Page last updated: 2024-10-22

amitriptyline and Aura

amitriptyline has been researched along with Aura in 36 studies

Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.

Research Excerpts

ExcerptRelevanceReference
"Forty-two patients with depression and epilepsy were entered into an antidepressant trial of amitriptyline, nomifensine and placebo."5.05The treatment of depression in patients with epilepsy. A double-blind trial. ( Robertson, MM; Trimble, MR, 1985)
"Pregabalin (PGB) is used in drug-resistant epilepsy."4.31The investigation of antidepressant and anxiolytic effects of pregabalin and its mechanisms of action in rats. ( Aydın, Ş; Çivgin, ME; Dinçer Öner, S; Kılıç Tatlıcı, C; Kılıç, FS; Yazıcı, ZG; Yıldırım, C, 2023)
"He discusses treatment of headache in relation to management of the acute attack, avoidance of trigger factors, and pharmacological and nonpharmacological prophylaxis."2.37An overview of the classification, causes, and treatment of headache. ( Ziegler, DK, 1984)
"The absence of neonatal seizures is a robust and important clinical differentiator between KCNQ2 gain-of-function and loss-of-function variants."1.72KCNQ2 R144 variants cause neurodevelopmental disability with language impairment and autistic features without neonatal seizures through a gain-of-function mechanism. ( Ambrosino, P; Amin, H; Bayat, A; Brilstra, E; Carotenuto, L; Cooper, EC; de Bellescize, J; Devinsky, O; Edery, P; Emrick, L; Goizet, C; Hong, W; Kleefstra, T; Kluger, G; Korenke, GC; Lee, HK; Lesca, G; Mefford, HC; Miceli, F; Michaud, V; Milh, M; Millevert, C; Mosca, I; Møller, RS; Risen, S; Riviello, J; Sands, T; Schrader, D; Soldovieri, MV; Taglialatela, M; Van-Gils, J; Ville, D; Weckhuysen, S; Willemsen, MH, 2022)
"Cyclobenzaprine has potential for sodium channel blockade and ventricular dysrhythmias although cardiac toxicity due to cyclobenzaprine alone is rare."1.42Cardiac sodium channel blockade after an intentional ingestion of lacosamide, cyclobenzaprine, and levetiracetam: Case report. ( Cao, D; Chua-Tuan, JL; Hoyte, CO; Iwanicki, JL, 2015)
"On the average, seizures were observed at 40 mg/kg and were seen after desmethylimipramine (50 mg/kg), mianserin (30 mg/kg), amitriptyline (20 mg/kg), imipramine (40 mg/kg), maprotiline (40 mg/kg), and zimelidine (50 mg/kg)."1.27Comparison of the (pro)convulsive properties of fluvoxamine and clovoxamine with eight other antidepressants in an animal model. ( Bradford, D; Krijzer, F; Snelder, M, 1984)
"According to our convulsion intensity scoring system, these animals have an audiogenic response score (ARS) of 3 and the colony is designated the GEPR-3 colony."1.27Anticonvulsant drugs and the genetically epilepsy-prone rat. ( Dailey, JW; Jobe, PC, 1985)
"Amitriptyline was the most effective antidepressant, attenuating both seizure severity and afterdischarge duration."1.27Acute effects of antidepressants on hippocampal seizures. ( Clifford, DB; Hicks, FG; Rutherford, JL; Zorumski, CF, 1985)
"Amitriptyline was effective on 11 patients, but in two instances, gave rise to an epileptic fit."1.26[EEG and the action of TRH: comparison with amitriptyline]. ( Bianchi, L; Bramanti, P; Di Perri, R; Meduri, M, 1980)
"could increase the risk of seizures."1.26[Convulsive incidents and EEG changes during treatment with tricyclic antidepressive agents]. ( Escande, M; Gayral, L; Golberger, E; Jarrige, A; Kulik, J, 1976)

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-199028 (77.78)18.7374
1990's2 (5.56)18.2507
2000's2 (5.56)29.6817
2010's1 (2.78)24.3611
2020's3 (8.33)2.80

