amitriptyline has been researched along with Aura in 36 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Forty-two patients with depression and epilepsy were entered into an antidepressant trial of amitriptyline, nomifensine and placebo." | 5.05 | The treatment of depression in patients with epilepsy. A double-blind trial. ( Robertson, MM; Trimble, MR, 1985) |
| "Pregabalin (PGB) is used in drug-resistant epilepsy." | 4.31 | The investigation of antidepressant and anxiolytic effects of pregabalin and its mechanisms of action in rats. ( Aydın, Ş; Çivgin, ME; Dinçer Öner, S; Kılıç Tatlıcı, C; Kılıç, FS; Yazıcı, ZG; Yıldırım, C, 2023) |
| "He discusses treatment of headache in relation to management of the acute attack, avoidance of trigger factors, and pharmacological and nonpharmacological prophylaxis." | 2.37 | An overview of the classification, causes, and treatment of headache. ( Ziegler, DK, 1984) |
| "The absence of neonatal seizures is a robust and important clinical differentiator between KCNQ2 gain-of-function and loss-of-function variants." | 1.72 | KCNQ2 R144 variants cause neurodevelopmental disability with language impairment and autistic features without neonatal seizures through a gain-of-function mechanism. ( Ambrosino, P; Amin, H; Bayat, A; Brilstra, E; Carotenuto, L; Cooper, EC; de Bellescize, J; Devinsky, O; Edery, P; Emrick, L; Goizet, C; Hong, W; Kleefstra, T; Kluger, G; Korenke, GC; Lee, HK; Lesca, G; Mefford, HC; Miceli, F; Michaud, V; Milh, M; Millevert, C; Mosca, I; Møller, RS; Risen, S; Riviello, J; Sands, T; Schrader, D; Soldovieri, MV; Taglialatela, M; Van-Gils, J; Ville, D; Weckhuysen, S; Willemsen, MH, 2022) |
| "Cyclobenzaprine has potential for sodium channel blockade and ventricular dysrhythmias although cardiac toxicity due to cyclobenzaprine alone is rare." | 1.42 | Cardiac sodium channel blockade after an intentional ingestion of lacosamide, cyclobenzaprine, and levetiracetam: Case report. ( Cao, D; Chua-Tuan, JL; Hoyte, CO; Iwanicki, JL, 2015) |
| "On the average, seizures were observed at 40 mg/kg and were seen after desmethylimipramine (50 mg/kg), mianserin (30 mg/kg), amitriptyline (20 mg/kg), imipramine (40 mg/kg), maprotiline (40 mg/kg), and zimelidine (50 mg/kg)." | 1.27 | Comparison of the (pro)convulsive properties of fluvoxamine and clovoxamine with eight other antidepressants in an animal model. ( Bradford, D; Krijzer, F; Snelder, M, 1984) |
| "According to our convulsion intensity scoring system, these animals have an audiogenic response score (ARS) of 3 and the colony is designated the GEPR-3 colony." | 1.27 | Anticonvulsant drugs and the genetically epilepsy-prone rat. ( Dailey, JW; Jobe, PC, 1985) |
| "Amitriptyline was the most effective antidepressant, attenuating both seizure severity and afterdischarge duration." | 1.27 | Acute effects of antidepressants on hippocampal seizures. ( Clifford, DB; Hicks, FG; Rutherford, JL; Zorumski, CF, 1985) |
