amitriptyline has been researched along with Alcohol Abuse in 51 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "90 patients with alcoholism stage II suffering from secondary affective disorders (anxiety, depression) were divided into 4 groups: treated with GABA-B-receptor ligand baclofen (group 1), with sibazon (group 2), amitriptylin (group 3), placebo (group 4)." | 9.07 | [The use of baclofen for treating affective disorders in alcoholism]. ( Borodkin, IuS; Burakov, AM; Grinenko, AIa; Ivanov, VB; Karandashova, GF; Krupitskiĭ, EM; Lapin, IP, 1994) |
| "Mirtazapine was tolerated better than amitriptyline treatment." | 6.73 | Effectiveness and tolerability of mirtazapine and amitriptyline in alcoholic patients with co-morbid depressive disorder: a randomized, double-blind study. ( Akdeniz, F; Altintoprak, AE; Coskunol, H; Kitapcioglu, G; Zorlu, N, 2008) |
| "90 patients with alcoholism stage II suffering from secondary affective disorders (anxiety, depression) were divided into 4 groups: treated with GABA-B-receptor ligand baclofen (group 1), with sibazon (group 2), amitriptylin (group 3), placebo (group 4)." | 5.07 | [The use of baclofen for treating affective disorders in alcoholism]. ( Borodkin, IuS; Burakov, AM; Grinenko, AIa; Ivanov, VB; Karandashova, GF; Krupitskiĭ, EM; Lapin, IP, 1994) |
| "Mirtazapine was tolerated better than amitriptyline treatment." | 2.73 | Effectiveness and tolerability of mirtazapine and amitriptyline in alcoholic patients with co-morbid depressive disorder: a randomized, double-blind study. ( Akdeniz, F; Altintoprak, AE; Coskunol, H; Kitapcioglu, G; Zorlu, N, 2008) |
| "The drug also decreased alcohol addiction, had vegetostabilising and sedative effects." | 2.68 | [The efficacy and mechanisms of action of lerivon in alcoholism]. ( Anokhina, IP; Chirko, VV; Ivanets, NN; Kogan, BM; Nebarakova, TP; Rusinov, AV, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 38 (74.51) | 18.7374 |
| 1990's | 6 (11.76) | 18.2507 |
| 2000's | 5 (9.80) | 29.6817 |
| 2010's | 1 (1.96) | 24.3611 |
| 2020's | 1 (1.96) | 2.80 |
| Authors | Studies |
|---|---|
| Greene, MC | 1 |
| Kane, J | 1 |
| Alto, M | 1 |
| Giusto, A | 1 |
| Lovero, K | 1 |
| Stockton, M | 1 |
| McClendon, J | 1 |
| Nicholson, T | 1 |
| Wainberg, ML | 1 |
| Johnson, RM | 1 |
| Tol, WA | 1 |
| Scanlon, KA | 1 |
| Stoppacher, R | 1 |
| Blum, LM | 1 |
| Starkey, SJ | 1 |
| Stiakakis, I | 1 |
| Belivanis, SD | 1 |
| Tzatzarakis, MN | 1 |
| Fragoulis, M | 1 |
| Tsatsakis, AM | 1 |
| Litvintsev, SV | 1 |
| Reznik, AM | 1 |
| Arbuzov, AL | 1 |
| Kutushev, OT | 1 |
| Martyniuk, IuL | 1 |
| Khurbatova, IG | 1 |
| GREENFIELD, AR | 2 |
| OHNELL, LK | 1 |
| Schürks, M | 1 |
| Overlack, M | 1 |
| Bonnet, U | 1 |
| Buonopane, A | 1 |
| Petrakis, IL | 1 |
| Altintoprak, AE | 1 |
| Zorlu, N | 1 |
| Coskunol, H | 1 |
| Akdeniz, F | 1 |
| Kitapcioglu, G | 1 |
| Arnold, OH | 1 |
| Krypsin-Exner, K | 1 |
| Olesen, OV | 1 |
| Gamburg, AL | 1 |
| Aranovich, AG | 1 |
| Rasniuk, VA | 1 |
| Vol'fson, VL | 1 |
| Sandoz, M | 1 |
| Vandel, S | 1 |
| Vandel, B | 1 |
| Bonin, B | 1 |
| Allers, G | 1 |
| Volmat, R | 1 |
| Maany, I | 1 |
| Hayashida, M | 1 |
| Pfeffer, SL | 1 |
| Kron, RE | 1 |
| Busch, KT | 1 |
| Schulz, H | 1 |
| Schou, M | 1 |
