Page last updated: 2024-10-22

amitriptyline and Anasarca

amitriptyline has been researched along with Anasarca in 14 studies

Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.

Research Excerpts

ExcerptRelevanceReference
"The anti-inflammatory activity of amitriptyline, diazepam and a new, Russian tranquilizer mebicar was studied in a wide range of therapeutic doses on carrageenan-induced paw edema in rats."7.77[Anti-inflammatory effects of amitriptyline, diazepam and mebicar using model of acute carrageenan-induced paw edema in rats]. ( Kaziakhmetova, VN; Valeeva, IKh; Ziganshina, LE, 2011)
"Single and multiple doses of amitriptyline were administered to rats submitted to the carrageenan-induced paw edema model."7.76Amitriptyline and acute inflammation: a study using intravital microscopy and the carrageenan-induced paw edema model. ( Alves, GJ; Palermo-Neto, J; Vismari, L, 2010)
"The present study was designed to further investigate the effect of amitriptyline, a classical tricyclic antidepressant, on carrageenan-induced paw edema in rats."7.76The role of central mechanisms in the anti-inflammatory effect of amitriptyline on carrageenan-induced paw edema in rats. ( Hajhashemi, V; Minaiyan, M; Movahedian, A; Sadeghi, H; Talebi, A, 2010)
" The present study examined the effects of combinations of dextromethorphan and ketamine, two clinically used N-methyl-D-aspartate (NMDA) receptor antagonists, with amitriptyline on formalin-evoked behaviors and paw edema."7.72Peripheral interactions between dextromethorphan, ketamine and amitriptyline on formalin-evoked behaviors and paw edema in rats. ( Reid, A; Sawynok, J, 2003)
"The anti-inflammatory activity of amitriptyline, diazepam and a new, Russian tranquilizer mebicar was studied in a wide range of therapeutic doses on carrageenan-induced paw edema in rats."3.77[Anti-inflammatory effects of amitriptyline, diazepam and mebicar using model of acute carrageenan-induced paw edema in rats]. ( Kaziakhmetova, VN; Valeeva, IKh; Ziganshina, LE, 2011)
"Single and multiple doses of amitriptyline were administered to rats submitted to the carrageenan-induced paw edema model."3.76Amitriptyline and acute inflammation: a study using intravital microscopy and the carrageenan-induced paw edema model. ( Alves, GJ; Palermo-Neto, J; Vismari, L, 2010)
"The present study was designed to further investigate the effect of amitriptyline, a classical tricyclic antidepressant, on carrageenan-induced paw edema in rats."3.76The role of central mechanisms in the anti-inflammatory effect of amitriptyline on carrageenan-induced paw edema in rats. ( Hajhashemi, V; Minaiyan, M; Movahedian, A; Sadeghi, H; Talebi, A, 2010)
" The present study examined the effects of combinations of dextromethorphan and ketamine, two clinically used N-methyl-D-aspartate (NMDA) receptor antagonists, with amitriptyline on formalin-evoked behaviors and paw edema."3.72Peripheral interactions between dextromethorphan, ketamine and amitriptyline on formalin-evoked behaviors and paw edema in rats. ( Reid, A; Sawynok, J, 2003)
"The authors assessed the participants' postoperative pain by means of a visual analog scale at four, six, eight, 12, 24 and 48 hours."2.76Evaluation of the muscle relaxant cyclobenzaprine after third-molar extraction. ( Calazans, AC; de Oliveira E Silva, ED; de Santana Santos, T; Gomes, AC; Martins-Filho, PR; Silva, LC, 2011)
"Gemcitabine is a nucleosid analog approved for use in the treatment of metastatic urothelial carcinoma of the bladder."1.32Gemcitabine-associated scleroderma-like changes of the lower extremities. ( Bessis, D; Guilhou, JJ; Guillot, B; Legouffe, E, 2004)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19903 (21.43)18.7374
1990's0 (0.00)18.2507
2000's3 (21.43)29.6817
2010's8 (57.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Raldi, FV1
Nascimento, RD1
Sato, FRL1
Santos, LM1
Amorim, JBO1
de Moraes, MB1
Calixto-Campos, C1
Zarpelon, AC1
Corrêa, M1
Cardoso, RD1
Pinho-Ribeiro, FA1
Cecchini, R1
Moreira, EG1
Crespigio, J1
Bernardy, CC1
Casagrande, R1
Verri, WA1
Vismari, L2
Alves, GJ2
Palermo-Neto, J2
Hajhashemi, V2
Sadeghi, H2
Minaiyan, M2
Movahedian, A2
Talebi, A2
de Santana Santos, T1
Calazans, AC1
Martins-Filho, PR1
Silva, LC1
de Oliveira E Silva, ED1
Gomes, AC1
Muscará, MN1
Kaziakhmetova, VN1
Valeeva, IKh1
Ziganshina, LE1
Sawynok, J2
Reid, A2
Oatway, M1
Bessis, D1
Guillot, B1
Legouffe, E1
Guilhou, JJ1
Lippmann, W1
Martelli, EA1
Tóth, E1
Segre, AD1
Corsico, N1
Child, JA1

