amitriptyline has been researched along with Arthritis, Rheumatoid in 9 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Arthritis, Rheumatoid: A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare the efficacy and tolerability of paroxetine (a selective serotonin reuptake inhibitor) with that of amitriptyline (a tricyclic antidepressant) in the treatment of depression in 191 patients with rheumatoid arthritis (RA)." | 9.09 | Paroxetine versus amitriptyline for treatment of depression associated with rheumatoid arthritis: a randomized, double blind, parallel group study. ( Bird, H; Broggini, M, 2000) |
| "Actions on performance of dextropropoxyphene (DXP) alone and in combination with amitriptyline (AMI), indomethacin (IN), and placebo were compared in 15 patients with rheumatoid arthritis." | 9.06 | Psychomotor performance of patients with rheumatoid arthritis: cross-over comparison of dextropropoxyphene, dextropropoxyphene plus amitriptyline, indomethacin, and placebo. ( Julkunen, H; Mattila, MJ; Saarialho-Kere, U; Seppälä, T, 1988) |
| "Thirty-six patients with definite or classical rheumatoid arthritis participated in a double-blind, randomized, placebo-controlled trial to assess the effectiveness of adding amitriptyline to the treatment regimen for the relief of pain not adequately controlled by non-steroidal anti-inflammatory drugs." | 9.05 | Controlled, double-blind, randomized trial of amitriptyline in relieving articular pain and tenderness in patients with rheumatoid arthritis. ( Bellamy, N; Buchanan, WW; Grace, EM; Kassam, Y, 1985) |
| "To compare the efficacy and tolerability of paroxetine (a selective serotonin reuptake inhibitor) with that of amitriptyline (a tricyclic antidepressant) in the treatment of depression in 191 patients with rheumatoid arthritis (RA)." | 5.09 | Paroxetine versus amitriptyline for treatment of depression associated with rheumatoid arthritis: a randomized, double blind, parallel group study. ( Bird, H; Broggini, M, 2000) |
| "Actions on performance of dextropropoxyphene (DXP) alone and in combination with amitriptyline (AMI), indomethacin (IN), and placebo were compared in 15 patients with rheumatoid arthritis." | 5.06 | Psychomotor performance of patients with rheumatoid arthritis: cross-over comparison of dextropropoxyphene, dextropropoxyphene plus amitriptyline, indomethacin, and placebo. ( Julkunen, H; Mattila, MJ; Saarialho-Kere, U; Seppälä, T, 1988) |
| "Forty-seven patients with definite rheumatoid arthritis (RA) were treated in a 32 week, double blind, crossover trial of amitriptyline, desipramine, trazodone, and placebo." | 5.06 | Antidepressant analgesia in rheumatoid arthritis. ( Atwood, C; Beck, NC; Brownlee-Duffeck, M; Elliott, TR; Frank, RG; Haut, AE; Kashani, JH; Kay, DR; Parker, JC; Smith, E, 1988) |
| "Thirty-six patients with definite or classical rheumatoid arthritis participated in a double-blind, randomized, placebo-controlled trial to assess the effectiveness of adding amitriptyline to the treatment regimen for the relief of pain not adequately controlled by non-steroidal anti-inflammatory drugs." | 5.05 | Controlled, double-blind, randomized trial of amitriptyline in relieving articular pain and tenderness in patients with rheumatoid arthritis. ( Bellamy, N; Buchanan, WW; Grace, EM; Kassam, Y, 1985) |
| "The role of amitriptyline in musculoskeletal pain is not as clearly defined as in classical neuropathic pain conditions." | 4.95 | Amitriptyline for musculoskeletal complaints: a systematic review. ( Bierma-Zeinstra, SMA; Bindels, PJE; Schiphof, D; van den Driest, JJ, 2017) |
