amitriptyline has been researched along with Autism in 5 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The absence of neonatal seizures is a robust and important clinical differentiator between KCNQ2 gain-of-function and loss-of-function variants." | 1.72 | KCNQ2 R144 variants cause neurodevelopmental disability with language impairment and autistic features without neonatal seizures through a gain-of-function mechanism. ( Ambrosino, P; Amin, H; Bayat, A; Brilstra, E; Carotenuto, L; Cooper, EC; de Bellescize, J; Devinsky, O; Edery, P; Emrick, L; Goizet, C; Hong, W; Kleefstra, T; Kluger, G; Korenke, GC; Lee, HK; Lesca, G; Mefford, HC; Miceli, F; Michaud, V; Milh, M; Millevert, C; Mosca, I; Møller, RS; Risen, S; Riviello, J; Sands, T; Schrader, D; Soldovieri, MV; Taglialatela, M; Van-Gils, J; Ville, D; Weckhuysen, S; Willemsen, MH, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Miceli, F | 1 |
| Millevert, C | 1 |
| Soldovieri, MV | 1 |
| Mosca, I | 1 |
| Ambrosino, P | 1 |
| Carotenuto, L | 1 |
| Schrader, D | 1 |
| Lee, HK | 1 |
| Riviello, J | 1 |
| Hong, W | 1 |
| Risen, S | 1 |
| Emrick, L | 1 |
| Amin, H | 1 |
| Ville, D | 1 |
| Edery, P | 1 |
| de Bellescize, J | 1 |
| Michaud, V | 1 |
| Van-Gils, J | 1 |
| Goizet, C | 1 |
| Willemsen, MH | 1 |
| Kleefstra, T | 1 |
| Møller, RS | 1 |
| Bayat, A | 1 |
| Devinsky, O | 1 |
| Sands, T | 1 |
| Korenke, GC | 1 |
| Kluger, G | 1 |
| Mefford, HC | 1 |
| Brilstra, E | 1 |
| Lesca, G | 1 |
| Milh, M | 1 |
| Cooper, EC | 1 |
| Taglialatela, M | 1 |
| Weckhuysen, S | 1 |
| Pollard, AJ | 1 |
| Prendergast, M | 1 |
| Kehrer, HE | 1 |
| Ginestet, D | 1 |
| Peters, UH | 1 |
| Glück, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effectivity of Incentive Spirometry on Postoperative Pulmonary Complication After Major Abdominal Surgery In Indonesia Three Major Tertiary Hospitals: A Randomized Controlled Trial[NCT05795608] | 46 participants (Actual) | Interventional | 2015-07-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for amitriptyline and Autism
| Article | Year |
|---|---|
[Infantile autism and drug therapy].
Topics: Adolescent; Amitriptyline; Autistic Disorder; Child; Child, Preschool; Clinical Trials as Topic; Clo | 1978 |
4 other studies available for amitriptyline and Autism
| Article | Year |
|---|---|
KCNQ2 R144 variants cause neurodevelopmental disability with language impairment and autistic features without neonatal seizures through a gain-of-function mechanism.
Topics: Amitriptyline; Autistic Disorder; Epilepsy; Gain of Function Mutation; Humans; Infant, Newborn; Infa | 2022 |
Depressive pseudodementia in a child with autism.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Autistic Disorder; Child; Dementia; Depressive Diso | 2004 |
The psychiatrist attitudes and therapeutic means when faced with resistant depressions.
Topics: Amitriptyline; Amphetamine; Antidepressive Agents; Autistic Disorder; Depression; Drug Resistance; D | 1974 |
[Personality at the end of a depressive phase. Observations after cessation of the endogenous depressive phases].
Topics: Amitriptyline; Autistic Disorder; Bipolar Disorder; Defense Mechanisms; Female; Humans; Hypochondria | 1973 |