive Pudendal Nerve Block Prior to Hydrodistension for the Treatment of Interstitial Cystitis/Painful Bladder Syndrome (IC/PBS): a Prospective, Double-blinded, Randomized Control Trial[NCT02517996]18 participants (Actual)Interventional2015-02-28Terminated (stopped due to Preliminary results were promising when interim analysis performed but terminated due to primary investigators left recruitment site.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change in IC Symptom Index Questionnaire With Preemptive Pudendal Nerve Block Compared to Saline

"To determine the change in interstitial cystitis symptom index at baseline, 2 hours, 2 weeks, 6 weeks and 3 months after hydrodistention with preemptive pudendal nerve block (1% Lidocaine) compared to hydrodistention with placebo (saline).~The IC symptom index questionnaire consists of 4 questions on IC symptoms. 2 of the questions have 6 answer choices ranging from 0-never, to 5-almost always. 1 question has 6 answer choices ranging from 0-never to 5-usually. 1 question has 7 answer choices ranging from 0-never to 6-5 or more times. The numerical score for each question are added together, with a minimum score of 0 and a maximum score of 21. A higher score indicates greater severity of IC symptoms." (NCT02517996)
Timeframe: Baseline, 2 weeks, 6 weeks, 3 months (Up to 3 months)

,
Interventionscore on a scale (Mean)
Baseline2 weeks6 weeks12 weeks
1% Lidocaine12.511.4311.810
Normal Saline1098.675

Change in Pain Level as Assessed by the Visual Analog Scale (VAS)

"To determine the change in pain at 2 hours, 2 weeks, 6 weeks, and 3 months postoperatively in patients undergoing hydrodistention with preemptive pudendal nerve block (1% Lidocaine) compared to hydrodistention with placebo (saline) using the visual analog scale (VAS).~VAS consists of a 10cm horizontal line with the minimum endpoint labeled no pain (0) and maximum labeled worst pain ever (10). Patients placed a mark on the point that corresponds to the level of pain severity they felt. The cm distance from the low end of the VAS to the patient's mark is used as the numerical index of the intensity of pain. Pain scores of 3.0-5.4 cm are moderate, over 5.4 indicates severe pain." (NCT02517996)
Timeframe: Baseline, 2 hours, 2 weeks, 6 weeks, 3 months (Up to 3 months)

,
Interventionscore on a scale (Mean)
Pre operative VAS scorePost operative VAS score2 week post operative VAS scores6 week post operative VAS score12 weeks post operative VAS score
1% Lidocaine3.1253.752.732.6
Normal Saline4.554.84.332

Change in Pelvic Urgency, Pain, and Frequency (PUF) Questionnaire With Preemptive Pudendal Nerve Block Compared to Saline

"To determine the change in pelvic urgency, pain and frequency (PUF) questionnaire at baseline, 2 hours, 2 weeks, 6 weeks and 3 months after hydrodistention with preemptive pudendal nerve block (1% Lidocaine) compared to hydrodistention with placebo (saline).~The Pelvic Urgency, Pain, and Frequency Patient Symptom Scale asks 11 questions, 7 on PUF symptoms, 4 on how bothersome PUF symptoms are. Symptom questions include 3, 4, or 5 ranked answers, with higher answers indicating more voids, or greater frequency of pain. The bother questions each of 4 ranked answers from 0-never, to 3-always. The symptom score is added, the bother score is added, and then the total score is added. The total PUF score is then reported. The minimum score is 0 and the maximum score is 35, and a higher score indicates greater symptoms and higher bother from pelvic pain and frequency." (NCT02517996)
Timeframe: Baseline, 2 hours, 2 weeks, 6 weeks, 3 months (Up to 3 months)

,
Interventionscore on a scale (Mean)
Baseline2 weeks6 weeks12 weeks
1% Lidocaine22.6318.8318.217.2
Normal Saline1917.416.714

Change in Problem Index (O'Leary Sant) With Preemptive Pudendal Nerve Block Compared to Saline

