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amitriptyline and Addiction, Opioid

amitriptyline has been researched along with Addiction, Opioid in 2 studies

Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.

Research Excerpts

ExcerptRelevanceReference
"Benzodiazepine use in the treatment of insomnia may cause benzodiazepine dependence, especially in opiate users."2.69Amitriptyline vs. lorazepam in the treatment of opiate-withdrawal insomnia: a randomized double-blind study. ( Jarusuraisin, N; Srisurapanont, M, 1998)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Tang, J1
Landes, RD1
Srisurapanont, M1
Jarusuraisin, N1

Trials

1 trial available for amitriptyline and Addiction, Opioid

ArticleYear
Amitriptyline vs. lorazepam in the treatment of opiate-withdrawal insomnia: a randomized double-blind study.
    Acta psychiatrica Scandinavica, 1998, Volume: 97, Issue:3

    Topics: Adult; Amitriptyline; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Double-Blind Method; Fe

1998

Other Studies

1 other study available for amitriptyline and Addiction, Opioid

ArticleYear
Some t-tests for N-of-1 trials with serial correlation.
    PloS one, 2020, Volume: 15, Issue:2

    Topics: Amitriptyline; Clinical Trials as Topic; Fibromyalgia; Humans; Monte Carlo Method; Opioid-Related Di

2020