amitriptyline has been researched along with Atrioventricular Nodal Re-Entrant Tachycardia in 21 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "However, ventricular tachycardia was detected which did not respond to lidocaine, bicarbonate and cardioversion treatment." | 5.31 | Efficacy of long duration resuscitation and magnesium sulphate treatment in amitriptyline poisoning. ( Citak, A; Karaböcüoğlu, M; Soysal, DD; Uçsel, R; Uzel, N, 2002) |
| "Our data suggest that amitriptyline-induced inhibition of I(Na) unmasks the Brugada ECG phenotype and facilitates development of an arrhythmogenic substrate only in the setting of a genetic predisposition by creating repolarization heterogeneities that give rise to phase 2 reentry and VT." | 3.78 | Ionic and cellular mechanisms underlying the development of acquired Brugada syndrome in patients treated with antidepressants. ( Antzelevitch, C; Barajas-Martínez, H; Di Diego, JM; Hu, D; Minoura, Y; Sicouri, S; Zygmunt, AC, 2012) |
| "In the present case, arrhythmia and circulatory shock responded neither to alkalization and elevated sodium levels after infusion of sodium bicarbonate, nor to any other established therapies." | 1.48 | [Successful lipid rescue therapy in a case of severe amitriptyline/quetiapine intoxication]. ( Fischer, B; Otte, S; Sayk, F, 2018) |
| "Recently, we managed ventricular tachycardia in a young female presented with an impaired consciousness 10 h after intentionally ingesting 2500 mg amitriptyline." | 1.46 | Amitriptyline-induced ventricular tachycardia: a case report. ( Chowdhury, AW; Islam, MS; Kabir, SR; Kawser, S; Sabah, KMN; Saha, BP, 2017) |
| "Amitriptyline has the potential to cause unusual serious complications, such as abdominal compartment syndrome, irreversible central nervous system disability and lethal arrhythmia." | 1.46 | Unusual complications from amitriptyline intoxication. ( Maruguchi, H; Nakao, A; Nakayama, S; Nishimura, T, 2017) |
| "Cyclobenzaprine has potential for sodium channel blockade and ventricular dysrhythmias although cardiac toxicity due to cyclobenzaprine alone is rare." | 1.42 | Cardiac sodium channel blockade after an intentional ingestion of lacosamide, cyclobenzaprine, and levetiracetam: Case report. ( Cao, D; Chua-Tuan, JL; Hoyte, CO; Iwanicki, JL, 2015) |
| "She was in comatose, had generalized tonic clonic seizure, ventricular tachycardia, and wide QRS complexes." | 1.35 | Treatment of severe amitriptyline intoxication with plasmapheresis. ( Akyüz, M; Aydemir, C; Cabuk, H; Eldes, N; Kolsal, E; Numanoglu, V; Piskin, E; Tekin, IO, 2009) |
| "Magnesium sulfate is a very effective treatment in intractable arrhythmias caused by high-dose amitriptyline intoxication." | 1.34 | Efficacy of magnesium sulfate for treatment of ventricular tachycardia in amitriptyline intoxication. ( Babaoglu, K; Barn, E; Gokalp, AS; Sarisoy, O; Tugay, S, 2007) |
| "However, ventricular tachycardia was detected which did not respond to lidocaine, bicarbonate and cardioversion treatment." | 1.31 | Efficacy of long duration resuscitation and magnesium sulphate treatment in amitriptyline poisoning. ( Citak, A; Karaböcüoğlu, M; Soysal, DD; Uçsel, R; Uzel, N, 2002) |