"To determine the change in problem index (O'Leary Sant) at baseline, 2 hours, 2 weeks, 6 weeks and 3 months after hydrodistention with preemptive pudendal nerve block (1% Lidocaine) compared to hydrodistention with placebo (saline).~The IC problem index questionnaire consists of 4 questions on how much of a problem a patient's IC symptoms cause them. Each question has 5 answer choices ranging from 0-no problem, to 4-big problem. The numerical score for each question are added together, with a minimum score of 0 and a maximum score of 16. A higher score indicates that IC symptoms cause more problems for the patient." (NCT02517996)
Timeframe: Baseline, 2 hours, 2 weeks, 6 weeks, 3 months (Up to 3 months)

,
Interventionscore on a scale (Mean)
Baseline2 weeks6 weeks12 weeks
1% Lidocaine11.759.71109.6
Normal Saline9.438.67.336

Reviews

10 reviews available for amitriptyline and Bladder Pain Syndrome

ArticleYear
An evaluation of the pharmacotherapy for interstitial cystitis.
    Expert opinion on pharmacotherapy, 2018, Volume: 19, Issue:10

    Topics: Amitriptyline; Antibodies, Monoclonal; Antidepressive Agents, Tricyclic; Cimetidine; Cystitis, Inter

2018
[The complexity of chronic pelvic pain exemplified by the condition currently called interstitial cystitis. Part 2: Treatment].
    Aktuelle Urologie, 2008, Volume: 39, Issue:4

    Topics: Administration, Intravesical; Administration, Oral; Amitriptyline; Arginine; Botulinum Toxins, Type

2008
What's new in the diagnosis and management of painful bladder syndrome/interstitial cystitis?
    Current urology reports, 2008, Volume: 9, Issue:5

    Topics: Amitriptyline; Analgesics, Non-Narcotic; Cystitis, Interstitial; Cystoscopy; Glycoproteins; Humans;

2008
Paediatric painful bladder syndrome/interstitial cystitis: diagnosis and treatment.
    Drugs, 2009, Volume: 69, Issue:3

    Topics: Administration, Intravesical; Amitriptyline; Child; Cimetidine; Cystitis, Interstitial; Diet Therapy

2009
Interstitial cystitis: a primary care perspective.
    Cleveland Clinic journal of medicine, 2005, Volume: 72, Issue:8

    Topics: Amitriptyline; Cystitis, Interstitial; Disease Progression; Humans; Hydroxyzine; Primary Health Care

2005
Interstitial cystitis.
    Archives of gynecology and obstetrics, 2007, Volume: 275, Issue:4

    Topics: Amitriptyline; Analgesics; Anti-Bacterial Agents; BCG Vaccine; Behavior Therapy; Cyclosporine; Cysti

2007
Rational approaches to the treatment of patients with interstitial cystitis.
    Urology, 2007, Volume: 69, Issue:4 Suppl

    Topics: Administration, Intravesical; Administration, Oral; Amitriptyline; Anesthetics, Local; Combined Moda

2007
Interstitial cystitis/painful bladder syndrome.
    Urologic nursing, 2007, Volume: 27, Issue:3

    Topics: Amitriptyline; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; C

2007
[Oral therapy of interstitial cystitis].
    Der Urologe. Ausg. A, 2000, Volume: 39, Issue:6

    Topics: Administration, Oral; Amitriptyline; Analgesics; Anti-Inflammatory Agents; Cystitis, Interstitial; H

2000
Interstitial cystitis: a pathophysiology and treatment update.
    Clinical obstetrics and gynecology, 2002, Volume: 45, Issue:1

    Topics: Administration, Intravesical; Amitriptyline; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive

2002

Trials

6 trials available for amitriptyline and Bladder Pain Syndrome

ArticleYear
Alpha Lipoic Acid Plus Omega-3 Fatty Acids for Vestibulodynia Associated With Painful Bladder Syndrome.
    Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC, 2017, Volume: 39, Issue:3

    Topics: Adolescent; Adult; Amitriptyline; Analgesics, Non-Narcotic; Antioxidants; Cystitis, Interstitial; Do

2017
Long-term results of amitriptyline treatment for interstitial cystitis.
    Aktuelle Urologie, 2010, Volume: 41 Suppl 1

    Topics: Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Antineoplastic Combined Chemotherapy P

