amitriptyline has been researched along with Anterior Horn Cell Disease in 2 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| " However, 3 patients, receiving amythryptiline in dosage 50 mg/day, experienced side effects (constipation, accommodation disturbances, dry mouth, sleepiness and poor concentration)." | 2.71 | [Pharmacological therapy of sialorrhea in patients with motor neuron disease]. ( Alekhin, AV; Koneva, ON; Levitskiĭ, GN; Morgunova, MS; Serdiuk, AV; Skvortsova, VI, 2005) |
| "Drooling is a distressing symptom for adults with neurological conditions and can be challenging for health professionals." | 2.48 | The management of drooling in adults with neurological conditions. ( Rowson, J; Squires, N; Wills, A, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Squires, N | 1 |
| Wills, A | 1 |
| Rowson, J | 1 |
| Levitskiĭ, GN | 1 |
| Alekhin, AV | 1 |
| Serdiuk, AV | 1 |
| Morgunova, MS | 1 |
| Koneva, ON | 1 |
| Skvortsova, VI | 1 |
1 review available for amitriptyline and Anterior Horn Cell Disease
| Article | Year |
|---|---|
The management of drooling in adults with neurological conditions.
Topics: Administration, Cutaneous; Adult; Amitriptyline; Atropine; Behavior Therapy; Botulinum Toxins, Type | 2012 |
1 trial available for amitriptyline and Anterior Horn Cell Disease
| Article | Year |
|---|---|
[Pharmacological therapy of sialorrhea in patients with motor neuron disease].
Topics: Adrenergic Uptake Inhibitors; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Botulinum Toxin | 2005 |