amitriptyline has been researched along with Becker Muscular Dystrophy in 1 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Therefore, the study objectives were to investigate the effects of the tricyclic antidepressant amitriptyline on mood, learning, central cytokine expression and skeletal muscle inflammation in mdx mice." | 7.80 | Amitriptyline is efficacious in ameliorating muscle inflammation and depressive symptoms in the mdx mouse model of Duchenne muscular dystrophy. ( Bouma, J; Jensen, L; Kulbida, R; Manning, J; O'Malley, D; Rai, P; Singh, SP; Yilmazer-Hanke, D, 2014) |
| " Therefore, the study objectives were to investigate the effects of the tricyclic antidepressant amitriptyline on mood, learning, central cytokine expression and skeletal muscle inflammation in mdx mice." | 3.80 | Amitriptyline is efficacious in ameliorating muscle inflammation and depressive symptoms in the mdx mouse model of Duchenne muscular dystrophy. ( Bouma, J; Jensen, L; Kulbida, R; Manning, J; O'Malley, D; Rai, P; Singh, SP; Yilmazer-Hanke, D, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Manning, J | 1 |
| Kulbida, R | 1 |
| Rai, P | 1 |
| Jensen, L | 1 |
| Bouma, J | 1 |
| Singh, SP | 1 |
| O'Malley, D | 1 |
| Yilmazer-Hanke, D | 1 |
1 other study available for amitriptyline and Becker Muscular Dystrophy
| Article | Year |
|---|---|
Amitriptyline is efficacious in ameliorating muscle inflammation and depressive symptoms in the mdx mouse model of Duchenne muscular dystrophy.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Depression; Disease Mode | 2014 |