amitriptyline has been researched along with Aggression in 32 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Aggression: Behavior which may be manifested by destructive and attacking action which is verbal or physical, by covert attitudes of hostility or by obstructionism.
| Excerpt | Relevance | Reference |
|---|---|---|
| " An analogous potentiation of clonidine-induced aggressiveness was obtained with chronic administration (the schedule as above) of levomepromazine (2 mg/kg) or thioridazine (5 mg/kg) but not of spiperone (0." | 5.26 | Chronic treatment with antidepressants: protentiation of clonidine-induced aggression in mice via noradrenergic mechanism. ( Klimek, V; Kordecka-Magiera, A; Maj, J; Mogilnicka, E, 1981) |
| " Renal dosing for topiramate, reduction in PIMs/anticholinergic burden, and substituting haloperidol for olanzapine resolved his violent behavior and CD." | 2.50 | Capgras delusion with violent behavior in Alzheimer dementia: case analysis with literature review. ( Dawood, A; Kaufman, KR; Newman, NB, 2014) |
| ", systemic subcutaneous administration and microinjection into the medial amygdala were employed to examine the effect of chronic administration of psychotropic drugs on muricide in olfactory bulbectomized rats." | 1.27 | Effects of chronic administration of antidepressants on mouse-killing behavior (muricide) in olfactory bulbectomized rats. ( Nakanishi, H; Shibata, S; Ueki, S; Watanabe, S, 1984) |
| " An analogous potentiation of clonidine-induced aggressiveness was obtained with chronic administration (the schedule as above) of levomepromazine (2 mg/kg) or thioridazine (5 mg/kg) but not of spiperone (0." | 1.26 | Chronic treatment with antidepressants: protentiation of clonidine-induced aggression in mice via noradrenergic mechanism. ( Klimek, V; Kordecka-Magiera, A; Maj, J; Mogilnicka, E, 1981) |
| "Maprotiline in particular was more efficacious than any of the other compounds in preventing or suppressing aggressiveness after chronic treatment at doses inactive upon acute administration." | 1.26 | The effects of antidepressants on aggressiveness induced by social deprivation in mice. ( Delini-Stula, A; Vassout, A, 1981) |
| "Maprotiline was more potent than anitriptyline and imipramine in antagonizing haloperidol-induced catalepsy as well as in suppressing muricide induced by either olfactory bulbectomy or delta-9-tetrahydrocannabinol in rats." | 1.25 | [Behavior pharmacology of maprotiline, a new antidepressant]. ( Fujiwara, M; Ibii, N; Inoue, K; Kataoka, Y; Ueki, S, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (81.25) | 18.7374 |
| 1990's | 5 (15.63) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (3.13) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Geyer, HM | 1 |
| Martin, LL | 1 |
| Crichlow, CA | 1 |
| Dekow, FW | 1 |
| Ellis, DB | 1 |
| Kruse, H | 1 |
| Setescak, LL | 1 |
| Worm, M | 1 |
| Kaufman, KR | 1 |
| Newman, NB | 1 |
| Dawood, A | 1 |
| Da Vanzo, JP | 1 |
| Daugherty, M | 1 |
| Ruckart, R | 1 |
| Kang, L | 1 |
| Hara, C | 1 |
| Watanabe, S | 2 |
| Ueki, S | 3 |
| Maj, J | 1 |
| Mogilnicka, E | 2 |
| Klimek, V | 1 |
| Kordecka-Magiera, A | 1 |
| Warrington, SJ | 1 |
| Ankier, SI | 1 |
| Turner, P | 1 |
| Shibata, S | 1 |
| Nakanishi, H | 1 |
| Eisenstein, N | 1 |
| Iorio, LC | 1 |
| Clody, DE | 1 |
| Przewłocka, B | 1 |
| Delini-Stula, A | 1 |
| Vassout, A | 1 |
| Cai, B | 1 |
| Matsumoto, K | 1 |
| Ohta, H | 1 |
| Watanabe, H | 1 |
| Levy, F | 1 |
| Einfeld, S | 1 |
| Looi, J | 1 |
| Rich, MR | 1 |
| Wenzl, H | 1 |
| Graf, E | 1 |
| Sieck, A | 1 |
| Yepes, LE | 1 |
| Balka, EB | 1 |
| Winsberg, BG | 1 |
| Bialer, I | 1 |
| Leaf, RC | 1 |
| Wnek, DJ | 1 |
| Lamon, S | 1 |
| Gay, PE | 1 |
