amitriptyline has been researched along with Adipocere in 18 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Decomposed bone and plasma samples of rats exposed to amitriptyline (AMI) and citalopram (CIT) under different dosing patterns were analyzed." | 1.39 | Discrimination between patterns of drug exposure by toxicological analysis of decomposed skeletal tissues. Part II: Amitriptyline and citalopram. ( Cornthwaite, HM; Watterson, JH, 2013) |
| " Postmortem blood samples from the heart of the orally dosed animals revealed large and variable concentration increases of 99(30-243)% for Ami and 96(52-429)% for the main metabolite 10-OH-Ami at 96 h." | 1.30 | Postmortem amitriptyline pharmacokinetics in pigs after oral and intravenous routes of administration. ( Bjørneboe, A; Hilberg, T; Mørland, J; Ripel, A; Slørdal, L; Smith, AJ, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 12 (66.67) | 18.2507 |
| 2000's | 1 (5.56) | 29.6817 |
| 2010's | 4 (22.22) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Maskell, PD | 1 |
| Watterson, JH | 3 |
| Cornthwaite, HM | 1 |
| Martínez-Ramírez, JA | 1 |
| Strien, J | 1 |
| Walther, G | 1 |
| Peters, FT | 1 |
| Desrosiers, NA | 2 |
| Betit, CC | 1 |
| Dean, D | 2 |
| Wyman, JF | 2 |
| Koski, A | 1 |
| Vuori, E | 1 |
| Ojanperä, I | 1 |
| Sadler, DW | 1 |
| Fuke, C | 3 |
| Court, F | 1 |
| Pounder, DJ | 5 |
| Owen, V | 1 |
| Quigley, C | 1 |
| Hilberg, T | 4 |
| Mørland, J | 4 |
| Bjørneboe, A | 4 |
| McIntyre, IM | 1 |
| King, CV | 1 |
| Skafidis, S | 1 |
| Drummer, OH | 1 |
| Bugge, A | 2 |
| Beylich, KM | 2 |
| Ingum, J | 1 |
| Goff, ML | 1 |
| Brown, WA | 1 |
| Omori, AI | 1 |
| LaPointe, DA | 1 |
| Cox, DE | 1 |
| Smith, D | 1 |
| Kuroda, N | 1 |
| Adams, E | 1 |
| Langford, AM | 2 |
| Ripel, A | 1 |
| Smith, AJ | 1 |
| Slørdal, L | 1 |
| Moriya, F | 1 |
| Hashimoto, Y | 1 |
18 other studies available for amitriptyline and Adipocere
| Article | Year |
|---|---|
Just say no to postmortem drug dose calculations.
Topics: Amitriptyline; Drug Dosage Calculations; Forensic Toxicology; Humans; Pharmacokinetics; Postmortem C | 2021 |
Discrimination between patterns of drug exposure by toxicological analysis of decomposed skeletal tissues. Part II: Amitriptyline and citalopram.
Topics: Amitriptyline; Animals; Bone and Bones; Calibration; Chromatography, High Pressure Liquid; Citalopra | 2013 |
Search for fungi-specific metabolites of four model drugs in postmortem blood as potential indicators of postmortem fungal metabolism.
Topics: Aged; Amitriptyline; Biotransformation; Cardiovascular Agents; Central Nervous System Agents; Chroma | 2016 |
Relative distribution of drugs in decomposed skeletal tissue.
Topics: Administration, Oral; Amitriptyline; Animals; Autopsy; Bone and Bones; Diazepam; Female; Forensic To | 2010 |
Detection of amitriptyline, citalopram, and metabolites in porcine bones following extended outdoor decomposition.
Topics: Amitriptyline; Animals; Antidepressive Agents; Bone and Bones; Chromatography, Liquid; Citalopram; E | 2012 |
Relation of postmortem blood alcohol and drug concentrations in fatal poisonings involving amitriptyline, propoxyphene and promazine.
Topics: Amitriptyline; Dextropropoxyphene; Drug Interactions; Ethanol; Finland; Forensic Medicine; Humans; P | 2005 |
Drug accumulation and elimination in Calliphora vicina larvae.
Topics: Amitriptyline; Animals; Diptera; Humans; Larva; Postmortem Changes; Temazepam; Trazodone; Trimiprami | 1995 |
Postmortem changes in blood amitriptyline concentration.
Topics: Adult; Amitriptyline; Body Fluids; Chromatography, High Pressure Liquid; Drug Overdose; Humans; Male | 1994 |
Postmortem release of amitriptyline from the lungs; a mechanism of postmortem drug redistribution.
Topics: Amitriptyline; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Kidney; Liver; Lung; | 1994 |
Dual ultraviolet wavelength high-performance liquid chromatographic method for the forensic or clinical analysis of seventeen antidepressants and some selected metabolites.
Topics: Amitriptyline; Antidepressive Agents; Chromatography, High Pressure Liquid; Dothiepin; Doxepin; Fore | 1993 |
An animal model of postmortem amitriptyline redistribution.
Topics: Amitriptyline; Animals; Disease Models, Animal; Drug Overdose; Liver; Lung; Male; Nortriptyline; Pos | 1993 |
Preliminary observations of the effects of amitriptyline in decomposing tissues on the development of Parasarcophaga ruficornis (Diptera: Sarcophagidae) and implications of this effect to estimation of postmortem interval.
Topics: Amitriptyline; Animals; Diptera; Forensic Medicine; Larva; Liver; Nortriptyline; Postmortem Changes; | 1993 |
Postmortem diffusion of drugs from gastric residue: an experimental study.
Topics: Acetaminophen; Amitriptyline; Diffusion; Gastrointestinal Contents; Humans; Lithium; Models, Biologi | 1996 |
Site to site variability of postmortem drug concentrations in liver and lung.
Topics: Acetaminophen; Adult; Amitriptyline; Dextropropoxyphene; Female; Humans; Liver; Lung; Male; Middle A | 1996 |
Possible markers for postmortem drug redistribution.
Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Amino Acids; Amitriptyline; Antidepressive Agents | 1997 |
Postmortem amitriptyline pharmacokinetics in pigs after oral and intravenous routes of administration.
Topics: Administration, Oral; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Chromatography, High | 1998 |
Redistribution of basic drugs into cardiac blood from surrounding tissues during early-stages postmortem.
Topics: Adult; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Autopsy; Central Nervous System Sti | 1999 |
Diffusion as a mechanism of postmortem drug redistribution: an experimental study in rats.
Topics: Amitriptyline; Animals; Evaluation Studies as Topic; Forensic Medicine; Kidney; Liver; Lung; Male; M | 1992 |