amitriptyline has been researched along with Akinetic-Rigid Variant of Huntington Disease in 5 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cong, WN | 1 |
| Chadwick, W | 1 |
| Wang, R | 1 |
| Daimon, CM | 1 |
| Cai, H | 1 |
| Amma, J | 1 |
| Wood, WH | 1 |
| Becker, KG | 1 |
| Martin, B | 1 |
| Maudsley, S | 1 |
| Kantor, S | 1 |
| Varga, J | 1 |
| Morton, AJ | 1 |
| Jardri, R | 1 |
| Medjkane, F | 1 |
| Cuisset, JM | 1 |
| Vallee, L | 1 |
| Delion, P | 1 |
| Goeb, JL | 1 |
| Folstein, S | 1 |
| Folstein, M | 1 |
| Glaeser, BS | 1 |
| Vogel, WH | 1 |
| Oleweiler, DB | 1 |
| Hare, TA | 1 |
5 other studies available for amitriptyline and Akinetic-Rigid Variant of Huntington Disease
| Article | Year |
|---|---|
Amitriptyline improves motor function via enhanced neurotrophin signaling and mitochondrial functions in the murine N171-82Q Huntington disease model.
Topics: Amitriptyline; Animals; Brain-Derived Neurotrophic Factor; Computational Biology; Disease Models, An | 2015 |
A single dose of hypnotic corrects sleep and EEG abnormalities in symptomatic Huntington's disease mice.
Topics: Amitriptyline; Animals; Arousal; Behavior, Animal; Dose-Response Relationship, Drug; Electroencephal | 2016 |
Huntington's disease presenting as a depressive disorder with psychotic features.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Child; Depressive Disorder; Diagnosis, Differential | 2007 |
Diagnosis and treatment of Huntington's disease.
Topics: Affective Symptoms; Amitriptyline; Chlorpromazine; Cognition Disorders; Counseling; Deglutition Diso | 1981 |
GABA levels in cerebrospinal fluid of patients with Huntington's chorea: a preliminary report.
Topics: Adult; Aged; Aminobutyrates; Amitriptyline; Chlorpromazine; Diazepam; Female; gamma-Aminobutyric Aci | 1975 |