amitriptyline has been researched along with Autosomal Dominant Juvenile Parkinson Disease in 5 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pretreatment of rotenone groups with AMI or IMI prevented rotenone-induced neuronal degeneration and increased striatal dopamine level with motor recovery." | 1.43 | Imipramine and amitriptyline ameliorate the rotenone model of Parkinson's disease in rats. ( Abdelkader, NF; El-Sayeh, BM; Kandil, EA; Saleh, S, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kamińska, K | 1 |
| Lenda, T | 1 |
| Konieczny, J | 1 |
| Wardas, J | 1 |
| Lorenc-Koci, E | 1 |
| Paumier, KL | 1 |
| Sortwell, CE | 1 |
| Madhavan, L | 1 |
| Terpstra, B | 1 |
| Celano, SL | 1 |
| Green, JJ | 1 |
| Imus, NM | 1 |
| Marckini, N | 1 |
| Daley, B | 1 |
| Steece-Collier, K | 1 |
| Collier, TJ | 1 |
| Kandil, EA | 1 |
| Abdelkader, NF | 1 |
| El-Sayeh, BM | 1 |
| Saleh, S | 1 |
| GILLINGHAM, FJ | 2 |
| KALYANARAMAN, S | 1 |
| SMYTHIES, JR | 1 |
5 other studies available for amitriptyline and Autosomal Dominant Juvenile Parkinson Disease
| Article | Year |
|---|---|
Interactions of the tricyclic antidepressant drug amitriptyline with L-DOPA in the striatum and substantia nigra of unilaterally 6-OHDA-lesioned rats. Relevance to motor dysfunction in Parkinson's disease.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Corpus Striatum; Drug Interactions; Levodo | 2018 |
Chronic amitriptyline treatment attenuates nigrostriatal degeneration and significantly alters trophic support in a rat model of parkinsonism.
Topics: Adrenergic Agents; Amitriptyline; Analgesics, Non-Narcotic; Animals; Brain-Derived Neurotrophic Fact | 2015 |
Imipramine and amitriptyline ameliorate the rotenone model of Parkinson's disease in rats.
Topics: Amitriptyline; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Antiparkinson Agents; | 2016 |
PARKINSON'S DISEASE.
Topics: Amitriptyline; Dextroamphetamine; Humans; Imipramine; Muscle Relaxants, Central; Neurosurgery; Orphe | 1963 |
A CASE OF POSTENCEPHALITIC PARKINSONISM RESPONDING TO COMBINED SURGICAL AND MEDICINAL TREATMENT.
Topics: Amitriptyline; Chlordiazepoxide; Depression; Depressive Disorder; Drug Therapy; Encephalitis; Eye Mo | 1965 |