| "After the appearance of ventricular tachycardia, they were treated with magnesium sulfate (45 mg/kg + 15 mg/kg/min) or lidocaine (1 mg/kg + 0." | 1.29 | Effects of magnesium sulfate and lidocaine in the treatment of ventricular arrhythmias in experimental amitriptyline poisoning in the rat. ( Abrahamsson, J; Knudsen, K, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.76) | 18.7374 |
| 1990's | 4 (19.05) | 18.2507 |
| 2000's | 6 (28.57) | 29.6817 |
| 2010's | 7 (33.33) | 24.3611 |
| 2020's | 3 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Garrett, P | 1 |
| Klupfel, S | 1 |
| Ryan, K | 1 |
| Benz, P | 1 |
| Zosel, A | 1 |
| Farkas, A | 1 |
| Theobald, J | 1 |
| Yang, XY | 1 |
| Song, XT | 1 |
| Zhang, Y | 1 |
| Sabah, KMN | 1 |
| Chowdhury, AW | 1 |
| Islam, MS | 1 |
| Saha, BP | 1 |
| Kabir, SR | 1 |
| Kawser, S | 1 |
| Otte, S | 1 |
| Fischer, B | 1 |
| Sayk, F | 1 |
| Nishimura, T | 1 |
| Maruguchi, H | 1 |
| Nakao, A | 1 |
| Nakayama, S | 1 |
| Butt, K | 1 |
| Ambati, S | 1 |
| Chua-Tuan, JL | 1 |
| Cao, D | 1 |
| Iwanicki, JL | 1 |
| Hoyte, CO | 1 |
| Abeyaratne, DD | 1 |
| Liyanapathirana, C | 1 |
| Gamage, A | 1 |
| Karunarathne, P | 1 |
| Botheju, M | 1 |
| Indrakumar, J | 1 |
| Kolsal, E | 1 |
| Tekin, IO | 1 |
| Piskin, E | 1 |
| Aydemir, C | 1 |
| Akyüz, M | 1 |
| Cabuk, H | 1 |
| Eldes, N | 1 |
| Numanoglu, V | 1 |
| Minoura, Y | 1 |
| Di Diego, JM | 1 |
| Barajas-Martínez, H | 1 |
| Zygmunt, AC | 1 |
| Hu, D | 1 |
| Sicouri, S | 1 |
| Antzelevitch, C | 1 |
| Srinivasa, V | 1 |
| Gerner, P | 1 |
| Haderer, A | 1 |
| Abdi, S | 1 |
| Jarolim, P | 1 |
| Wang, GK | 1 |
| LISSAC, J | 1 |
| SAVIER, CH | 1 |
| DUREPAIRE, H | 1 |
| AUZEPY, P | 1 |
| BROCARD, H | 1 |
| Baysal, T | 1 |
| Oran, B | 1 |
| Doğan, M | 1 |
| Cimen, D | 1 |
| Elmas, S | 1 |
| Karaaslan, S | 1 |
| Sarisoy, O | 1 |
| Babaoglu, K | 1 |
| Tugay, S | 1 |
| Barn, E | 1 |
| Gokalp, AS | 1 |
| Algren, DA | 1 |
| Sutter, ME | 1 |
| Ansel, GM | 2 |
| Coyne, K | 1 |
| Arnold, S | 1 |
| Nelson, SD | 2 |
| Meimer, JP | 1 |
| Knudsen, K | 1 |
| Abrahamsson, J | 1 |
| Coumbe, A | 1 |
| Perez-Martinez, AL | 1 |
| Fegan, AW | 1 |
| Hill, IR | 1 |
| Citak, A | 1 |
| Soysal, DD | 1 |
| Uçsel, R | 1 |
| Karaböcüoğlu, M | 1 |
| Uzel, N | 1 |
21 other studies available for amitriptyline and Atrioventricular Nodal Re-Entrant Tachycardia
| Article | Year |
|---|---|
Esmolol for intractable ventricular arrhythmias in major amitriptyline toxicity.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Humans; Propanolamines; Tachy | 2022 |
QTc Prolongation in Poison Center Exposures to CredibleMeds List of Substances with "Known Risk of Torsades de Pointes".
Topics: Amitriptyline; Arrhythmias, Cardiac; Diphenhydramine; Electrocardiography; Flecainide; Humans; Long | 2022 |
Wide QRS Complex Tachycardia With a Dominant R-Wave in Lead aVR-Is It Ventricular Tachycardia?
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Diagnosis, Differential; Doxepin; Drug Overdose; El | 2020 |
Amitriptyline-induced ventricular tachycardia: a case report.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Female; Humans; Suicide, Attempted; Tachycar | 2017 |
[Successful lipid rescue therapy in a case of severe amitriptyline/quetiapine intoxication].
