amitriptyline has been researched along with Black Fever in 2 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cyclobenzaprine (CBP) is a tricyclic structurally related to the antidepressant amitriptyline, differing only by the presence of a double bond in the central ring." | 1.46 | Cyclobenzaprine Raises ROS Levels in Leishmania infantum and Reduces Parasite Burden in Infected Mice. ( Abengózar, MA; Almeida-Amaral, EE; Andrade-Neto, VV; Barbas, C; Cunha-Júnior, EF; da Costa-Silva, TA; Galisteo Junior, AJ; Lima, ML; Rivas, L; Tempone, AG; Torres-Santos, EC, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lima, ML | 2 |
| Abengózar, MA | 2 |
| Torres-Santos, EC | 2 |
| Borborema, SET | 1 |
| Godzien, J | 1 |
| López-Gonzálvez, Á | 1 |
| Barbas, C | 2 |
| Rivas, L | 2 |
| Tempone, AG | 2 |
| Cunha-Júnior, EF | 1 |
| Andrade-Neto, VV | 1 |
| da Costa-Silva, TA | 1 |
| Galisteo Junior, AJ | 1 |
| Almeida-Amaral, EE | 1 |
2 other studies available for amitriptyline and Black Fever
| Article | Year |
|---|---|
Energy metabolism as a target for cyclobenzaprine: A drug candidate against Visceral Leishmaniasis.
Topics: Adenosine Triphosphate; Amitriptyline; Animals; Antiprotozoal Agents; Energy Metabolism; Humans; Lei | 2022 |
Cyclobenzaprine Raises ROS Levels in Leishmania infantum and Reduces Parasite Burden in Infected Mice.
Topics: Amitriptyline; Animals; Antiprotozoal Agents; Humans; Interferon-gamma; Interleukin-10; Interleukin- | 2017 |