amitriptyline has been researched along with Alveolitis, Fibrosing in 5 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment of pulmonary fibrosis caused by paraquat (PQ) poisoning remains problematic." | 8.31 | Therapeutic potential of amitriptyline for paraquat-induced pulmonary fibrosis: Involvement of caveolin-1-mediated anti-epithelial-mesenchymal transition and inhibition of apoptosis. ( Chen, J; Cheng, B; Jian, X; Li, C, 2023) |
| "Amitriptyline is a tricyclic antidepressant that was suggested to have antifibrotic potential." | 5.51 | Amitriptyline attenuates bleomycin-induced pulmonary fibrosis: modulation of the expression of NF-κβ, iNOS, and Nrf2. ( Abdelhamid, AM; Haridy, AR; Zaafan, MA, 2019) |
| "Treatment of pulmonary fibrosis caused by paraquat (PQ) poisoning remains problematic." | 4.31 | Therapeutic potential of amitriptyline for paraquat-induced pulmonary fibrosis: Involvement of caveolin-1-mediated anti-epithelial-mesenchymal transition and inhibition of apoptosis. ( Chen, J; Cheng, B; Jian, X; Li, C, 2023) |
| "Amitriptyline is a tricyclic antidepressant that was suggested to have antifibrotic potential." | 1.51 | Amitriptyline attenuates bleomycin-induced pulmonary fibrosis: modulation of the expression of NF-κβ, iNOS, and Nrf2. ( Abdelhamid, AM; Haridy, AR; Zaafan, MA, 2019) |
| " However this increased prescribing was not specific to any particular class of antidepressant or individual drug, and there was no evidence of a dose-response relationship between exposure to amitriptyline (the most commonly prescribed antidepressant) and disease." | 1.31 | Exposure to antidepressants and the risk of cryptogenic fibrosing alveolitis: a case-control study. ( Britton, J; Hubbard, R; Venn, A, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, J | 1 |
| Jian, X | 1 |
| Li, C | 1 |
| Cheng, B | 1 |
| Zaafan, MA | 1 |
| Haridy, AR | 1 |
| Abdelhamid, AM | 1 |
| Ziobro, R | 1 |
| Henry, B | 1 |
| Edwards, MJ | 1 |
| Lentsch, AB | 1 |
| Gulbins, E | 1 |
| Matek, W | 1 |
| Rösch, W | 1 |
| Becker, V | 1 |
| Hubbard, R | 1 |
| Venn, A | 1 |
| Britton, J | 1 |
5 other studies available for amitriptyline and Alveolitis, Fibrosing
| Article | Year |
|---|---|
Therapeutic potential of amitriptyline for paraquat-induced pulmonary fibrosis: Involvement of caveolin-1-mediated anti-epithelial-mesenchymal transition and inhibition of apoptosis.
Topics: Amitriptyline; Animals; Apoptosis; Cadherins; Caveolin 1; Interleukin-17; Lung; Mice; Mice, Inbred C | 2023 |
Amitriptyline attenuates bleomycin-induced pulmonary fibrosis: modulation of the expression of NF-κβ, iNOS, and Nrf2.
Topics: Amitriptyline; Animals; Bleomycin; Lung; Male; NF-E2-Related Factor 2; NF-kappa B; Nitric Oxide Synt | 2019 |
Ceramide mediates lung fibrosis in cystic fibrosis.
Topics: Adrenergic Uptake Inhibitors; Amitriptyline; Animals; Ceramides; Cystic Fibrosis; Cystic Fibrosis Tr | 2013 |
[Pathological changes in lungs and liver after therapy of ulcerative colitis].
Topics: Amitriptyline; Chlordiazepoxide; Colitis, Ulcerative; Humans; Jaundice; Male; Middle Aged; Penicilla | 1980 |
Exposure to antidepressants and the risk of cryptogenic fibrosing alveolitis: a case-control study.
Topics: Aged; Amitriptyline; Antidepressive Agents; Antidepressive Agents, Tricyclic; Case-Control Studies; | 2000 |