2010
Effect of amitriptyline on symptoms in treatment naïve patients with interstitial cystitis/painful bladder syndrome.
    The Journal of urology, 2010, Volume: 183, Issue:5

    Topics: Adult; Amitriptyline; Analgesics, Non-Narcotic; Cystitis, Interstitial; Double-Blind Method; Female;

2010
Effect of amitriptyline on symptoms in treatment naïve patients with interstitial cystitis/painful bladder syndrome.
    The Journal of urology, 2010, Volume: 183, Issue:5

    Topics: Adult; Amitriptyline; Analgesics, Non-Narcotic; Cystitis, Interstitial; Double-Blind Method; Female;

2010
Effect of amitriptyline on symptoms in treatment naïve patients with interstitial cystitis/painful bladder syndrome.
    The Journal of urology, 2010, Volume: 183, Issue:5

    Topics: Adult; Amitriptyline; Analgesics, Non-Narcotic; Cystitis, Interstitial; Double-Blind Method; Female;

2010
Effect of amitriptyline on symptoms in treatment naïve patients with interstitial cystitis/painful bladder syndrome.
    The Journal of urology, 2010, Volume: 183, Issue:5

    Topics: Adult; Amitriptyline; Analgesics, Non-Narcotic; Cystitis, Interstitial; Double-Blind Method; Female;

2010
Effect of amitriptyline on symptoms in treatment naïve patients with interstitial cystitis/painful bladder syndrome.
    The Journal of urology, 2010, Volume: 183, Issue:5

    Topics: Adult; Amitriptyline; Analgesics, Non-Narcotic; Cystitis, Interstitial; Double-Blind Method; Female;

2010
Effect of amitriptyline on symptoms in treatment naïve patients with interstitial cystitis/painful bladder syndrome.
    The Journal of urology, 2010, Volume: 183, Issue:5

    Topics: Adult; Amitriptyline; Analgesics, Non-Narcotic; Cystitis, Interstitial; Double-Blind Method; Female;

2010
Effect of amitriptyline on symptoms in treatment naïve patients with interstitial cystitis/painful bladder syndrome.
    The Journal of urology, 2010, Volume: 183, Issue:5

    Topics: Adult; Amitriptyline; Analgesics, Non-Narcotic; Cystitis, Interstitial; Double-Blind Method; Female;

2010
Effect of amitriptyline on symptoms in treatment naïve patients with interstitial cystitis/painful bladder syndrome.
    The Journal of urology, 2010, Volume: 183, Issue:5

    Topics: Adult; Amitriptyline; Analgesics, Non-Narcotic; Cystitis, Interstitial; Double-Blind Method; Female;

2010
Effect of amitriptyline on symptoms in treatment naïve patients with interstitial cystitis/painful bladder syndrome.
    The Journal of urology, 2010, Volume: 183, Issue:5

    Topics: Adult; Amitriptyline; Analgesics, Non-Narcotic; Cystitis, Interstitial; Double-Blind Method; Female;

2010
Estimating the efficacy of an interstitial cystitis/painful bladder syndrome medication in a randomized trial with both non-adherence and loss to follow-up.
    Statistics in medicine, 2014, Sep-10, Volume: 33, Issue:20

    Topics: Amitriptyline; Analgesics, Non-Narcotic; Computer Simulation; Cystitis, Interstitial; Humans; Logist

2014
A prospective, randomized, placebo controlled, double-blind study of amitriptyline for the treatment of interstitial cystitis.
    The Journal of urology, 2004, Volume: 172, Issue:2

    Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Cystitis, Interstitial; Double-Blind Method;

2004
Long-term results of amitriptyline treatment for interstitial cystitis.
    The Journal of urology, 2005, Volume: 174, Issue:5

    Topics: Administration, Oral; Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Cystitis, Inters

2005

Other Studies

15 other studies available for amitriptyline and Bladder Pain Syndrome

ArticleYear
The effect of intravesical cocktail therapy combined with low-dose amitriptyline on primary bladder pain syndrome.
    International urogynecology journal, 2022, Volume: 33, Issue:5

    Topics: Administration, Intravesical; Amitriptyline; Cystitis, Interstitial; Humans; Nocturia; Surveys and Q