| "Amitriptyline was effective on 11 patients, but in two instances, gave rise to an epileptic fit." | 1.26 | [EEG and the action of TRH: comparison with amitriptyline]. ( Bianchi, L; Bramanti, P; Di Perri, R; Meduri, M, 1980) |
| "could increase the risk of seizures." | 1.26 | [Convulsive incidents and EEG changes during treatment with tricyclic antidepressive agents]. ( Escande, M; Gayral, L; Golberger, E; Jarrige, A; Kulik, J, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 28 (77.78) | 18.7374 |
| 1990's | 2 (5.56) | 18.2507 |
| 2000's | 2 (5.56) | 29.6817 |
| 2010's | 1 (2.78) | 24.3611 |
| 2020's | 3 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Miceli, F | 1 |
| Millevert, C | 1 |
| Soldovieri, MV | 1 |
| Mosca, I | 1 |
| Ambrosino, P | 1 |
| Carotenuto, L | 1 |
| Schrader, D | 1 |
| Lee, HK | 1 |
| Riviello, J | 1 |
| Hong, W | 1 |
| Risen, S | 1 |
| Emrick, L | 1 |
| Amin, H | 1 |
| Ville, D | 1 |
| Edery, P | 1 |
| de Bellescize, J | 1 |
| Michaud, V | 1 |
| Van-Gils, J | 1 |
| Goizet, C | 1 |
| Willemsen, MH | 1 |
| Kleefstra, T | 1 |
| Møller, RS | 1 |
| Bayat, A | 1 |
| Devinsky, O | 1 |
| Sands, T | 1 |
| Korenke, GC | 1 |
| Kluger, G | 1 |
| Mefford, HC | 1 |
| Brilstra, E | 1 |
| Lesca, G | 1 |
| Milh, M | 1 |
| Cooper, EC | 1 |
| Taglialatela, M | 1 |
| Weckhuysen, S | 1 |
| Aydın, Ş | 1 |
| Kılıç Tatlıcı, C | 1 |
| Çivgin, ME | 1 |
| Yazıcı, ZG | 1 |
| Yıldırım, C | 1 |
| Dinçer Öner, S | 1 |
| Kılıç, FS | 1 |
| McLaren, JR | 1 |
| Shi, W | 1 |
| Misko, AL | 1 |
| Emerton, BC | 1 |
| Chu, CJ | 1 |
| Chua-Tuan, JL | 1 |
| Cao, D | 1 |
| Iwanicki, JL | 1 |
| Hoyte, CO | 1 |
| LEREBOULLET, J | 1 |
| MANS, J | 1 |
| SENES, M | 1 |
| DAVISON, K | 2 |
| VERGA, G | 1 |
| BENTE, D | 1 |
| PFEIFFER, WM | 1 |
| Sterr, A | 1 |
| Padberg, F | 1 |
| Amann, B | 1 |
| Mergl, R | 1 |
| Mulert, C | 1 |
| Juckel, G | 1 |
| Hegerl, U | 1 |
| Pogarell, O | 1 |
| Olesen, OV | 1 |
| Small, JG | 1 |
| Small, IF | 1 |
| Rumpl, E | 1 |
| Hinterhuber, H | 1 |
| Ziegler, DK | 1 |
| Trimble, MR | 2 |
| Krijzer, F | 1 |
| Snelder, M | 1 |
| Bradford, D | 1 |
| Bramanti, P | 1 |
| Meduri, M | 1 |
| Bianchi, L | 1 |
| Di Perri, R | 1 |
| Lowry, MR | 1 |
| Dunner, FJ | 1 |
| Okiishi, CG | 1 |
| Paradiso, S | 1 |
| Robinson, RG | 1 |
| Vol'f, MSh | 1 |
| Escande, M | 1 |
| Gayral, L | 1 |
| Golberger, E | 1 |
| Jarrige, A | 1 |
| Kulik, J | 1 |
| Glötzner, FL | 1 |
| Samland, O | 1 |
| Dommasch, D | 1 |
| Burcet Darde, J | 1 |
| Förstl, H | 1 |
| Zagorski, A | 1 |
| Pohlmann-Eden, B | 1 |
| Robertson, MM | 1 |
| Dailey, JW | 1 |
| Jobe, PC | 1 |
| Clifford, DB | 1 |
| Rutherford, JL | 1 |
| Hicks, FG | 1 |
| Zorumski, CF | 1 |
| Houghton, AW | 1 |
| Redding, FK | 1 |
| Palem, RM | 1 |
| Palem, L | 1 |
| Hill, RM | 1 |
| Verniaud, WM | 1 |
| Horning, MG | 1 |
| McCulley, LB | 1 |
| Morgan, NF | 1 |
| Zuska, K | 1 |
| Nievoll, A | 1 |
| Dallos, V | 1 |
| Heathfield, K | 1 |
| Scharfetter, C | 1 |
3 reviews available for amitriptyline and Aura
| Article | Year |
|---|---|
An overview of the classification, causes, and treatment of headache.