| Krupitskiĭ, EM | 2 |
| Burakov, AM | 3 |
| Ivanov, VB | 2 |
| Karandashova, GF | 1 |
| Lapin, IP | 2 |
| Grinenko, AIa | 2 |
| Borodkin, IuS | 2 |
| Krupitsky, EM | 1 |
| Krandashova, GF | 1 |
| Ivanets, NN | 1 |
| Anokhina, IP | 1 |
| Kogan, BM | 1 |
| Chirko, VV | 1 |
| Nebarakova, TP | 1 |
| Rusinov, AV | 1 |
| Rosenbaum, AH | 1 |
| Niven, RG | 1 |
| Hanson, NP | 1 |
| Swanson, DW | 1 |
| Pinder, RM | 1 |
| Brogden, RN | 1 |
| Speight, TM | 1 |
| Avery, GS | 1 |
| Huapaya, LV | 1 |
| Hasenbush, LL | 1 |
| Petit, JM | 1 |
| Spiker, DG | 1 |
| Biggs, JT | 1 |
| Kluger, NJ | 1 |
| Clifford, JS | 1 |
| Cavanagh, RJ | 1 |
| Griffith, WL | 1 |
| Rickels, K | 1 |
| Feighner, JP | 1 |
| Smith, WT | 1 |
| Brahams, D | 1 |
| Lôo, H | 1 |
| Malka, R | 1 |
| Defrance, R | 1 |
| Barrucand, D | 1 |
| Benard, JY | 1 |
| Niox-Rivière, H | 1 |
| Raab, A | 1 |
| Sarda, A | 1 |
| Vachonfrance, G | 1 |
| Kamoun, A | 1 |
| MacCallum, WA | 2 |
| Fava, GA | 1 |
| Lisansky, J | 1 |
| Kellner, R | 1 |
| Zielezny, M | 1 |
| Gol'dovskaia, IL | 1 |
| Hollister, LE | 1 |
| Kashiwagi, T | 1 |
| McClure, JN | 1 |
| Wetzel, RD | 1 |
| Richou, H | 1 |
| Overall, JE | 1 |
| Brown, D | 1 |
| Williams, JD | 1 |
| Neill, LT | 1 |
| Charnoff, SM | 1 |
| Kissin, B | 1 |
| Gross, MM | 1 |
| Chaftez, ME | 1 |
| Rawson, RA | 1 |
| Lipscomb, WR | 1 |
| Rozynko, J | 1 |
| Braasch, F | 1 |
| Bolzani, L | 1 |
| Slivar, G | 1 |
| Boleloucky-Bolen, P | 1 |
| Hofmann, G | 1 |
| Post, F | 1 |
| Dallos, V | 1 |
| Heathfield, K | 1 |
| Rosengren, E | 1 |
| Frederiksen, K | 1 |
4 reviews available for amitriptyline and Alcohol Abuse
| Article | Year |
|---|---|
Psychosocial and pharmacologic interventions to reduce harmful alcohol use in low- and middle-income countries.
Topics: Acamprosate; Alcoholism; Amitriptyline; Developing Countries; Disulfiram; Humans; Male; Mirtazapine; | 2023 |
Pharmacotherapy of alcohol use disorders.
Topics: Acamprosate; Alcohol Deterrents; Alcoholism; Amitriptyline; Antidepressive Agents, Tricyclic; Comorb | 2005 |
Doxepin up-to-date: a review of its pharmacological properties and therapeutic efficacy with particular reference to depression.
Topics: Alcoholism; Amitriptyline; Animals; Anxiety; Cardiovascular Diseases; Depression; Doxepin; Drug Inte | 1977 |
Drugs in the treatment of alcoholism.
Topics: Alcohol Deterrents; Alcoholic Intoxication; Alcoholism; Amitriptyline; Antidepressive Agents; Chlord | 1967 |
13 trials available for amitriptyline and Alcohol Abuse
| Article | Year |
|---|---|
[Correction of affective disorders in patients with alcohol dependence].
Topics: Adult; Alcoholism; Amitriptyline; Antidepressive Agents, Second-Generation; Antidepressive Agents, T | 2002 |
Effectiveness and tolerability of mirtazapine and amitriptyline in alcoholic patients with co-morbid depressive disorder: a randomized, double-blind study.
Topics: Adult; Alcoholism; Amitriptyline; Antidepressive Agents, Tricyclic; Depressive Disorder; Double-Blin | 2008 |
[The use of baclofen for treating affective disorders in alcoholism].
Topics: Adult; Alcoholism; Amitriptyline; Baclofen; Diazepam; Drug Evaluation; Humans; Ligands; Mood Disorde | 1994 |
Baclofen administration for the treatment of affective disorders in alcoholic patients.