Trials

1 trial available for amitriptyline and Anasarca

ArticleYear
Evaluation of the muscle relaxant cyclobenzaprine after third-molar extraction.
    Journal of the American Dental Association (1939), 2011, Volume: 142, Issue:10

    Topics: Acetaminophen; Adolescent; Adult; Amitriptyline; Analgesics, Non-Narcotic; Double-Blind Method; Edem

2011

Other Studies

13 other studies available for amitriptyline and Anasarca

ArticleYear
Evaluation of the impact of preoperative use of dexamethasone and cyclobenzaprine in surgical extraction of lower third molars on trismus by electromyographic analysis.
    Oral and maxillofacial surgery, 2019, Volume: 23, Issue:4

    Topics: Amitriptyline; Dexamethasone; Edema; Humans; Molar, Third; Pain, Postoperative; Prospective Studies;

2019
The Ehrlich tumor induces pain-like behavior in mice: a novel model of cancer pain for pathophysiological studies and pharmacological screening.
    BioMed research international, 2013, Volume: 2013

    Topics: Amitriptyline; Animals; Behavior, Animal; Carcinoma, Ehrlich Tumor; Cell Proliferation; Disease Mode

2013
Amitriptyline and acute inflammation: a study using intravital microscopy and the carrageenan-induced paw edema model.
    Pharmacology, 2010, Volume: 86, Issue:4

    Topics: Amitriptyline; Animals; Anti-Inflammatory Agents; Carrageenan; Disease Models, Animal; Edema; Half-L

2010
The role of central mechanisms in the anti-inflammatory effect of amitriptyline on carrageenan-induced paw edema in rats.
    Clinics (Sao Paulo, Brazil), 2010, Volume: 65, Issue:11

    Topics: Adrenergic alpha-1 Receptor Antagonists; Amitriptyline; Animals; Anti-Inflammatory Agents; Carrageen

2010
A study on the mechanisms involving the anti-inflammatory effect of amitriptyline in carrageenan-induced paw edema in rats.
    European journal of pharmacology, 2011, Sep-30, Volume: 667, Issue:1-3

    Topics: Amitriptyline; Animals; Anti-Inflammatory Agents; Carrageenan; Edema; Extremities; Inflammation; Inf

2011
A possible role to nitric oxide in the anti-inflammatory effects of amitriptyline.
    Immunopharmacology and immunotoxicology, 2012, Volume: 34, Issue:4

    Topics: Amitriptyline; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Tricyclic; C

2012
[Anti-inflammatory effects of amitriptyline, diazepam and mebicar using model of acute carrageenan-induced paw edema in rats].
    Eksperimental'naia i klinicheskaia farmakologiia, 2011, Volume: 74, Issue:12

    Topics: Amitriptyline; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biureas; Carrageenan; Diazepam; Dis

2011
Peripheral interactions between dextromethorphan, ketamine and amitriptyline on formalin-evoked behaviors and paw edema in rats.
    Pain, 2003, Volume: 102, Issue:1-2

    Topics: Amitriptyline; Analgesics, Non-Narcotic; Animals; Behavior, Animal; Dextromethorphan; Dose-Response

2003
Peripheral antihyperalgesic and analgesic actions of ketamine and amitriptyline in a model of mild thermal injury in the rat.
    Anesthesia and analgesia, 2003, Volume: 97, Issue:1

    Topics: Administration, Topical; Amitriptyline; Anesthetics, Dissociative; Animals; Antidepressive Agents, T

2003
Gemcitabine-associated scleroderma-like changes of the lower extremities.
    Journal of the American Academy of Dermatology, 2004, Volume: 51, Issue:2 Suppl

    Topics: Acetaminophen; Amitriptyline; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy

2004
Blockade of norepinephrine uptake and other activities of 5-(3'-dimethylaminopropyl)-dibenzo(a,d) (1,4)cycloheptadiene hydrochloride (AY-8794) and structurally related compounds.
    Biochemical pharmacology, 1969, Volume: 18, Issue:10

    Topics: Adipose Tissue; Amitriptyline; Animals; Anti-Inflammatory Agents; Biological Transport; Carrageenan;

1969
Mechanism of inhibition of experimental inflammation by antidepressant drugs.
    European journal of pharmacology, 1967, Volume: 2, Issue:3

    Topics: Amitriptyline; Animals; Antidepressive Agents; Carrageenan; Catecholamines; Desipramine; Dextrans; D

1967
Massive oedema and ascites during treatment with anti-depressant drugs.
    Postgraduate medical journal, 1969, Volume: 45, Issue:522

    Topics: Amitriptyline; Antidepressive Agents; Ascites; Diazepam; Edema; Female; Humans; Isocarboxazid; Middl

1969