| "Rheumatoid arthritis is a chronic autoimmune disease hallmarked by inflammation in synovial joints." | 1.46 | Regulation of Arthritis Severity by the Acid Sphingomyelinase. ( Becker, JU; Becker, KA; Beckmann, N; Carpinteiro, A; Fassbender, K; Göthert, JR; Gulbins, E; Hessler, G; Kramer, M; Walter, S; Weber, S, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| van den Driest, JJ | 1 |
| Bierma-Zeinstra, SMA | 1 |
| Bindels, PJE | 1 |
| Schiphof, D | 1 |
| Beckmann, N | 1 |
| Becker, KA | 1 |
| Walter, S | 1 |
| Becker, JU | 1 |
| Kramer, M | 1 |
| Hessler, G | 1 |
| Weber, S | 1 |
| Göthert, JR | 1 |
| Fassbender, K | 1 |
| Gulbins, E | 1 |
| Carpinteiro, A | 1 |
| WRIGHT, F | 1 |
| BATTERMAN, RC | 1 |
| KAUFMAN, JE | 1 |
| MOURATOFF, GJ | 1 |
| Bird, H | 1 |
| Broggini, M | 1 |
| Saarialho-Kere, U | 1 |
| Julkunen, H | 1 |
| Mattila, MJ | 1 |
| Seppälä, T | 1 |
| Frank, RG | 1 |
| Kashani, JH | 1 |
| Parker, JC | 1 |
| Beck, NC | 1 |
| Brownlee-Duffeck, M | 1 |
| Elliott, TR | 1 |
| Haut, AE | 1 |
| Atwood, C | 1 |
| Smith, E | 1 |
| Kay, DR | 1 |
| Grace, EM | 1 |
| Bellamy, N | 1 |
| Kassam, Y | 1 |
| Buchanan, WW | 1 |
| McBride, WW | 1 |
| Dodson, WH | 1 |
| Bennett, JC | 1 |
1 review available for amitriptyline and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Amitriptyline for musculoskeletal complaints: a systematic review.
Topics: Amitriptyline; Analgesics, Non-Narcotic; Arthritis, Rheumatoid; Humans; Low Back Pain; Musculoskelet | 2017 |
4 trials available for amitriptyline and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Paroxetine versus amitriptyline for treatment of depression associated with rheumatoid arthritis: a randomized, double blind, parallel group study.
Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents; Arthritis, Rheumatoid; Depression; Do | 2000 |
Psychomotor performance of patients with rheumatoid arthritis: cross-over comparison of dextropropoxyphene, dextropropoxyphene plus amitriptyline, indomethacin, and placebo.
Topics: Adult; Aged; Amitriptyline; Arthritis, Rheumatoid; Clinical Trials as Topic; Dextropropoxyphene; Dru | 1988 |
Antidepressant analgesia in rheumatoid arthritis.
Topics: Aged; Amitriptyline; Antidepressive Agents; Arthritis, Rheumatoid; Depression; Desipramine; Double-B | 1988 |
Controlled, double-blind, randomized trial of amitriptyline in relieving articular pain and tenderness in patients with rheumatoid arthritis.
Topics: Adult; Aged; Amitriptyline; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Fe | 1985 |
4 other studies available for amitriptyline and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Regulation of Arthritis Severity by the Acid Sphingomyelinase.
Topics: Amitriptyline; Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Disease Models, Animal; Gene | 2017 |
[Amitryptyline (MK-230) in rheumatology].
Topics: Amitriptyline; Antidepressive Agents; Arthritis; Arthritis, Rheumatoid; Fibromyalgia; Humans; Osteoa | 1962 |
CLINICAL USE OF AMITRIPTYLINE FOR THE TREATMENT OF PSYCHONEUROTIC REACTIVE ANXIETY AND DEPRESSION.
Topics: Amitriptyline; Anxiety; Arthritis, Rheumatoid; Asthma; Coronary Disease; Depression; Diabetes Mellit | 1964 |
Management of rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Amitriptyline; Anxiety; Arthritis, Rheumatoid; Aspirin; Attitude of Health | 1969 |