amitriptyline has been researched along with Asthenia in 2 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Asthenia: Clinical sign or symptom manifested as debility, or lack or loss of strength and energy.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Within the conditions of the double-blind trial, it appears that long-acting amitriptyline (Diffucaps), given at the dosage of 25 mg at the evening meal, is more active and better tolerated than a dosage of 40 mg of ordinary amitriptyline at bedtime in depressive sleep disorders." | 2.64 | [Double-blind comparison between amitriptyline Diffucaps and ordinary amitriptyline in sleep disorders of depressive origin]. ( Brasseur, R, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| INVERNIZZI, G | 1 |
| Brasseur, R | 1 |
1 trial available for amitriptyline and Asthenia
| Article | Year |
|---|---|
[Double-blind comparison between amitriptyline Diffucaps and ordinary amitriptyline in sleep disorders of depressive origin].
Topics: Amitriptyline; Asthenia; Clinical Trials as Topic; Delayed-Action Preparations; Depression; Female; | 1975 |
1 other study available for amitriptyline and Asthenia
| Article | Year |
|---|---|
[OBSERVATIONS ON THE USE OF PHENYLPYRROLIDINOPENTANE AS AN ANTIASTHENIC AGENT IN TREATMENT WITH PSYCHOPHARMACOLOGICAL DRUGS].
Topics: Amitriptyline; Anxiety; Anxiety Disorders; Asthenia; Bipolar Disorder; Chemical and Drug Induced Liv | 1964 |