Topics: Administration, Oral; Adult; Alcoholism; Amitriptyline; Anxiety Disorders; Baclofen; Blood Platelets | 1993 |
[Effect of pharmacotherapy of affective disorders on the psycho-semantics of alcoholic patients].
Topics: Alcoholism; Amitriptyline; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Baclofen; Color Pe | 1995 |
[The efficacy and mechanisms of action of lerivon in alcoholism].
Topics: Adolescent; Adult; Alcohol Deterrents; Alcoholism; Amitriptyline; Anti-Anxiety Agents; Antidepressiv | 1996 |
Alprazolam, amitriptyline, doxepin, and placebo in the treatment of depression.
Topics: Adult; Alcoholism; Alprazolam; Ambulatory Care; Amitriptyline; Anti-Anxiety Agents; Benzodiazepines; | 1985 |
Tianeptine and amitriptyline. Controlled double-blind trial in depressed alcoholic patients.
Topics: Adult; Alcoholism; Amitriptyline; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Depres | 1988 |
Doxepin hydrochloride.
Topics: Alcoholism; Amitriptyline; Anxiety; Clinical Trials as Topic; Depression; Doxepin; Drug Evaluation; | 1974 |
Drug treatment of anxiety and depression in detoxified alcoholic patients.
Topics: Alcoholism; Amitriptyline; Analysis of Variance; Anxiety; Ascorbic Acid; Chlordiazepoxide; Depressio | 1973 |
Long-term treatment of alcoholism with amitriptyline and emylcamate. A double-blind evaluation.
Topics: Alcoholism; Amitriptyline; Carbamates; Clinical Trials as Topic; Follow-Up Studies; Humans; Placebos | 1967 |
Drug therapy in alcoholism.
Topics: Alcoholic Intoxication; Alcoholism; Amitriptyline; Antidepressive Agents; Benactyzine; Carbamates; C | 1968 |
[Clinical study of an anxiolytic antidepressive drug].
Topics: Adjustment Disorders; Adult; Aged; Alcoholism; Amitriptyline; Bipolar Disorder; Chlordiazepoxide; Cl | 1967 |
34 other studies available for amitriptyline and Alcohol Abuse
| Article | Year |
|---|---|
Comprehensive Duloxetine Analysis in a Fatal Overdose.
Topics: Aged; Alcoholism; Amitriptyline; Depression; Diphenhydramine; Drug Overdose; Duloxetine Hydrochlorid | 2016 |
Disputed case of homicide by smothering due to severe amitriptyline intoxication of the victim.
Topics: Adult; Alcoholism; Amitriptyline; Antidepressive Agents, Tricyclic; Asphyxia; Contusions; Facial Inj | 2009 |
Control of alcoholic agitation and depression with perphenazine and amitriptyline combined.
Topics: Alcoholism; Amitriptyline; Antidepressive Agents; Depression; Depressive Disorder; Humans; Perphenaz | 1963 |
CONTROL OF ALCOHOLIC AGITATION AND DEPRESSION.
Topics: Alcoholism; Amitriptyline; Anxiety; Anxiety Disorders; Depression; Depressive Disorder; Humans; Perp | 1963 |
[EXPERIMENTS WITH AMITRIPTYLINE IN ALCOHOLISM].
Topics: Alcoholism; Amitriptyline; Depression; Depressive Disorder; Humans; Sweden | 1964 |
Naltrexone treatment of combined alcohol and opioid dependence: deterioration of co-morbid major depression.
Topics: Alcoholism; Amitriptyline; Depressive Disorder, Major; Ethanol; Humans; Male; Middle Aged; Morphine; | 2005 |
[Spontaneous and experimental delirium].
Topics: Alcoholism; Amitriptyline; Brain; Delirium; Hallucinations; Hallucinogens; Humans; Judgment; Psychos | 1966 |
The influence of disulfiram and calcium carbimide on the serum diphenylhydantoin. Excretion of HPPH in the urine.
Topics: Acetazolamide; Adult; Aged; Alcoholism; Amitriptyline; Chlordiazepoxide; Chlorpromazine; Chromatogra | 1967 |
[Therapeutic indications for high dosage of oxazepam].
Topics: Alcoholism; Amitriptyline; Dibenzazepines; Humans; Hypnotics and Sedatives; Mental Disorders; Methot | 1967 |
[Various aspects of current treatment of patients with alcoholic delirium].
Topics: Adult; Alcoholism; Amitriptyline; Disulfiram; Fluphenazine; Humans; Male; Methotrimeprazine; Middle | 1983 |
Biotransformation of amitriptyline in alcoholic depressive patients.
Topics: Adult; Aged; Alcoholism; Amitriptyline; Biotransformation; Dealkylation; Depressive Disorder; Female | 1983 |
Possible toxic interaction between disulfiram and amitriptyline.
