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amitriptyline and Benign Neoplasms, Brain

amitriptyline has been researched along with Benign Neoplasms, Brain in 6 studies

Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.

Research Excerpts

ExcerptRelevanceReference
"In the present study, we investigated the effects of chronic in vitro administration of amitriptyline, a tricyclic antidepressant, on cyclic GMP formation stimulated by 5-hydroxytryptamine (5-HT) in the neuroblastoma x glioma hybrid cell line, NG 108-15, 5-HT (0."3.69Chronic amitriptyline exposure reduces 5-HT3 receptor-mediated cyclic GMP formation in NG 108-15 cells. ( Nishida, A; Shimizu, M; Yamawaki, S; Zensho, H, 1996)
"In this investigation the effects of tricyclic drugs on cellular respiration were studied using the anaplastic astrocytoma cell line IPSB-18 by use of a Clark-type oxygen electrode which measured changes in cellular respiration rate (oxygen consumption), in a dose-response assay."1.36The in vitro effects of tricyclic drugs and dexamethasone on cellular respiration of malignant glioma. ( Higgins, SC; Pilkington, GJ, 2010)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19902 (33.33)18.7374
1990's2 (33.33)18.2507
2000's1 (16.67)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Higgins, SC1
Pilkington, GJ1
Koval'chuk, VV1
Khouzam, HR1
Emery, PE1
Reaves, B1
Shimizu, M1
Nishida, A1
Zensho, H1
Yamawaki, S1
Glötzner, FL1
Samland, O1
Dommasch, D1
Blinder, MG1

Trials

1 trial available for amitriptyline and Benign Neoplasms, Brain

ArticleYear
[Pharmacologic correction of psycho-emotive disorders in the rehabilitation of patients after removal of brain tumors].
    Voprosy onkologii, 2007, Volume: 53, Issue:6

    Topics: Adult; Alprazolam; Amitriptyline; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Brain Neoplas

2007

Other Studies

5 other studies available for amitriptyline and Benign Neoplasms, Brain

ArticleYear
The in vitro effects of tricyclic drugs and dexamethasone on cellular respiration of malignant glioma.
    Anticancer research, 2010, Volume: 30, Issue:2

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Antineoplastic Agents, Hormonal; Antineoplastic Com

2010
Secondary mania in late life.
    Journal of the American Geriatrics Society, 1994, Volume: 42, Issue:1

    Topics: Age Factors; Aged; Amitriptyline; Bipolar Disorder; Brain Neoplasms; Diagnosis, Differential; Female

1994
Chronic amitriptyline exposure reduces 5-HT3 receptor-mediated cyclic GMP formation in NG 108-15 cells.
    Brain research, 1996, Nov-25, Volume: 741, Issue:1-2

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Benzamides; Bradykinin; Brain Neoplasms; Bridged Bi

1996
[Brain stem seizures with circumscrbed elementary symptoms].
    Der Nervenarzt, 1976, Volume: 47, Issue:9

    Topics: Adult; Amitriptyline; Ataxia; Brain Neoplasms; Brain Stem; Carbamazepine; Epilepsy; Female; Humans;

1976
Classification and treatment of depression.
    International psychiatry clinics, 1969, Volume: 6, Issue:2

    Topics: Adjustment Disorders; Amitriptyline; Anxiety; Bipolar Disorder; Brain Neoplasms; Depression; Histrio

1969