2022
Risk of maculopathy with pentosan polysulfate sodium use.
    British journal of clinical pharmacology, 2022, Volume: 88, Issue:7

    Topics: Amitriptyline; Cystitis, Interstitial; Humans; Macular Degeneration; Pentosan Sulfuric Polyester; Re

2022
Do medication prescription patterns follow guidelines in a cohort of women with interstitial cystitis/bladder pain syndrome?
    Neurourology and urodynamics, 2022, Volume: 41, Issue:5

    Topics: Amitriptyline; Chronic Pain; Cystitis, Interstitial; Drug Prescriptions; Female; Humans; Hydroxyzine

2022
The effect of the pandemic period on Bladder Pain Syndrome patients under amitriptyline treatment.
    Neurourology and urodynamics, 2023, Volume: 42, Issue:6

    Topics: Amitriptyline; COVID-19; Cystitis, Interstitial; Female; Humans; Male; Pandemics; Urinary Bladder, O

2023
Effect of amitriptyline in treatment interstitial cystitis or bladder pain syndrome according to two criteria: does ESSIC criteria change the response rate?
    Neurourology and urodynamics, 2014, Volume: 33, Issue:3

    Topics: Amitriptyline; Analgesics, Non-Narcotic; Cystitis, Interstitial; Cystoscopy; Female; Humans; Male; M

2014
Treatment costs of bladder pain syndrome/interstitial cystitis in Austria: a pharmacoeconomic approach following current guidelines.
    Clinical drug investigation, 2013, Volume: 33, Issue:10

    Topics: Amitriptyline; Austria; Cystitis, Interstitial; Economics, Pharmaceutical; Health Care Costs; Humans

2013
Matching on-the-fly: sequential allocation with higher power and efficiency.
    Biometrics, 2014, Volume: 70, Issue:2

    Topics: Algorithms; Amitriptyline; Biometry; Computer Simulation; Cystitis, Interstitial; Humans; Linear Mod

2014
Medications for treatment of interstitial cystitis.
    American family physician, 2015, Jan-15, Volume: 91, Issue:2

    Topics: Adult; Amitriptyline; Cimetidine; Cystitis, Interstitial; Evidence-Based Medicine; Female; Humans; H

2015
An assessment of clinicians' and patients' experiences in the management of bladder pain syndrome.
    Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 2016, Volume: 36, Issue:2

    Topics: Amitriptyline; Analgesics, Non-Narcotic; Anti-Bacterial Agents; Cystitis, Interstitial; Cystoscopy;

2016
Treatment modalities, health care resource utilization, and costs in patients diagnosed with interstitial cystitis.
    American journal of obstetrics and gynecology, 2008, Volume: 199, Issue:1

    Topics: Adult; Amitriptyline; Analgesics, Non-Narcotic; Cystitis, Interstitial; Cystoscopy; Delivery of Heal

2008
[Interstitial cystitis. A challenge for the clinician].
    Medicina, 2010, Volume: 70, Issue:4

    Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Cystitis, Interstitial; Female; Humans

2010
Treatment choice, duration, and cost in patients with interstitial cystitis and painful bladder syndrome.
    International urogynecology journal, 2011, Volume: 22, Issue:4

    Topics: Administration, Intravesical; Administration, Oral; Adrenergic Uptake Inhibitors; Adult; Aged; Amine

2011
[Interstitial cystitis].
    Annales d'urologie, 1998, Volume: 32, Issue:6-7

    Topics: Administration, Topical; Amitriptyline; Anti-Inflammatory Agents; Anticoagulants; Antidepressive Age

1998
Irritative voiding symptoms: identifying the cause.
    Hospital practice (1995), 1999, Dec-15, Volume: 34, Issue:13

    Topics: Adult; Amitriptyline; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cystitis, I

1999
Treatments used in women with interstitial cystitis: the interstitial cystitis data base (ICDB) study experience. The Interstitial Cystitis Data Base Study Group.
    Urology, 2000, Dec-20, Volume: 56, Issue:6

    Topics: Amitriptyline; Cohort Studies; Cystitis, Interstitial; Cystoscopy; Dilatation; Female; Food, Formula

2000