amitriptyline has been researched along with Arthritis in 11 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Arthritis: Acute or chronic inflammation of JOINTS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " As the impact of inflammatory pain upon mood-like disorders in animal models is not well known, our objective was to assess whether prolonged experimental monoarthritis (ARTH) induced the development of anxiety and depressive-like behaviours in rodents and if amitriptyline, an antidepressant commonly used in the treatment of chronic pain, could reverse both nociceptive and mood-like impairments." | 7.80 | Amitriptyline reverses hyperalgesia and improves associated mood-like disorders in a model of experimental monoarthritis. ( Almeida, A; Amorim, D; David-Pereira, A; Pertovaara, A; Pinto-Ribeiro, F, 2014) |
| "A case is presented of psoriasis occurring de novo during lithium therapy and progressing to psoriatic arthritis." | 7.67 | Psoriatic arthritis during lithium therapy. ( Skerritt, PW, 1987) |
| " Sprague-Dawley rats with adjuvant-induced arthritis were injected daily for 4 weeks with amitriptyline (10 mg/kg) or imipramine (10 mg/kg) or saline, beginning 21 days after the induction of arthritis." | 7.67 | Reduction of arthritis and pain behaviour following chronic administration of amitriptyline or imipramine in rats with adjuvant-induced arthritis. ( Besson, JM; Butler, SH; Godefroy, F; Weil-Fugazza, J, 1985) |
| " As the impact of inflammatory pain upon mood-like disorders in animal models is not well known, our objective was to assess whether prolonged experimental monoarthritis (ARTH) induced the development of anxiety and depressive-like behaviours in rodents and if amitriptyline, an antidepressant commonly used in the treatment of chronic pain, could reverse both nociceptive and mood-like impairments." | 3.80 | Amitriptyline reverses hyperalgesia and improves associated mood-like disorders in a model of experimental monoarthritis. ( Almeida, A; Amorim, D; David-Pereira, A; Pertovaara, A; Pinto-Ribeiro, F, 2014) |
| "A 63-year-old woman with psoriatic arthritis developed arthralgias and shoulder girdle myalgias which were controlled with amitriptyline." | 3.67 | Giant cell arteritis associated with pericarditis and pancreatic insufficiency in a patient with psoriatic arthritis. ( Clementz, GL; Gold, F; Jalovec, L; Khaiser, N; Zolin, WD, 1989) |
| "A case is presented of psoriasis occurring de novo during lithium therapy and progressing to psoriatic arthritis." | 3.67 | Psoriatic arthritis during lithium therapy. ( Skerritt, PW, 1987) |
| " Sprague-Dawley rats with adjuvant-induced arthritis were injected daily for 4 weeks with amitriptyline (10 mg/kg) or imipramine (10 mg/kg) or saline, beginning 21 days after the induction of arthritis." | 3.67 | Reduction of arthritis and pain behaviour following chronic administration of amitriptyline or imipramine in rats with adjuvant-induced arthritis. ( Besson, JM; Butler, SH; Godefroy, F; Weil-Fugazza, J, 1985) |
| "Safety and postoperative pain, range of motion, and self-reported function were evaluated for 90 days." | 2.76 | Novel drug OMS103HP reduces pain and improves joint motion and function for 90 days after arthroscopic meniscectomy. ( Demopulos, GA; ElAttrache, NS; Fox, DL; Garrett, WE; Hewitt, MS; Kaeding, CC; O'Donnell, JB; Papilion, JD; Ruvuna, F; Skrepnik, NV; Whitaker, JS; Xerogeanes, JW, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (54.55) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (36.36) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Amorim, D | 1 |
| David-Pereira, A | 1 |
| Pertovaara, A | 1 |
| Almeida, A | 1 |
| Pinto-Ribeiro, F | 1 |
| Garrett, WE | 1 |
| Kaeding, CC | 1 |
| ElAttrache, NS | 1 |
| Xerogeanes, JW | 1 |
| Hewitt, MS | 1 |
| Skrepnik, NV | 1 |
| Papilion, JD | 1 |
| O'Donnell, JB | 1 |
| Fox, DL | 1 |
| Ruvuna, F | 1 |
| Whitaker, JS | 1 |
| Demopulos, GA | 1 |
| Siegel, MG | 1 |
| Fischmeister, MF | 1 |
| WRIGHT, F | 1 |
| Egbunike, IG | 1 |
| Chaffee, BJ | 1 |
| Clementz, GL | 1 |
| Gold, F | 1 |
| Khaiser, N | 1 |
| Zolin, WD | 1 |
| Jalovec, L | 1 |
| Skerritt, PW | 1 |
| Godefroy, F | 2 |
| Butler, SH | 2 |
| Weil-Fugazza, J | 2 |
| Besson, JM | 2 |
| Tangri, KK | 1 |
| Saxena, PR | 1 |
| Seth, PK | 1 |
| Bhargava, KP | 1 |
1 review available for amitriptyline and Arthritis
| Article | Year |
|---|---|
Antidepressants in the management of chronic pain syndromes.
Topics: Amitriptyline; Antidepressive Agents; Arthritis; Back Pain; Chronic Disease; Diabetic Neuropathies; | 1990 |
1 trial available for amitriptyline and Arthritis
| Article | Year |
|---|---|
Novel drug OMS103HP reduces pain and improves joint motion and function for 90 days after arthroscopic meniscectomy.
Topics: Adolescent; Adult; Aged; Amitriptyline; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthrosc | 2011 |
9 other studies available for amitriptyline and Arthritis
| Article | Year |
|---|---|
Amitriptyline reverses hyperalgesia and improves associated mood-like disorders in a model of experimental monoarthritis.
Topics: Amitriptyline; Analgesics, Non-Narcotic; Animals; Arthritis; Carrageenan; Disease Models, Animal; Ex | 2014 |
Regarding the novel drug OMS103HP.
Topics: Amitriptyline; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthroscopy; Female; Humans; Keto | 2012 |
Novel drug in arthroscopic meniscectomy.
Topics: Amitriptyline; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthroscopy; Female; Humans; Keto | 2012 |
[Amitryptyline (MK-230) in rheumatology].
Topics: Amitriptyline; Antidepressive Agents; Arthritis; Arthritis, Rheumatoid; Fibromyalgia; Humans; Osteoa | 1962 |
Giant cell arteritis associated with pericarditis and pancreatic insufficiency in a patient with psoriatic arthritis.
Topics: Amitriptyline; Arthritis; Exocrine Pancreatic Insufficiency; Female; Giant Cell Arteritis; Humans; M | 1989 |
Psoriatic arthritis during lithium therapy.
Topics: Adult; Amitriptyline; Arthritis; Bipolar Disorder; Drug Therapy, Combination; Fear; Female; Humans; | 1987 |
Do acute or chronic tricyclic antidepressants modify morphine antinociception in arthritic rats?
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Arthritis; Arthritis, Experimental; Drug S | 1986 |
Reduction of arthritis and pain behaviour following chronic administration of amitriptyline or imipramine in rats with adjuvant-induced arthritis.
Topics: Amitriptyline; Animals; Arthritis; Arthritis, Experimental; Behavior, Animal; Body Weight; Disease M | 1985 |
Anti-inflammatory activity of imipramine and congeners.
Topics: Adenosine Triphosphatases; Alanine Transaminase; Amitriptyline; Animals; Arthritis; Aspartate Aminot | 1966 |