amitriptyline has been researched along with Adjuvant Arthritis in 4 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Sprague-Dawley rats with adjuvant-induced arthritis were injected daily for 4 weeks with amitriptyline (10 mg/kg) or imipramine (10 mg/kg) or saline, beginning 21 days after the induction of arthritis." | 7.67 | Reduction of arthritis and pain behaviour following chronic administration of amitriptyline or imipramine in rats with adjuvant-induced arthritis. ( Besson, JM; Butler, SH; Godefroy, F; Weil-Fugazza, J, 1985) |
| " Sprague-Dawley rats with adjuvant-induced arthritis were injected daily for 4 weeks with amitriptyline (10 mg/kg) or imipramine (10 mg/kg) or saline, beginning 21 days after the induction of arthritis." | 3.67 | Reduction of arthritis and pain behaviour following chronic administration of amitriptyline or imipramine in rats with adjuvant-induced arthritis. ( Besson, JM; Butler, SH; Godefroy, F; Weil-Fugazza, J, 1985) |
| "Rheumatoid arthritis is a chronic autoimmune disease hallmarked by inflammation in synovial joints." | 1.46 | Regulation of Arthritis Severity by the Acid Sphingomyelinase. ( Becker, JU; Becker, KA; Beckmann, N; Carpinteiro, A; Fassbender, K; Göthert, JR; Gulbins, E; Hessler, G; Kramer, M; Walter, S; Weber, S, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Macsari, I | 1 |
| Besidski, Y | 1 |
| Csjernyik, G | 1 |
| Nilsson, LI | 1 |
| Sandberg, L | 1 |
| Yngve, U | 1 |
| Ahlin, K | 1 |
| Bueters, T | 1 |
| Eriksson, AB | 1 |
| Lund, PE | 1 |
| Venyike, E | 1 |
| Oerther, S | 1 |
| Hygge Blakeman, K | 1 |
| Luo, L | 1 |
| Arvidsson, PI | 1 |
| Beckmann, N | 1 |
| Becker, KA | 1 |
| Walter, S | 1 |
| Becker, JU | 1 |
| Kramer, M | 1 |
| Hessler, G | 1 |
| Weber, S | 1 |
| Göthert, JR | 1 |
| Fassbender, K | 1 |
| Gulbins, E | 1 |
| Carpinteiro, A | 1 |
| Godefroy, F | 2 |
| Butler, SH | 2 |
| Weil-Fugazza, J | 2 |
| Besson, JM | 2 |
4 other studies available for amitriptyline and Adjuvant Arthritis
| Article | Year |
|---|---|
3-Oxoisoindoline-1-carboxamides: potent, state-dependent blockers of voltage-gated sodium channel Na(V)1.7 with efficacy in rat pain models.
Topics: Amides; Analgesics; Animals; Arthritis, Experimental; Carrageenan; CHO Cells; Chronic Pain; Cricetin | 2012 |
Regulation of Arthritis Severity by the Acid Sphingomyelinase.
Topics: Amitriptyline; Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Disease Models, Animal; Gene | 2017 |
Do acute or chronic tricyclic antidepressants modify morphine antinociception in arthritic rats?
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Arthritis; Arthritis, Experimental; Drug S | 1986 |
Reduction of arthritis and pain behaviour following chronic administration of amitriptyline or imipramine in rats with adjuvant-induced arthritis.
Topics: Amitriptyline; Animals; Arthritis; Arthritis, Experimental; Behavior, Animal; Body Weight; Disease M | 1985 |