amitriptyline has been researched along with Arthritis, Degenerative in 5 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Using in silico docking analysis, RT-PCR, siRNA, elisa, proteomics and clinical data mining of drug consumption, we explored the clinical relevance of amitriptyline blockade of TLR4-mediated innate immune responses in human osteoarthritis chondrocytes." | 8.12 | Amitriptyline blocks innate immune responses mediated by toll-like receptor 4 and IL-1 receptor: Preclinical and clinical evidence in osteoarthritis and gout. ( Alonso-Pérez, A; Belén Bravo, S; Crespo-Golmar, A; Franco-Trepat, E; Gómez Bahamonde, R; Gualillo, O; Guillán-Fresco, M; Jorge-Mora, A; López-Fagúndez, M; Pazos-Pérez, A, 2022) |
| "Using in silico docking analysis, RT-PCR, siRNA, elisa, proteomics and clinical data mining of drug consumption, we explored the clinical relevance of amitriptyline blockade of TLR4-mediated innate immune responses in human osteoarthritis chondrocytes." | 4.12 | Amitriptyline blocks innate immune responses mediated by toll-like receptor 4 and IL-1 receptor: Preclinical and clinical evidence in osteoarthritis and gout. ( Alonso-Pérez, A; Belén Bravo, S; Crespo-Golmar, A; Franco-Trepat, E; Gómez Bahamonde, R; Gualillo, O; Guillán-Fresco, M; Jorge-Mora, A; López-Fagúndez, M; Pazos-Pérez, A, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 2 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| Franco-Trepat, E | 1 |
| Alonso-Pérez, A | 1 |
| Guillán-Fresco, M | 1 |
| Jorge-Mora, A | 1 |
| Crespo-Golmar, A | 1 |
| López-Fagúndez, M | 1 |
| Pazos-Pérez, A | 1 |
| Gualillo, O | 1 |
| Belén Bravo, S | 1 |
| Gómez Bahamonde, R | 1 |
| Coetzee, R | 1 |
| Johnson, Y | 1 |
| van Niekerk, J | 1 |
| Namane, M | 1 |
| Wielage, R | 1 |
| Bansal, M | 1 |
| Wilson, K | 1 |
| Klein, R | 1 |
| Happich, M | 1 |
| WRIGHT, F | 1 |
| BATTERMAN, RC | 1 |
| KAUFMAN, JE | 1 |
| MOURATOFF, GJ | 1 |
1 review available for amitriptyline and Arthritis, Degenerative
| Article | Year |
|---|---|
Cost-effectiveness of duloxetine in chronic low back pain: a Quebec societal perspective.
Topics: Age Factors; Aged; Amitriptyline; Analgesics; Cardiovascular Diseases; Celecoxib; Chronic Disease; C | 2013 |
4 other studies available for amitriptyline and Arthritis, Degenerative
| Article | Year |
|---|---|
Amitriptyline blocks innate immune responses mediated by toll-like receptor 4 and IL-1 receptor: Preclinical and clinical evidence in osteoarthritis and gout.
Topics: Aged; Amitriptyline; Chondrocytes; Gout; Humans; Immunity, Innate; NLR Family, Pyrin Domain-Containi | 2022 |
Amitriptyline prescribing in public sector healthcare facilities in the Western Cape, South Africa.
Topics: Adult; Aged; Aged, 80 and over; Amitriptyline; Analgesics, Non-Narcotic; Chronic Pain; Female; Hospi | 2020 |
[Amitryptyline (MK-230) in rheumatology].
Topics: Amitriptyline; Antidepressive Agents; Arthritis; Arthritis, Rheumatoid; Fibromyalgia; Humans; Osteoa | 1962 |
CLINICAL USE OF AMITRIPTYLINE FOR THE TREATMENT OF PSYCHONEUROTIC REACTIVE ANXIETY AND DEPRESSION.
Topics: Amitriptyline; Anxiety; Arthritis, Rheumatoid; Asthma; Coronary Disease; Depression; Diabetes Mellit | 1964 |