amitriptyline has been researched along with Alcoholic Liver Diseases in 2 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| " There was about a fourfold accumulation of the drug in plasma on multiple dosing, corresponding to an effective half-life of 18 hours." | 2.70 | Cyclobenzaprine pharmacokinetics, including the effects of age, gender, and hepatic insufficiency. ( Chavez-Eng, CM; Constanzer, ML; King, JD; Korn, SH; Winchell, GA, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fernandez, A | 1 |
| Matias, N | 1 |
| Fucho, R | 1 |
| Ribas, V | 1 |
| Von Montfort, C | 1 |
| Nuño, N | 1 |
| Baulies, A | 1 |
| Martinez, L | 1 |
| Tarrats, N | 1 |
| Mari, M | 1 |
| Colell, A | 1 |
| Morales, A | 1 |
| Dubuquoy, L | 1 |
| Mathurin, P | 1 |
| Bataller, R | 1 |
| Caballeria, J | 1 |
| Elena, M | 1 |
| Balsinde, J | 1 |
| Kaplowitz, N | 1 |
| Garcia-Ruiz, C | 1 |
| Fernandez-Checa, JC | 1 |
| Winchell, GA | 1 |
| King, JD | 1 |
| Chavez-Eng, CM | 1 |
| Constanzer, ML | 1 |
| Korn, SH | 1 |
1 trial available for amitriptyline and Alcoholic Liver Diseases
| Article | Year |
|---|---|
Cyclobenzaprine pharmacokinetics, including the effects of age, gender, and hepatic insufficiency.
Topics: Administration, Oral; Adult; Age Factors; Aged; Amitriptyline; Analysis of Variance; Area Under Curv | 2002 |
1 other study available for amitriptyline and Alcoholic Liver Diseases
| Article | Year |
|---|---|
ASMase is required for chronic alcohol induced hepatic endoplasmic reticulum stress and mitochondrial cholesterol loading.
Topics: Amitriptyline; Animals; Cholesterol; Disease Models, Animal; Endoplasmic Reticulum Stress; Hepatitis | 2013 |