amitriptyline has been researched along with Asthma in 13 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Amitriptyline is a drug of high potential, which inhibits acute bronchoconstriction and induces bronchodilatation in pre-contracted airways." | 1.91 | Amitriptyline inhibits bronchoconstriction and directly promotes dilatation of the airways. ( Böll, S; Braunschweig, T; Hempel, P; Klein, V; Martin, C; Michely, A; Rieg, AD; Spillner, J; Tenbrock, K; Verjans, E; von Stillfried, S; Wagner, N, 2023) |
| "Unexplained cough is a diagnosis of exclusion that should not be made until a thorough validated diagnostic evaluation is performed, specific and appropriate validated treatments have been tried and failed, and uncommon causes have been ruled out." | 1.36 | Unexplained cough in the adult. ( Irwin, RS, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (76.92) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Hempel, P | 1 |
| Klein, V | 1 |
| Michely, A | 1 |
| Böll, S | 1 |
| Rieg, AD | 1 |
| Spillner, J | 1 |
| Braunschweig, T | 1 |
| von Stillfried, S | 1 |
| Wagner, N | 1 |
| Martin, C | 1 |
| Tenbrock, K | 1 |
| Verjans, E | 1 |
| Irwin, RS | 1 |
| BATTERMAN, RC | 1 |
| KAUFMAN, JE | 1 |
| MOURATOFF, GJ | 1 |
| Trufakin, VA | 1 |
| Shurlygina, AV | 1 |
| Vondra, V | 2 |
| Růzicka, J | 2 |
| Spicák, V | 1 |
| Kadar, D | 1 |
| Gayral, LF | 1 |
| Ananth, J | 1 |
| Wilson, RC | 1 |
| Sanger, MD | 1 |
| Meares, RA | 1 |
| Mills, JE | 1 |
| Horvath, TB | 1 |
| Atkinson, JM | 1 |
| Pun, LQ | 1 |
| Rand, MJ | 1 |
| Sugihara, H | 1 |
| Ishihara, K | 1 |
| Noguchi, H | 1 |
1 review available for amitriptyline and Asthma
| Article | Year |
|---|---|
[The problems of the central regulation of immune system biorhythms: the role of exogenous and endogenous melatonin].
Topics: Adrenergic Uptake Inhibitors; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Asthma; Circ | 2006 |
2 trials available for amitriptyline and Asthma
| Article | Year |
|---|---|
The treatment of anxiety and depression in the allergic patient.
Topics: Adolescent; Adult; Aged; Amitriptyline; Angioedema; Anxiety; Asthma; Clinical Trials as Topic; Depre | 1969 |
Amitriptyline and asthma.
Topics: Acetylcholine; Adolescent; Adult; Amitriptyline; Animals; Asthma; Clinical Trials as Topic; Guinea P | 1971 |
10 other studies available for amitriptyline and Asthma
| Article | Year |
|---|---|
Amitriptyline inhibits bronchoconstriction and directly promotes dilatation of the airways.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Albuterol; Amitriptyline; Animals; Asthma; Bronchoconstr | 2023 |
Unexplained cough in the adult.
Topics: Adrenergic Uptake Inhibitors; Adult; Amitriptyline; Analgesics, Opioid; Angiotensin-Converting Enzym | 2010 |
CLINICAL USE OF AMITRIPTYLINE FOR THE TREATMENT OF PSYCHONEUROTIC REACTIVE ANXIETY AND DEPRESSION.
Topics: Amitriptyline; Anxiety; Arthritis, Rheumatoid; Asthma; Coronary Disease; Depression; Diabetes Mellit | 1964 |
[Pharmacological protection against bronchospasm in bronchial asthma].
Topics: Adolescent; Adult; Aminophylline; Amitriptyline; Asthma; Bronchial Spasm; Bronchodilator Agents; Cro | 1978 |
Letter: Amitriptyline and isoproterenol: fatal drug combination.
Topics: Adult; Amitriptyline; Asthma; Drug Interactions; Female; Humans; Isoproterenol | 1975 |
[The protective effect of fenoterol, ipratropium bromide and amitriptyline against induced bronchial spasm (author's transl)].
Topics: Adolescent; Adult; Amitriptyline; Asthma; Bronchial Spasm; Ethanolamines; Female; Fenoterol; Humans; | 1975 |
[Tranquillisers in the treatment of psychosomatic diseases].
Topics: Amitriptyline; Asthma; Benzazepines; Benzene Derivatives; Chlordiazepoxide; Colitis, Ulcerative; Dru | 1972 |
Letter: Antiasthmatic effect of amitriptyline.
Topics: Amitriptyline; Asthma; Female; Humans; Middle Aged | 1974 |
Letter: Antiasthmatic effect of amitriptyline.
Topics: Allergens; Amitriptyline; Asthma; Dust; Female; Humans; Menopause; Middle Aged | 1974 |
Clinical experience with amitriptyline (tryptanol) in the treatment of bronchial asthma.
Topics: Adolescent; Adult; Aged; Amitriptyline; Asthma; Child; Child, Preschool; Humans; Middle Aged | 1965 |