Authors

AuthorsStudies
Miceli, F1
Millevert, C1
Soldovieri, MV1
Mosca, I1
Ambrosino, P1
Carotenuto, L1
Schrader, D1
Lee, HK1
Riviello, J1
Hong, W1
Risen, S1
Emrick, L1
Amin, H1
Ville, D1
Edery, P1
de Bellescize, J1
Michaud, V1
Van-Gils, J1
Goizet, C1
Willemsen, MH1
Kleefstra, T1
Møller, RS1
Bayat, A1
Devinsky, O1
Sands, T1
Korenke, GC1
Kluger, G1
Mefford, HC1
Brilstra, E1
Lesca, G1
Milh, M1
Cooper, EC1
Taglialatela, M1
Weckhuysen, S1
Aydın, Ş1
Kılıç Tatlıcı, C1
Çivgin, ME1
Yazıcı, ZG1
Yıldırım, C1
Dinçer Öner, S1
Kılıç, FS1
McLaren, JR1
Shi, W1
Misko, AL1
Emerton, BC1
Chu, CJ1
Chua-Tuan, JL1
Cao, D1
Iwanicki, JL1
Hoyte, CO1
LEREBOULLET, J1
MANS, J1
SENES, M1
DAVISON, K2
VERGA, G1
BENTE, D1
PFEIFFER, WM1
Sterr, A1
Padberg, F1
Amann, B1
Mergl, R1
Mulert, C1
Juckel, G1
Hegerl, U1
Pogarell, O1
Olesen, OV1
Small, JG1
Small, IF1
Rumpl, E1
Hinterhuber, H1
Ziegler, DK1
Trimble, MR2
Krijzer, F1
Snelder, M1
Bradford, D1
Bramanti, P1
Meduri, M1
Bianchi, L1
Di Perri, R1
Lowry, MR1
Dunner, FJ1
Okiishi, CG1
Paradiso, S1
Robinson, RG1
Vol'f, MSh1
Escande, M1
Gayral, L1
Golberger, E1
Jarrige, A1
Kulik, J1
Glötzner, FL1
Samland, O1
Dommasch, D1
Burcet Darde, J1
Förstl, H1
Zagorski, A1
Pohlmann-Eden, B1
Robertson, MM1
Dailey, JW1
Jobe, PC1
Clifford, DB1
Rutherford, JL1
Hicks, FG1
Zorumski, CF1
Houghton, AW1
Redding, FK1
Palem, RM1
Palem, L1
Hill, RM1
Verniaud, WM1
Horning, MG1
McCulley, LB1
Morgan, NF1
Zuska, K1
Nievoll, A1
Dallos, V1
Heathfield, K1
Scharfetter, C1

Reviews

3 reviews available for amitriptyline and Aura

ArticleYear
An overview of the classification, causes, and treatment of headache.
    Hospital & community psychiatry, 1984, Volume: 35, Issue:3

    Topics: Amitriptyline; Analgesics; Antidepressive Agents, Tricyclic; Biofeedback, Psychology; Cerebrovascula

1984
Epilepsy, antidepressants, and the role of nomifensine.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:4 Pt 2

    Topics: Adult; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Double-Bl

1984
Gender differences in depression associated with neurologic illness: clinical correlates and pharmacologic response.
    The journal of gender-specific medicine : JGSM : the official journal of the Partnership for Women's Health at Columbia, 2001, Volume: 4, Issue:2

    Topics: Alzheimer Disease; Amitriptyline; Antidepressive Agents, Tricyclic; Depression; Epilepsy; Female; Hu

2001

Trials

3 trials available for amitriptyline and Aura

ArticleYear
Epilepsy, antidepressants, and the role of nomifensine.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:4 Pt 2

    Topics: Adult; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Double-Bl

1984
The treatment of depression in patients with epilepsy. A double-blind trial.
    Journal of affective disorders, 1985, Volume: 9, Issue:2

    Topics: Adolescent; Adult; Aged; Amitriptyline; Clinical Trials as Topic; Depressive Disorder; Double-Blind

1985
EEG activation after intravenous amitriptyline.
    Electroencephalography and clinical neurophysiology, 1965, Volume: 19, Issue:3

    Topics: Adolescent; Adult; Aged; Amitriptyline; Clinical Trials as Topic; Depression; Electroencephalography

1965

Other Studies

31 other studies available for amitriptyline and Aura

ArticleYear
KCNQ2 R144 variants cause neurodevelopmental disability with language impairment and autistic features without neonatal seizures through a gain-of-function mechanism.
    EBioMedicine, 2022, Volume: 81

    Topics: Amitriptyline; Autistic Disorder; Epilepsy; Gain of Function Mutation; Humans; Infant, Newborn; Infa

2022
The investigation of antidepressant and anxiolytic effects of pregabalin and its mechanisms of action in rats.
    Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology, 2023, Volume: 35, Issue:4