| Rampling, D | 1 |
| Fujiwara, M | 1 |
| Inoue, K | 1 |
| Kataoka, Y | 1 |
| Ibii, N | 1 |
| Burov, IuV | 1 |
| Salimov, RM | 1 |
| Langee, HR | 1 |
| Conlon, M | 1 |
| Szlabowicz, JW | 1 |
| Stewart, JT | 1 |
| Soloff, PH | 1 |
| George, A | 1 |
| Nathan, RS | 1 |
| Schulz, PM | 1 |
| Perel, JM | 1 |
| Niho, T | 1 |
| Ito, C | 1 |
| Shibutani, Y | 1 |
| Hashizume, H | 1 |
| Yamaguchi, K | 1 |
| Jackson, RD | 1 |
| Corrigan, JD | 1 |
| Arnett, JA | 1 |
| Ferrini, R | 1 |
| Miragoli, G | 1 |
| Zetler, G | 1 |
| Otten, U | 1 |
| Deberdt, R | 1 |
| Vakhing, VA | 1 |
| Allikmets, LKh | 1 |
| Mekhilane, LS | 1 |
| Theorell, T | 1 |
| Sallou, C | 1 |
| Senault, B | 1 |
| Nievoll, A | 1 |
1 review available for amitriptyline and Aggression
| Article | Year |
|---|---|
Capgras delusion with violent behavior in Alzheimer dementia: case analysis with literature review.
Topics: Aged; Aggression; Alzheimer Disease; Amitriptyline; Anticonvulsants; Antidepressive Agents, Tricycli | 2014 |
3 trials available for amitriptyline and Aggression
| Article | Year |
|---|---|
An evaluation of possible interactions between ethanol and trazodone or amitriptyline.
Topics: Adult; Aggression; Amitriptyline; Drug Interactions; Ethanol; Female; Flicker Fusion; Humans; Kineti | 1984 |
Amitriptyline and methylphenidate treatment of behaviorally disordered children.
Topics: Aggression; Amitriptyline; Attention; Child; Child Behavior Disorders; Clinical Trials as Topic; Hum | 1977 |
Paradoxical effects of amitriptyline on borderline patients.
Topics: Aggression; Amitriptyline; Borderline Personality Disorder; Clinical Trials as Topic; Double-Blind M | 1986 |
28 other studies available for amitriptyline and Aggression
| Article | Year |
|---|---|
(+/-)-4-Aryl-4,5-dihydro-3H-1,3-benzodiazepines. 1. Synthesis and evaluation of (+/-)-4,5-dihydro-2,3-dimethyl-4-phenyl-3H-1,3-benzodiazepine and analogues as potential antidepressant agents.
Topics: Aggression; Animals; Antidepressive Agents; Benzodiazepines; Biogenic Amines; Chemical Phenomena; Ch | 1982 |
Pharmacological and biochemical studies in isolation-induced fighting mice.
Topics: Aggression; Amitriptyline; Amphetamine; Analgesics; Animals; Anticonvulsants; Antidepressive Agents; | 1966 |
Effects of psychotropic drugs microinjected into the hypothalamus on muricide, catalepsy and cortical EEG in OB rats.
Topics: Aggression; Amitriptyline; Animals; Atropine; Cerebral Cortex; Chlordiazepoxide; Chlorpromazine; Evo | 1983 |
Chronic treatment with antidepressants: protentiation of clonidine-induced aggression in mice via noradrenergic mechanism.
Topics: Aggression; Amitriptyline; Animals; Antidepressive Agents; Brompheniramine; Clonidine; Drug Synergis | 1981 |
Effects of chronic administration of antidepressants on mouse-killing behavior (muricide) in olfactory bulbectomized rats.
Topics: Aggression; Amitriptyline; Amygdala; Animals; Antidepressive Agents; Chlorpromazine; Clomipramine; D | 1984 |
Role of serotonin in the blockade of muricidal behavior by tricyclic antidepressants.
Topics: Aggression; Amitriptyline; Amphetamines; Animals; Desipramine; Diet; Humans; Imipramine; Male; Mice; | 1982 |
Facilitated shock-induced aggression after chronic treatment with antidepressant drugs in the rat.
Topics: Aggression; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Electroshock; Humans; Imiprami | 1981 |
The effects of antidepressants on aggressiveness induced by social deprivation in mice.
Topics: Aggression; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Clomipramine; Humans; Imiprami | 1981 |
Biphasic effects of typical antidepressants and mianserin, an atypical antidepressant, on aggressive behavior in socially isolated mice.