Topics: Adrenergic Uptake Inhibitors; Adult; Amitriptyline; Arrhythmias, Cardiac; Drug Overdose; Female; Hum | 2018 |
Unusual complications from amitriptyline intoxication.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Brain Damage, Chronic; Coma; Humans; Intestinal Obs | 2017 |
A Peculiar Wide Complex Tachycardia.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Cardiotoxicity; Drug Overdose; Electrocardiography; | 2019 |
Cardiac sodium channel blockade after an intentional ingestion of lacosamide, cyclobenzaprine, and levetiracetam: Case report.
Topics: Acetamides; Adolescent; Amitriptyline; Anticonvulsants; Drug Interactions; Drug Overdose; Electrocar | 2015 |
Survival after severe amitriptyline poisoning with prolonged ventricular tachycardia and cardiac arrest.
Topics: Adult; Amitriptyline; Electrocardiography; Female; Heart Arrest; Humans; Pulmonary Edema; Survival A | 2016 |
Treatment of severe amitriptyline intoxication with plasmapheresis.
Topics: Amitriptyline; Child, Preschool; Coma; Drug Overdose; Female; Humans; Plasmapheresis; Poisoning; Sei | 2009 |
Ionic and cellular mechanisms underlying the development of acquired Brugada syndrome in patients treated with antidepressants.
Topics: Action Potentials; Adrenergic beta-Agonists; Amitriptyline; Animals; Anti-Arrhythmia Agents; Antidep | 2012 |
The relative toxicity of amitriptyline, bupivacaine, and levobupivacaine administered as rapid infusions in rats.
Topics: Amitriptyline; Anesthetics, Local; Animals; Antidepressive Agents, Tricyclic; Blood Pressure; Bupiva | 2003 |
[ACUTE INTOXICATION BY AMITRIPTYLINE WITH VENTRICULAR TACHYCARDIA. RECOVERY AFTER CARDIO-RESPIRATORY RESUSCITATION].
Topics: Amitriptyline; Heart; Humans; Poisoning; Resuscitation; Tachycardia; Tachycardia, Ventricular; Toxic | 1965 |
Beta-blocker treatment in an adolescent with amitriptyline intoxication.
Topics: Adolescent; Adrenergic beta-Antagonists; Amitriptyline; Antidepressive Agents, Tricyclic; Coma; Diag | 2007 |
Efficacy of magnesium sulfate for treatment of ventricular tachycardia in amitriptyline intoxication.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Child, Preschool; Humans; Magnesium Sulfate; Male; | 2007 |
Treatment of tricyclic antidepressant cardiac toxicity.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Child, Preschool; Humans; Hydrogen-Ion Concentratio | 2008 |
Mechanisms of ventricular arrhythmia during amitriptyline toxicity.
Topics: Action Potentials; Amitriptyline; Animals; Blood Pressure; Dogs; Female; Heart Conduction System; He | 1993 |
Prevention of tricyclic antidepressant-induced ventricular tachyarrhythmia by a specific bradycardic agent in a canine model.
Topics: Amitriptyline; Animals; Benzazepines; Cardiovascular Agents; Dogs; Electrocardiography; Female; Male | 1994 |
Effects of magnesium sulfate and lidocaine in the treatment of ventricular arrhythmias in experimental amitriptyline poisoning in the rat.
Topics: Amitriptyline; Analysis of Variance; Animals; Blood Pressure; Electrocardiography; Heart Rate; Lidoc | 1994 |
Arrhythmogenic right ventricular dysplasia (ARVD): an overlooked and underdiagnosed condition?
Topics: Adolescent; Amitriptyline; Death, Sudden; Diagnosis, Differential; Drug Overdose; Female; Heart Vent | 1997 |
Efficacy of long duration resuscitation and magnesium sulphate treatment in amitriptyline poisoning.
Topics: Amitriptyline; Anti-Arrhythmia Agents; Antidepressive Agents, Tricyclic; Cardiopulmonary Resuscitati | 2002 |