    Topics: Amitriptyline; Animals; Anti-Anxiety Agents; Antidepressive Agents; Epilepsy; Fluoxetine; Humans; Ke

2023
Hippocampal sharp wave ripples during invasive monitoring: A physiologic finding.
    Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2021, Volume: 132, Issue:5

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Electroencephalography; Epilepsy; Hippocampus; Huma

2021
Cardiac sodium channel blockade after an intentional ingestion of lacosamide, cyclobenzaprine, and levetiracetam: Case report.
    Clinical toxicology (Philadelphia, Pa.), 2015, Volume: 53, Issue:6

    Topics: Acetamides; Adolescent; Amitriptyline; Anticonvulsants; Drug Interactions; Drug Overdose; Electrocar

2015
[THE NEW ANTIEPILEPTIC AGENTS].
    La Revue du praticien, 1963, Dec-09, Volume: 13

    Topics: Acetazolamide; Adrenocorticotropic Hormone; Amitriptyline; Anticonvulsants; Chlordiazepoxide; Dichlo

1963
[AMITRIPTYLINE OR LAROXYL IN DEPRESSIVE SYNDROMES].
    Journal de medecine de Bordeaux et du Sud-Ouest, 1964, Volume: 141

    Topics: Amitriptyline; Bipolar Disorder; Depression; Depressive Disorder; Depressive Disorder, Major; Epilep

1964
EPISODIC DEPERSONALIZATION; OBSERVATIONS ON 7 PATIENTS.
    The British journal of psychiatry : the journal of mental science, 1964, Volume: 110

    Topics: Alcoholic Beverages; Amitriptyline; Amobarbital; Cochlea; Convulsive Therapy; Depersonalization; Dep

1964
[AMITRIPTYLINE IN AMBULATORY PSYCHIATRIC PRACTICE].
    L' Ospedale maggiore, 1964, Volume: 59

    Topics: Amitriptyline; Autonomic Nervous System Diseases; Depression; Drug Eruptions; Drug Hypersensitivity;

1964
[DYNAMIC COURSE CHARACTERISTIC OF AMITRIPTYLINE MEDICATION WITH REGARD TO ELECTROENCEPHALOGRAPHIC FINDINGS].
    Arzneimittel-Forschung, 1964, Volume: 14

    Topics: Affect; Amitriptyline; Electroencephalography; Epilepsy; Psychopharmacology; Schizophrenia; Toxicolo

1964
Electroencephalographic abnormalities associated with antidepressant treatment: a comparison of mirtazapine, venlafaxine, citalopram, reboxetine, and amitriptyline.
    The Journal of clinical psychiatry, 2006, Volume: 67, Issue:2

    Topics: Adult; Amitriptyline; Antidepressive Agents; Cerebral Cortex; Citalopram; Cyclohexanols; Electroence

2006
The influence of disulfiram and calcium carbimide on the serum diphenylhydantoin. Excretion of HPPH in the urine.
    Archives of neurology, 1967, Volume: 16, Issue:6

    Topics: Acetazolamide; Adult; Aged; Alcoholism; Amitriptyline; Chlordiazepoxide; Chlorpromazine; Chromatogra

1967
EEG spikes in non-epileptic psychiatric patients.
    Diseases of the nervous system, 1967, Volume: 28, Issue:8

    Topics: Adolescent; Adult; Aged; Amitriptyline; Antisocial Personality Disorder; Barbiturates; Brain; Brain

1967
Unusual 'spike-wave stupor' in a patient with manic-depressive psychosis treated with amitriptyline.
    Journal of neurology, 1981, Volume: 226, Issue:2

    Topics: Action Potentials; Amitriptyline; Bipolar Disorder; Coma; Electroencephalography; Epilepsy; Humans;

1981
Comparison of the (pro)convulsive properties of fluvoxamine and clovoxamine with eight other antidepressants in an animal model.
    Neuropsychobiology, 1984, Volume: 12, Issue:4

    Topics: Amitriptyline; Animals; Antidepressive Agents; Desipramine; Disease Models, Animal; Dose-Response Re

1984
[EEG and the action of TRH: comparison with amitriptyline].
    Bollettino della Societa italiana di biologia sperimentale, 1980, Dec-15, Volume: 56, Issue:23

    Topics: Adolescent; Adult; Amitriptyline; Electroencephalography; Epilepsy; Female; Humans; Male; Middle Age

1980
Seizures during tricyclic therapy.
    The American journal of psychiatry, 1980, Volume: 137, Issue:11

    Topics: Adolescent; Adult; Aged; Amitriptyline; Depressive Disorder; Electroencephalography; Epilepsy; Femal

