amitriptyline has been researched along with Atrial Fibrillation in 4 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Atrial Fibrillation: Abnormal cardiac rhythm that is characterized by rapid, uncoordinated firing of electrical impulses in the upper chambers of the heart (HEART ATRIA). In such case, blood cannot be effectively pumped into the lower chambers of the heart (HEART VENTRICLES). It is caused by abnormal impulse generation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The objective of the current report is to describe the case of a previously asymptomatic patient receiving amitriptyline who developed extrapyramidal symptoms within 1 month of initiating concomitant treatment with amiodarone for atrial fibrillation." | 3.76 | Extrapyramidal symptoms with concomitant use of amitriptyline and amiodarone in an elderly patient. ( Pawar, PS; Woo, DA, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pawar, PS | 1 |
| Woo, DA | 1 |
| FEKETE, M | 1 |
| BORSY, J | 1 |
| EDWARDS, AL | 1 |
| Crane, GE | 1 |
1 review available for amitriptyline and Atrial Fibrillation
| Article | Year |
|---|---|
Cardiac toxicity and psychotropic drugs.
Topics: Amitriptyline; Antidepressive Agents; Atrial Fibrillation; Death, Sudden; Electrocardiography; Heart | 1970 |
3 other studies available for amitriptyline and Atrial Fibrillation
| Article | Year |
|---|---|
Extrapyramidal symptoms with concomitant use of amitriptyline and amiodarone in an elderly patient.
Topics: Aged, 80 and over; Amiodarone; Amitriptyline; Anti-Arrhythmia Agents; Antidepressive Agents, Tricycl | 2010 |
ON THE ANTIARRHYTHMIC EFFECT OF SOME THYMOLEPTICS (AMITRIPTYLINE, IMIPRAMINE, TRIMEPROPIMINE AND DESMETHYLIMIPRAMINE).
Topics: Aconitum; Amitriptyline; Antidepressive Agents; Atrial Fibrillation; Bradycardia; Bretylium Compound | 1964 |
IMIPRAMINE MYOCARDIAL TOXICITY.
Topics: Amitriptyline; Atrial Fibrillation; Electrocardiography; Imipramine; Myocardium; Tachycardia; Toxico | 1964 |