Topics: Amitriptyline; Analgesics; Antidepressive Agents, Tricyclic; Biofeedback, Psychology; Cerebrovascula | 1984 |
Epilepsy, antidepressants, and the role of nomifensine.
Topics: Adult; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Double-Bl | 1984 |
Gender differences in depression associated with neurologic illness: clinical correlates and pharmacologic response.
Topics: Alzheimer Disease; Amitriptyline; Antidepressive Agents, Tricyclic; Depression; Epilepsy; Female; Hu | 2001 |
3 trials available for amitriptyline and Aura
| Article | Year |
|---|---|
Epilepsy, antidepressants, and the role of nomifensine.
Topics: Adult; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Double-Bl | 1984 |
The treatment of depression in patients with epilepsy. A double-blind trial.
Topics: Adolescent; Adult; Aged; Amitriptyline; Clinical Trials as Topic; Depressive Disorder; Double-Blind | 1985 |
EEG activation after intravenous amitriptyline.
Topics: Adolescent; Adult; Aged; Amitriptyline; Clinical Trials as Topic; Depression; Electroencephalography | 1965 |
31 other studies available for amitriptyline and Aura
| Article | Year |
|---|---|
KCNQ2 R144 variants cause neurodevelopmental disability with language impairment and autistic features without neonatal seizures through a gain-of-function mechanism.
Topics: Amitriptyline; Autistic Disorder; Epilepsy; Gain of Function Mutation; Humans; Infant, Newborn; Infa | 2022 |
The investigation of antidepressant and anxiolytic effects of pregabalin and its mechanisms of action in rats.
Topics: Amitriptyline; Animals; Anti-Anxiety Agents; Antidepressive Agents; Epilepsy; Fluoxetine; Humans; Ke | 2023 |
Hippocampal sharp wave ripples during invasive monitoring: A physiologic finding.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Electroencephalography; Epilepsy; Hippocampus; Huma | 2021 |
Cardiac sodium channel blockade after an intentional ingestion of lacosamide, cyclobenzaprine, and levetiracetam: Case report.
Topics: Acetamides; Adolescent; Amitriptyline; Anticonvulsants; Drug Interactions; Drug Overdose; Electrocar | 2015 |
[THE NEW ANTIEPILEPTIC AGENTS].
Topics: Acetazolamide; Adrenocorticotropic Hormone; Amitriptyline; Anticonvulsants; Chlordiazepoxide; Dichlo | 1963 |
[AMITRIPTYLINE OR LAROXYL IN DEPRESSIVE SYNDROMES].
Topics: Amitriptyline; Bipolar Disorder; Depression; Depressive Disorder; Depressive Disorder, Major; Epilep | 1964 |
EPISODIC DEPERSONALIZATION; OBSERVATIONS ON 7 PATIENTS.
Topics: Alcoholic Beverages; Amitriptyline; Amobarbital; Cochlea; Convulsive Therapy; Depersonalization; Dep | 1964 |
[AMITRIPTYLINE IN AMBULATORY PSYCHIATRIC PRACTICE].
Topics: Amitriptyline; Autonomic Nervous System Diseases; Depression; Drug Eruptions; Drug Hypersensitivity; | 1964 |
[DYNAMIC COURSE CHARACTERISTIC OF AMITRIPTYLINE MEDICATION WITH REGARD TO ELECTROENCEPHALOGRAPHIC FINDINGS].
Topics: Affect; Amitriptyline; Electroencephalography; Epilepsy; Psychopharmacology; Schizophrenia; Toxicolo | 1964 |
Electroencephalographic abnormalities associated with antidepressant treatment: a comparison of mirtazapine, venlafaxine, citalopram, reboxetine, and amitriptyline.
Topics: Adult; Amitriptyline; Antidepressive Agents; Cerebral Cortex; Citalopram; Cyclohexanols; Electroence | 2006 |
The influence of disulfiram and calcium carbimide on the serum diphenylhydantoin. Excretion of HPPH in the urine.
Topics: Acetazolamide; Adult; Aged; Alcoholism; Amitriptyline; Chlordiazepoxide; Chlorpromazine; Chromatogra | 1967 |
EEG spikes in non-epileptic psychiatric patients.