1980
[Psychotropic drugs in the clinical picture of epilepsy (review of the literature)].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1975, Volume: 75, Issue:3

    Topics: Amitriptyline; Animals; Anti-Anxiety Agents; Anticonvulsants; Antipsychotic Agents; Carbamazepine; C

1975
[Convulsive incidents and EEG changes during treatment with tricyclic antidepressive agents].
    L'Encephale, 1976, Volume: 2, Issue:2

    Topics: Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Electroencephalography;

1976
[Brain stem seizures with circumscrbed elementary symptoms].
    Der Nervenarzt, 1976, Volume: 47, Issue:9

    Topics: Adult; Amitriptyline; Ataxia; Brain Neoplasms; Brain Stem; Carbamazepine; Epilepsy; Female; Humans;

1976
[Accidental epileptic crises. Importance of drugs and the genetic factor in their presentation].
    Neurologia (Barcelona, Spain), 1992, Volume: 7, Issue:8

    Topics: Adult; Amitriptyline; Epilepsy; Humans; Male; Middle Aged; Theophylline

1992
Somatosensory evoked potentials as indicators of altered cerebral excitability during psychotropic drug treatment.
    Biological psychiatry, 1991, Feb-15, Volume: 29, Issue:4

    Topics: Aged; Amitriptyline; Antidepressive Agents; Arousal; Depressive Disorder; Electroencephalography; Ep

1991
Anticonvulsant drugs and the genetically epilepsy-prone rat.
    Federation proceedings, 1985, Volume: 44, Issue:10

    Topics: Acoustic Stimulation; Amitriptyline; Animals; Anticonvulsants; Carbamazepine; Desipramine; Disease M

1985
Acute effects of antidepressants on hippocampal seizures.
    Annals of neurology, 1985, Volume: 18, Issue:6

    Topics: Amitriptyline; Animals; Anticonvulsants; Antidepressive Agents; Bupropion; Desipramine; Epilepsy; Hi

1985
Convulsions precipitated by amitriptyline.
    Lancet (London, England), 1971, Jan-16, Volume: 1, Issue:7690

    Topics: Adult; Amitriptyline; Electroencephalography; Epilepsy; Humans; Male; Seizures

1971
EEG activation with amitriptyline.
    Electroencephalography and clinical neurophysiology, 1969, Volume: 26, Issue:6

    Topics: Adolescent; Adult; Amitriptyline; Cerebral Cortex; Electroencephalography; Epilepsy; Female; Humans;

1969
[Is the amitriptyline-perphenazine association epileptogenic?].
    Annales medico-psychologiques, 1972, Volume: 2, Issue:4

    Topics: Amitriptyline; Drug Interactions; Electroencephalography; Epilepsy; Humans; Mental Disorders; Perphe

1972
Infants exposed in utero to antiepileptic drugs. A prospective study.
    American journal of diseases of children (1960), 1974, Volume: 127, Issue:5

    Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Amitriptyline; Amniotic Fluid; Anticonvulsants; Chro

1974
[Significance of amitriptyline activation in clinical electroencephalography].
    Ceskoslovenska neurologie, 1970, Volume: 33, Issue:3

    Topics: Adolescent; Adult; Amitriptyline; Child; Electroencephalography; Epilepsy; Female; Humans; Male; Mid

1970
[Therapeutic experiences with oxazepam--a derivative of the benzodiazepine series--in child and adolescent psychiatry].
    Wiener klinische Wochenschrift, 1971, Apr-09, Volume: 83, Issue:14

    Topics: Adolescent; Adolescent Psychiatry; Adult; Aggression; Amitriptyline; Anticonvulsants; Brain Damage,

1971
Iatrogenic epilepsy due to antidepressant drugs.
    British medical journal, 1969, Oct-11, Volume: 4, Issue:5675

    Topics: Adolescent; Adult; Alcoholism; Amitriptyline; Antidepressive Agents; Barbiturates; Brain Damage, Chr

1969
[Poisoning with an antidepressive agent. Status epilepticus in suicidal amitriptyline intoxication. Remarks on the neurology of severe poisonings].
    Archiv fur Psychiatrie und Nervenkrankheiten, 1965, Sep-08, Volume: 207, Issue:2

    Topics: Amitriptyline; Antidepressive Agents; Epilepsy; Humans; Neurologic Manifestations; Pupil; Reflex, St

1965