amitriptyline has been researched along with Acute Lung Injury in 1 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Acute Lung Injury: A condition of lung damage that is characterized by bilateral pulmonary infiltrates (PULMONARY EDEMA) rich in NEUTROPHILS, and in the absence of clinical HEART FAILURE. This can represent a spectrum of pulmonary lesions, endothelial and epithelial, due to numerous factors (physical, chemical, or biological).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Infection with avian influenza A H5N1 virus results in acute lung injury (ALI) and has a high mortality rate (52." | 1.56 | Identification of amitriptyline HCl, flavin adenine dinucleotide, azacitidine and calcitriol as repurposing drugs for influenza A H5N1 virus-induced lung injury. ( Huang, F; Jiang, C; Jin, N; Li, C; Li, X; Liu, Q; Qin, Y; Zhang, C; Zhang, Y; Zhao, Y; Zhou, C, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, F | 1 |
| Zhang, C | 1 |
| Liu, Q | 1 |
| Zhao, Y | 1 |
| Zhang, Y | 1 |
| Qin, Y | 1 |
| Li, X | 1 |
| Li, C | 1 |
| Zhou, C | 1 |
| Jin, N | 1 |
| Jiang, C | 1 |
1 other study available for amitriptyline and Acute Lung Injury
| Article | Year |
|---|---|
Identification of amitriptyline HCl, flavin adenine dinucleotide, azacitidine and calcitriol as repurposing drugs for influenza A H5N1 virus-induced lung injury.
Topics: Acute Lung Injury; Amitriptyline; Animals; Azacitidine; Calcitriol; Disease Models, Animal; Drug Rep | 2020 |