Topics: Adolescent; Adult; Aged; Amitriptyline; Antisocial Personality Disorder; Barbiturates; Brain; Brain | 1967 |
Unusual 'spike-wave stupor' in a patient with manic-depressive psychosis treated with amitriptyline.
Topics: Action Potentials; Amitriptyline; Bipolar Disorder; Coma; Electroencephalography; Epilepsy; Humans; | 1981 |
Comparison of the (pro)convulsive properties of fluvoxamine and clovoxamine with eight other antidepressants in an animal model.
Topics: Amitriptyline; Animals; Antidepressive Agents; Desipramine; Disease Models, Animal; Dose-Response Re | 1984 |
[EEG and the action of TRH: comparison with amitriptyline].
Topics: Adolescent; Adult; Amitriptyline; Electroencephalography; Epilepsy; Female; Humans; Male; Middle Age | 1980 |
Seizures during tricyclic therapy.
Topics: Adolescent; Adult; Aged; Amitriptyline; Depressive Disorder; Electroencephalography; Epilepsy; Femal | 1980 |
[Psychotropic drugs in the clinical picture of epilepsy (review of the literature)].
Topics: Amitriptyline; Animals; Anti-Anxiety Agents; Anticonvulsants; Antipsychotic Agents; Carbamazepine; C | 1975 |
[Convulsive incidents and EEG changes during treatment with tricyclic antidepressive agents].
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Electroencephalography; | 1976 |
[Brain stem seizures with circumscrbed elementary symptoms].
Topics: Adult; Amitriptyline; Ataxia; Brain Neoplasms; Brain Stem; Carbamazepine; Epilepsy; Female; Humans; | 1976 |
[Accidental epileptic crises. Importance of drugs and the genetic factor in their presentation].
Topics: Adult; Amitriptyline; Epilepsy; Humans; Male; Middle Aged; Theophylline | 1992 |
Somatosensory evoked potentials as indicators of altered cerebral excitability during psychotropic drug treatment.
Topics: Aged; Amitriptyline; Antidepressive Agents; Arousal; Depressive Disorder; Electroencephalography; Ep | 1991 |
Anticonvulsant drugs and the genetically epilepsy-prone rat.
Topics: Acoustic Stimulation; Amitriptyline; Animals; Anticonvulsants; Carbamazepine; Desipramine; Disease M | 1985 |
Acute effects of antidepressants on hippocampal seizures.
Topics: Amitriptyline; Animals; Anticonvulsants; Antidepressive Agents; Bupropion; Desipramine; Epilepsy; Hi | 1985 |
Convulsions precipitated by amitriptyline.
Topics: Adult; Amitriptyline; Electroencephalography; Epilepsy; Humans; Male; Seizures | 1971 |
EEG activation with amitriptyline.
Topics: Adolescent; Adult; Amitriptyline; Cerebral Cortex; Electroencephalography; Epilepsy; Female; Humans; | 1969 |
[Is the amitriptyline-perphenazine association epileptogenic?].
Topics: Amitriptyline; Drug Interactions; Electroencephalography; Epilepsy; Humans; Mental Disorders; Perphe | 1972 |
Infants exposed in utero to antiepileptic drugs. A prospective study.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Amitriptyline; Amniotic Fluid; Anticonvulsants; Chro | 1974 |
[Significance of amitriptyline activation in clinical electroencephalography].
Topics: Adolescent; Adult; Amitriptyline; Child; Electroencephalography; Epilepsy; Female; Humans; Male; Mid | 1970 |
[Therapeutic experiences with oxazepam--a derivative of the benzodiazepine series--in child and adolescent psychiatry].
Topics: Adolescent; Adolescent Psychiatry; Adult; Aggression; Amitriptyline; Anticonvulsants; Brain Damage, | 1971 |
Iatrogenic epilepsy due to antidepressant drugs.
Topics: Adolescent; Adult; Alcoholism; Amitriptyline; Antidepressive Agents; Barbiturates; Brain Damage, Chr | 1969 |
[Poisoning with an antidepressive agent. Status epilepticus in suicidal amitriptyline intoxication. Remarks on the neurology of severe poisonings].
Topics: Amitriptyline; Antidepressive Agents; Epilepsy; Humans; Neurologic Manifestations; Pupil; Reflex, St | 1965 |