Topics: Adult; Alcoholism; Amitriptyline; Depressive Disorder; Disulfiram; Drug Interactions; Humans; Male; | 1982 |
[The acute psychiatric emergency].
Topics: Acute Disease; Aged; Alcoholism; Amitriptyline; Brain Ischemia; Cognition Disorders; Consciousness D | 1981 |
Mortality-lowering effect of prophylactic lithium treatment: a look at the evidence.
Topics: Alcoholism; Amitriptyline; Bipolar Disorder; Carbamazepine; Humans; Lithium; Mortality; Suicide | 1995 |
Tardive dyskinesia: relationship with a primary affective disorder.
Topics: Adult; Affective Symptoms; Aged; Alcoholism; Amitriptyline; Antipsychotic Agents; Chlordiazepoxide; | 1977 |
Seven cases of somnambulism induced by drugs.
Topics: Adult; Alcoholism; Amitriptyline; Chlorprothixene; Depression; Drug Therapy, Combination; Ethchlorvy | 1979 |
Successful brief therapy of a retired elderly man with intractable pain, depression, and drug and alcohol dependence.
Topics: Aged; Alcoholism; Amitriptyline; Compulsive Personality Disorder; Dependent Personality Disorder; De | 1977 |
Psychiatric diagnosis and tricyclic plasma levels in 36 hospitalized overdose patients.
Topics: Adjustment Disorders; Adolescent; Adult; Affective Symptoms; Age Factors; Alcoholism; Amitriptyline; | 1976 |
A case of a chemically dependent patient with a thalamic pain syndrome treated with amitriptyline.
Topics: Alcoholism; Amitriptyline; Cerebral Infarction; Flurazepam; Follow-Up Studies; Humans; Male; Middle | 1991 |
Prescribing safety precautions recommended for general practice.
Topics: Adult; Alcoholism; Amitriptyline; Beer; Drug Prescriptions; England; Family Practice; Female; Forens | 1986 |
Disulfiram and antidepressants.
Topics: Alcoholism; Amitriptyline; Disulfiram; Drug Interactions; Humans | 1986 |
Treatment responses in primary and secondary melancholia: a preliminary report.
Topics: Adult; Alcoholism; Amitriptyline; Depressive Disorder; Female; Hospitalization; Humans; Male; Obsess | 1985 |
Drug interactions in aloholism treatment.
Topics: Alcoholism; Amitriptyline; Cyanides; Disulfiram; Drug Synergism; Humans | 1969 |
[Drug therapy of alcoholics].
Topics: Alcoholism; Amitriptyline; Antidepressive Agents; Humans; Opipramol; Phenothiazines; Time Factors | 1974 |
[The possibilities and limitations of psychotropic drug therapy for patients with glaucoma].
Topics: Aged; Alcoholism; Amitriptyline; Antidepressive Agents; Bipolar Disorder; Chronic Disease; Dementia; | 1974 |
Headache and psychiatric disorders.
Topics: Adolescent; Adult; Affective Symptoms; Age Factors; Aged; Alcoholism; Amitriptyline; Antisocial Pers | 1972 |
[Value, in day hospitals, of intravenous perfusions of amitriptyline].
Topics: Adjustment Disorders; Alcoholism; Amitriptyline; Anxiety; Day Care, Medical; Depression; Drug Tolera | 1972 |
Acute delirium in amitriptyline-perphenazine therapy of alcoholism.
Topics: Acute Disease; Adult; Alcoholism; Amitriptyline; Delirium; Diazepam; Drug Combinations; Hallucinatio | 1971 |
[Therapy of agitated depression using Saroten retard 75 and psychopathologic reflexions on the disease].
Topics: Alcoholism; Amitriptyline; Delayed-Action Preparations; Depression; Female; Humans; Middle Aged; Par | 1971 |
[Delirious syndrome in connection with treatment and overdosis (SMV) amitriptyline].
Topics: Adult; Age Factors; Aged; Alcoholism; Amitriptyline; Central Nervous System Diseases; Delirium; Fema | 1968 |
Management of senile psychiatric disorders.
Topics: Adjustment Disorders; Affective Symptoms; Aged; Alcoholism; Amitriptyline; Dementia; Depressive Diso | 1968 |
Iatrogenic epilepsy due to antidepressant drugs.
Topics: Adolescent; Adult; Alcoholism; Amitriptyline; Antidepressive Agents; Barbiturates; Brain Damage, Chr | 1969 |
[Treatment of alcoholics with amitriptyline].
Topics: Alcoholism; Amitriptyline; Humans | 1966 |
[Amitriptyline and alcohol--a commentary].
Topics: Alcoholism; Amitriptyline; Depression; Humans | 1966 |