Topics: Aggression; Amitriptyline; Animals; Antidepressive Agents; Brain Chemistry; Clomipramine; Male; Mapr | 1993 |
Combined pharmacotherapy or polypharmacy?
Topics: Aggression; Akathisia, Drug-Induced; Amitriptyline; Antidepressive Agents, Tricyclic; Attention Defi | 1996 |
Animal behavior case of the month. Evaluation of aggression when food was present.
Topics: Aggression; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Behavior Therapy; Dogs; Feedin | 1999 |
Central nervous effects of a new tricyclic antidepressant (amitriptylinoxide).
Topics: Aggression; Amitriptyline; Animals; Anticonvulsants; Avoidance Learning; Body Temperature; Central N | 1978 |
Despite various drugs, cats continue to kill mice.
Topics: Aggression; Amitriptyline; Amphetamine; Animals; Avoidance Learning; Cats; Conditioning, Operant; De | 1978 |
Aggression: a paradoxical response to tricyclic antidepressants.
Topics: Adult; Aggression; Amitriptyline; Antidepressive Agents, Tricyclic; Diazepam; Female; Humans; Imipra | 1978 |
[Behavior pharmacology of maprotiline, a new antidepressant].
Topics: Aggression; Amitriptyline; Animals; Anthracenes; Apomorphine; Behavior, Animal; Body Temperature; Ca | 1975 |
[The effect of pharmacologic substances on intraspecies aggression].
Topics: Aggression; Amitriptyline; Animals; Benactyzine; Chlordiazepoxide; Chlorpromazine; Diazepam; Haloper | 1975 |
Predictors of response to antidepressant medications.
Topics: Aggression; Amitriptyline; Antidepressive Agents; Depression; Doxepin; Follow-Up Studies; Humans; In | 1992 |
Amitriptyline treatment of agitation associated with anoxic encephalopathy.
Topics: Adult; Aggression; Amitriptyline; Cognition Disorders; Confusion; Humans; Hypoxia, Brain; Male; Myoc | 1990 |
[Pharmacological properties of MO-8282, a novel antidepressant].
Topics: Aggression; Amitriptyline; Animals; Antidepressive Agents; Behavior, Animal; Biogenic Amines; Brain; | 1986 |
Amitriptyline for agitation in head injury.
Topics: Adult; Aggression; Amitriptyline; Brain Injuries; Female; Humans; Psychomotor Agitation | 1985 |
[Effect of glaziovine on exploratory activity of aggressive mice in the so-called "holey board" test].
Topics: Aggression; Amitriptyline; Animals; Anti-Anxiety Agents; Aporphines; Ascorbic Acid; Behavior, Animal | 1974 |
[Aggressiveness of the rat following combined treatment with monomaime oxidase inhibitors and other psychotropic drugs, especially thymoleptics].
Topics: Aggression; Alkaloids; Amitriptyline; Amphetamine; Animals; Anthracenes; Body Temperature; Central N | 1969 |
Lorazepam in the treatment of severe anxiety and anxiety associated with psychotic conditions.
Topics: Adult; Aggression; Amitriptyline; Anxiety Disorders; Ataxia; Benzodiazepinones; Bipolar Disorder; Ch | 1973 |
[Effect of antidepressants and neuroleptics on emotional reactions caused by cholinergic stimulation of the hypothalamus and mesencephalon].
Topics: Acetylcholine; Aggression; Amitriptyline; Animals; Antidepressive Agents; Benactyzine; Cats; Chlordi | 1972 |
[Impressions from a psychosomatic congress in the USA].
Topics: Aggression; Amitriptyline; Growth Hormone; Humans; Monoamine Oxidase; Psychophysiologic Disorders | 1971 |
[Effect of amitryptyline drops, in ambulatory therapy, on behavior and character disorders in children and adolescents].
Topics: Adolescent; Aggression; Amitriptyline; Character; Child; Child Behavior Disorders; Child, Preschool; | 1969 |
[Intraspecific aggressive behavior induced by apomorphine in the rat].
Topics: Acepromazine; Age Factors; Aggression; Amitriptyline; Animals; Apomorphine; Atropine; Behavior, Anim | 1970 |
[Therapeutic experiences with oxazepam--a derivative of the benzodiazepine series--in child and adolescent psychiatry].
Topics: Adolescent; Adolescent Psychiatry; Adult; Aggression; Amitriptyline; Anticonvulsants; Brain Damage, | 1971 |